These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 34126912)

  • 1. Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents.
    Al-Mahmoudy A; Hassan A; Ibrahim T; Youssif BGM; Taher E; Tantawy M; Abdel-Aal E; Osman N
    Anticancer Agents Med Chem; 2022; 22(5):978-990. PubMed ID: 34126912
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of a promising hit from a new series of pyrazolo[1,5-a]pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment.
    Elgiushy HR; Mohamed SH; Taha H; Sawaf H; Hassan Z; Abou-Taleb NA; El-Labbad EM; Hassan AS; Abouzid KAM; Hammad SF
    Bioorg Chem; 2022 Mar; 120():105646. PubMed ID: 35134645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytotoxic and Apoptotic Effects of Novel Pyrrolo[2,3-d]Pyrimidine Derivatives Containing Urea Moieties on Cancer Cell Lines.
    Kilic-Kurt Z; Bakar-Ates F; Karakas B; Kütük Ö
    Anticancer Agents Med Chem; 2018; 18(9):1303-1312. PubMed ID: 29866023
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
    Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
    Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFR
    Reda N; Mohamed KO; Abdou K; Helwa AA; Elshewy A
    Bioorg Chem; 2024 Apr; 145():107185. PubMed ID: 38350273
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of new pyranoquinolinone heteroannulated to triazolopyrimidine of potential apoptotic antiproliferative activity.
    Ramadan M; Abd El-Aziz M; Elshaier YAMM; Youssif BGM; Brown AB; Fathy HM; Aly AA
    Bioorg Chem; 2020 Dec; 105():104392. PubMed ID: 33137557
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF; Hassaneen HM; Elzayat EM; El-Hallouty SM; El-Manawaty M; Saleh FM; Mohamed Y; El-Zohiry D; Fahmy G; Abdelaal N; Hassanin N; Hossam N
    Anticancer Agents Med Chem; 2019; 19(9):1141-1149. PubMed ID: 30843494
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anticancer activity of newly synthesized 1,1-disubstituted cyclohexane-1-carboxamides: in vitro caspases mediated apoptosis activators in human cancer cell lines and their molecular modeling.
    Abd-Allah WH; Salman A; Sabry Saad S
    Drug Dev Res; 2019 Nov; 80(7):933-947. PubMed ID: 31343754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents.
    Hisham M; Youssif BGM; Osman EEA; Hayallah AM; Abdel-Aziz M
    Eur J Med Chem; 2019 Aug; 176():117-128. PubMed ID: 31108261
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and Anticancer Activity of Novel Chromene Derivatives, Chromeno[2,3-d][1,3]Oxazines, and Chromeno[2,3-d]Pyrimidines.
    Yousif MNM; Fathy U; Yousif NM
    Med Chem; 2023; 19(6):578-585. PubMed ID: 36573048
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
    Sherbiny FF; Bayoumi AH; El-Morsy AM; Sobhy M; Hagras M
    Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, anticancer effect and molecular modeling of new thiazolylpyrazolyl coumarin derivatives targeting VEGFR-2 kinase and inducing cell cycle arrest and apoptosis.
    Mohamed TK; Batran RZ; Elseginy SA; Ali MM; Mahmoud AE
    Bioorg Chem; 2019 Apr; 85():253-273. PubMed ID: 30641320
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.
    Badawi WA; Samir M; Fathy HM; Okda TM; Noureldin MH; Atwa GMK; AboulWafa OM
    Bioorg Chem; 2023 Sep; 138():106610. PubMed ID: 37210828
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents.
    Youssif BGM; Mohamed AM; Osman EEA; Abou-Ghadir OF; Elnaggar DH; Abdelrahman MH; Treamblu L; Gomaa HAM
    Eur J Med Chem; 2019 Sep; 177():1-11. PubMed ID: 31128433
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of some novel quinazolinone derivatives as potent apoptotic inducers.
    Nowar RM; A Osman EE; Abou-Seri SM; El Moghazy SM; Abou El Ella DA
    Future Med Chem; 2018 May; 10(10):1191-1205. PubMed ID: 29749767
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
    Abdelhaleem EF; Abdelhameid MK; Kassab AE; Kandeel MM
    Eur J Med Chem; 2018 Jan; 143():1807-1825. PubMed ID: 29133058
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Eco-friendly Synthesis of Pyrido[2,3-d]pyrimidine Analogs and Their Anticancer and Tyrosine Kinase Inhibition Activities.
    El-Naggar AM; Khalil AK; Zeidan HM; El-Sayed WM
    Anticancer Agents Med Chem; 2017; 17(12):1644-1651. PubMed ID: 28403776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of new 5-(2,6-dichlorophenyl)-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-7-carboxylic acids as p38α MAPK inhibitors: Design, synthesis, antitumor evaluation, molecular docking and in silico studies.
    El-Wakil MH; El-Dershaby HA; Ghazallah RA; El-Yazbi AF; Abd El-Razik HA; Soliman FSG
    Bioorg Chem; 2024 Apr; 145():107226. PubMed ID: 38377818
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel thienopyrimidine-aminothiazole hybrids: Design, synthesis, antimicrobial screening, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and VEGFR-2 inhibition.
    El-Dash Y; Elzayat E; Abdou AM; Hassan RA
    Bioorg Chem; 2021 Sep; 114():105137. PubMed ID: 34237644
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A flavonoid isolated from Streptomyces sp. (ERINLG-4) induces apoptosis in human lung cancer A549 cells through p53 and cytochrome c release caspase dependant pathway.
    Balachandran C; Sangeetha B; Duraipandiyan V; Raj MK; Ignacimuthu S; Al-Dhabi NA; Balakrishna K; Parthasarathy K; Arulmozhi NM; Arasu MV
    Chem Biol Interact; 2014 Dec; 224():24-35. PubMed ID: 25289772
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.