BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 34129856)

  • 21. Computational modelling of dynamic cAMP responses to GPCR agonists for exploration of GLP-1R ligand effects in pancreatic β-cells and neurons.
    Bridge L; Chen S; Jones B
    Cell Signal; 2024 Jul; 119():111153. PubMed ID: 38556030
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist.
    Kawai T; Sun B; Yoshino H; Feng D; Suzuki Y; Fukazawa M; Nagao S; Wainscott DB; Showalter AD; Droz BA; Kobilka TS; Coghlan MP; Willard FS; Kawabe Y; Kobilka BK; Sloop KW
    Proc Natl Acad Sci U S A; 2020 Nov; 117(47):29959-29967. PubMed ID: 33177239
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Association of glucagon-like peptide-1 receptor-targeted imaging probe with in vivo glucagon-like peptide-1 receptor agonist glucose-lowering effects.
    Murakami T; Fujimoto H; Fujita N; Hamamatsu K; Yabe D; Inagaki N
    J Diabetes Investig; 2020 Nov; 11(6):1448-1456. PubMed ID: 32323451
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study.
    Mao D; Cao H; Shi M; Wang CC; Kwong J; Li JJX; Hou Y; Ming X; Lee HM; Tian XY; Wong CK; Chow E; Kong APS; Lui VWY; Chan PKS; Chan JCN
    EBioMedicine; 2021 Mar; 65():103242. PubMed ID: 33684886
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1.
    Hager MV; Clydesdale L; Gellman SH; Sexton PM; Wootten D
    Biochem Pharmacol; 2017 Jul; 136():99-108. PubMed ID: 28363772
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain.
    Runge S; Thøgersen H; Madsen K; Lau J; Rudolph R
    J Biol Chem; 2008 Apr; 283(17):11340-7. PubMed ID: 18287102
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Signalling, trafficking and glucoregulatory properties of glucagon-like peptide-1 receptor agonists exendin-4 and lixisenatide.
    Pickford P; Lucey M; Fang Z; Bitsi S; de la Serna JB; Broichhagen J; Hodson DJ; Minnion J; Rutter GA; Bloom SR; Tomas A; Jones B
    Br J Pharmacol; 2020 Sep; 177(17):3905-3923. PubMed ID: 32436216
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles.
    Bueno AB; Showalter AD; Wainscott DB; Stutsman C; Marín A; Ficorilli J; Cabrera O; Willard FS; Sloop KW
    J Biol Chem; 2016 May; 291(20):10700-15. PubMed ID: 26975372
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Exendin-4 Derivatives with an Albumin-Binding Moiety Show Decreased Renal Retention and Improved GLP-1 Receptor Targeting.
    Kaeppeli SAM; Jodal A; Gotthardt M; Schibli R; Béhé M
    Mol Pharm; 2019 Sep; 16(9):3760-3769. PubMed ID: 31393738
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Receptor-Targeted Photodynamic Therapy of Glucagon-Like Peptide 1 Receptor-Positive Lesions.
    Boss M; Bos D; Frielink C; Sandker G; Bronkhorst P; van Lith SAM; Brom M; Buitinga M; Gotthardt M
    J Nucl Med; 2020 Nov; 61(11):1588-1593. PubMed ID: 32385165
    [TBL] [Abstract][Full Text] [Related]  

  • 31. [
    Zhang P; Zhao Z; Zhang L; Wu W; Xu Y; Pan D; Wang F; Yang M
    Nucl Med Biol; 2019; 74-75():19-24. PubMed ID: 31450071
    [TBL] [Abstract][Full Text] [Related]  

  • 32. GLP-1 receptor agonists stimulate ANGPTL8 production through the PI3K/Akt pathway in a GLP-1 receptor-dependent manner.
    Liu J; Yang K; Xiao W; Le Y; Lang S; Zhang J; Wei R; Yang J; Hong T
    Peptides; 2018 Aug; 106():83-90. PubMed ID: 30003931
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism.
    Lei S; Clydesdale L; Dai A; Cai X; Feng Y; Yang D; Liang YL; Koole C; Zhao P; Coudrat T; Christopoulos A; Wang MW; Wootten D; Sexton PM
    J Biol Chem; 2018 Jun; 293(24):9370-9387. PubMed ID: 29717000
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Blocking of Glucagonlike Peptide-1 Receptors in the Exocrine Pancreas Improves Specificity for β-Cells in a Mouse Model of Type 1 Diabetes.
    Khera E; Zhang L; Roberts S; Nessler I; Sandoval D; Reiner T; Thurber GM
    J Nucl Med; 2019 Nov; 60(11):1635-1641. PubMed ID: 31076502
    [TBL] [Abstract][Full Text] [Related]  

  • 35. [Effects of Exendin-4 on the differentiation of neural stem cells from subventricular zone of adult mice in vitro].
    Zhao F; Xu HY; Ma K; Jiang JP; Zhang J; Dai C; Jin Y; Li P; Sun HT; Wang ZG; Chen XY
    Zhongguo Ying Yong Sheng Li Xue Za Zhi; 2019 May; 35(3):262-267. PubMed ID: 31257810
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents.
    Arakawa M; Ebato C; Mita T; Hirose T; Kawamori R; Fujitani Y; Watada H
    Biochem Biophys Res Commun; 2009 Dec; 390(3):809-14. PubMed ID: 19836346
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium: GLP-1R mediated effects in human myocardium.
    Wallner M; Kolesnik E; Ablasser K; Khafaga M; Wakula P; Ljubojevic S; Thon-Gutschi EM; Sourij H; Kapl M; Edmunds NJ; Kuzmiski JB; Griffith DA; Knez I; Pieske B; von Lewinski D
    J Mol Cell Cardiol; 2015 Dec; 89(Pt B):365-75. PubMed ID: 26432951
    [TBL] [Abstract][Full Text] [Related]  

  • 38. GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation.
    Carlessi R; Chen Y; Rowlands J; Cruzat VF; Keane KN; Egan L; Mamotte C; Stokes R; Gunton JE; Bittencourt PIH; Newsholme P
    Sci Rep; 2017 Jun; 7(1):2661. PubMed ID: 28572610
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The glucagon-like peptide-1 receptor agonist oxyntomodulin enhances beta-cell function but does not inhibit gastric emptying in mice.
    Maida A; Lovshin JA; Baggio LL; Drucker DJ
    Endocrinology; 2008 Nov; 149(11):5670-8. PubMed ID: 18669601
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation.
    Deganutti G; Liang YL; Zhang X; Khoshouei M; Clydesdale L; Belousoff MJ; Venugopal H; Truong TT; Glukhova A; Keller AN; Gregory KJ; Leach K; Christopoulos A; Danev R; Reynolds CA; Zhao P; Sexton PM; Wootten D
    Nat Commun; 2022 Jan; 13(1):92. PubMed ID: 35013280
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.