BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 34135323)

  • 1. Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss.
    Amegandjin CA; Choudhury M; Jadhav V; Carriço JN; Quintal A; Berryer M; Snapyan M; Chattopadhyaya B; Saghatelyan A; Di Cristo G
    Nat Commun; 2021 Jun; 12(1):3653. PubMed ID: 34135323
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
    Haji N; Riebe I; Aguilar-Valles A; Artinian J; Laplante I; Lacaille JC
    Mol Autism; 2020 May; 11(1):29. PubMed ID: 32375878
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tsc1 represses parvalbumin expression and fast-spiking properties in somatostatin lineage cortical interneurons.
    Malik R; Pai EL; Rubin AN; Stafford AM; Angara K; Minasi P; Rubenstein JL; Sohal VS; Vogt D
    Nat Commun; 2019 Nov; 10(1):4994. PubMed ID: 31676823
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells.
    Sakai Y; Kassai H; Nakayama H; Fukaya M; Maeda T; Nakao K; Hashimoto K; Sakagami H; Kano M; Aiba A
    Sci Rep; 2019 Feb; 9(1):2799. PubMed ID: 30808980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation.
    Alsaqati M; Heine VM; Harwood AJ
    Mol Autism; 2020 Oct; 11(1):80. PubMed ID: 33076974
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The specificity and role of microglia in epileptogenesis in mouse models of tuberous sclerosis complex.
    Zhang B; Zou J; Han L; Beeler B; Friedman JL; Griffin E; Piao YS; Rensing NR; Wong M
    Epilepsia; 2018 Sep; 59(9):1796-1806. PubMed ID: 30079598
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tsc1-mTORC1 signaling controls striatal dopamine release and cognitive flexibility.
    Kosillo P; Doig NM; Ahmed KM; Agopyan-Miu AHCW; Wong CD; Conyers L; Threlfell S; Magill PJ; Bateup HS
    Nat Commun; 2019 Nov; 10(1):5426. PubMed ID: 31780742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Characterization of a Subependymal Giant Astrocytoma-Like Cell Line from Murine Astrocyte with mTORC1 Hyperactivation.
    Tang X; Angst G; Haas M; Yang F; Wang C
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33923449
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Corticostriatal Transmission Is Selectively Enhanced in Striatonigral Neurons with Postnatal Loss of Tsc1.
    Benthall KN; Ong SL; Bateup HS
    Cell Rep; 2018 Jun; 23(11):3197-3208. PubMed ID: 29898392
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders.
    Barnes SA; Pinto-Duarte A; Kappe A; Zembrzycki A; Metzler A; Mukamel EA; Lucero J; Wang X; Sejnowski TJ; Markou A; Behrens MM
    Mol Psychiatry; 2015 Oct; 20(10):1161-72. PubMed ID: 26260494
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TSC1 deletion in fibroblasts alleviates lipopolysaccharide-induced acute kidney injury.
    Shen J; Cui ZK; Yao F; Li K; Zhang Y; Chen Z; Zhou Y; Xu S; Zhang Y; Jiang W; Zhang H; Tan K; Liu A; Bai X
    Clin Sci (Lond); 2018 Oct; 132(19):2087-2101. PubMed ID: 30185506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42.
    Xu S; Zhang Y; Wang J; Li K; Tan K; Liang K; Shen J; Cai D; Jin D; Li M; Xiao G; Xu J; Jiang Y; Bai X
    Cell Death Differ; 2018 Sep; 25(9):1549-1566. PubMed ID: 29358671
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.
    Di Nardo A; Lenoël I; Winden KD; Rühmkorf A; Modi ME; Barrett L; Ercan-Herbst E; Venugopal P; Behne R; Lopes CAM; Kleiman RJ; Bettencourt-Dias M; Sahin M
    Cell Rep; 2020 Jun; 31(12):107780. PubMed ID: 32579942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling.
    Martin P; Wagh V; Reis SA; Erdin S; Beauchamp RL; Shaikh G; Talkowski M; Thiele E; Sheridan SD; Haggarty SJ; Ramesh V
    Mol Autism; 2020; 11(1):2. PubMed ID: 31921404
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p75 Neurotrophin Receptor Activation Regulates the Timing of the Maturation of Cortical Parvalbumin Interneuron Connectivity and Promotes Juvenile-like Plasticity in Adult Visual Cortex.
    Baho E; Chattopadhyaya B; Lavertu-Jolin M; Mazziotti R; Awad PN; Chehrazi P; Groleau M; Jahannault-Talignani C; Vaucher E; Ango F; Pizzorusso T; Baroncelli L; Di Cristo G
    J Neurosci; 2019 Jun; 39(23):4489-4510. PubMed ID: 30936240
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arid1b haploinsufficiency in parvalbumin- or somatostatin-expressing interneurons leads to distinct ASD-like and ID-like behavior.
    Smith AL; Jung EM; Jeon BT; Kim WY
    Sci Rep; 2020 May; 10(1):7834. PubMed ID: 32398858
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice.
    Khan A; de Jong LA; Kamenski ME; Higa KK; Lucero JD; Young JW; Behrens MM; Powell SB
    Neuroscience; 2017 Mar; 345():166-175. PubMed ID: 27890827
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural alterations in fast-spiking GABAergic interneurons in a model of posttraumatic neocortical epileptogenesis.
    Gu F; Parada I; Shen F; Li J; Bacci A; Graber K; Taghavi RM; Scalise K; Schwartzkroin P; Wenzel J; Prince DA
    Neurobiol Dis; 2017 Dec; 108():100-114. PubMed ID: 28823934
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of noise-induced hearing loss on parvalbumin and perineuronal net expression in the mouse primary auditory cortex.
    Nguyen A; Khaleel HM; Razak KA
    Hear Res; 2017 Jul; 350():82-90. PubMed ID: 28460252
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Osteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice.
    Liu W; Wang Z; Yang J; Wang Y; Li K; Huang B; Yan B; Wang T; Li M; Zou Z; Yang J; Xiao G; Cui ZK; Liu A; Bai X
    Open Biol; 2019 May; 9(5):180262. PubMed ID: 31088250
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.