BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 34142658)

  • 1. Dependency of human and murine LKB1-inactivated lung cancer on aberrant CRTC-CREB activation.
    Zhou X; Li JW; Chen Z; Ni W; Li X; Yang R; Shen H; Liu J; DeMayo FJ; Lu J; Kaye FJ; Wu L
    Elife; 2021 Jun; 10():. PubMed ID: 34142658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth.
    Chen Z; Li JL; Lin S; Cao C; Gimbrone NT; Yang R; Fu DA; Carper MB; Haura EB; Schabath MB; Lu J; Amelio AL; Cress WD; Kaye FJ; Wu L
    J Clin Invest; 2016 Jun; 126(6):2267-79. PubMed ID: 27140397
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced activity of the CREB co-activator Crtc1 in LKB1 null lung cancer.
    Komiya T; Coxon A; Park Y; Chen WD; Zajac-Kaye M; Meltzer P; Karpova T; Kaye FJ
    Oncogene; 2010 Mar; 29(11):1672-80. PubMed ID: 20010869
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of INSL4 Signaling in Sustaining the Growth and Viability of LKB1-Inactivated Lung Cancer.
    Yang R; Li SW; Chen Z; Zhou X; Ni W; Fu DA; Lu J; Kaye FJ; Wu L
    J Natl Cancer Inst; 2019 Jul; 111(7):664-674. PubMed ID: 30423141
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non-small cell lung cancer.
    Rodón L; Svensson RU; Wiater E; Chun MGH; Tsai WW; Eichner LJ; Shaw RJ; Montminy M
    Sci Adv; 2019 Jul; 5(7):eaaw6455. PubMed ID: 31355336
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion.
    Gu Y; Lin S; Li JL; Nakagawa H; Chen Z; Jin B; Tian L; Ucar DA; Shen H; Lu J; Hochwald SN; Kaye FJ; Wu L
    Oncogene; 2012 Jan; 31(4):469-79. PubMed ID: 21706049
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP--implications for CREB-dependent gene transcription.
    Heinrich A; von der Heyde AS; Böer U; Phu do T; Tzvetkov M; Oetjen E
    Cell Signal; 2013 Jan; 25(1):113-25. PubMed ID: 23000340
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB.
    Mair W; Morantte I; Rodrigues AP; Manning G; Montminy M; Shaw RJ; Dillin A
    Nature; 2011 Feb; 470(7334):404-8. PubMed ID: 21331044
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer.
    Cao C; Gao R; Zhang M; Amelio AL; Fallahi M; Chen Z; Gu Y; Hu C; Welsh EA; Engel BE; Haura EB; Cress WD; Wu L; Zajac-Kaye M; Kaye FJ
    J Natl Cancer Inst; 2015 Jan; 107(1):358. PubMed ID: 25465874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade.
    Katoh Y; Takemori H; Lin XZ; Tamura M; Muraoka M; Satoh T; Tsuchiya Y; Min L; Doi J; Miyauchi A; Witters LA; Nakamura H; Okamoto M
    FEBS J; 2006 Jun; 273(12):2730-48. PubMed ID: 16817901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The AMPK-Related Kinases SIK1 and SIK3 Mediate Key Tumor-Suppressive Effects of LKB1 in NSCLC.
    Hollstein PE; Eichner LJ; Brun SN; Kamireddy A; Svensson RU; Vera LI; Ross DS; Rymoff TJ; Hutchins A; Galvez HM; Williams AE; Shokhirev MN; Screaton RA; Berdeaux R; Shaw RJ
    Cancer Discov; 2019 Nov; 9(11):1606-1627. PubMed ID: 31350328
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LKB1 Loss induces characteristic patterns of gene expression in human tumors associated with NRF2 activation and attenuation of PI3K-AKT.
    Kaufman JM; Amann JM; Park K; Arasada RR; Li H; Shyr Y; Carbone DP
    J Thorac Oncol; 2014 Jun; 9(6):794-804. PubMed ID: 24828662
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The CRTC1-NEDD9 signaling axis mediates lung cancer progression caused by LKB1 loss.
    Feng Y; Wang Y; Wang Z; Fang Z; Li F; Gao Y; Liu H; Xiao T; Li F; Zhou Y; Zhai Q; Liu X; Sun Y; Bardeesy N; Wong KK; Chen H; Xiong ZQ; Ji H
    Cancer Res; 2012 Dec; 72(24):6502-11. PubMed ID: 23074285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation and expression of endogenous CREB-regulated transcription coactivators (CRTC) 1, 2 and 3 in the rat adrenal gland.
    Smith LIF; Zhao Z; Walker J; Lightman S; Spiga F
    J Neuroendocrinol; 2021 Jan; 33(1):e12920. PubMed ID: 33314405
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hippocampal Salt-Inducible Kinase 2 Plays a Role in Depression via the CREB-Regulated Transcription Coactivator 1-cAMP Response Element Binding-Brain-Derived Neurotrophic Factor Pathway.
    Jiang B; Wang H; Wang JL; Wang YJ; Zhu Q; Wang CN; Song L; Gao TT; Wang Y; Meng GL; Wu F; Ling Y; Zhang W; Li JX
    Biol Psychiatry; 2019 Apr; 85(8):650-666. PubMed ID: 30503507
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increasing CRTC1 function in the dentate gyrus during memory formation or reactivation increases memory strength without compromising memory quality.
    Sekeres MJ; Mercaldo V; Richards B; Sargin D; Mahadevan V; Woodin MA; Frankland PW; Josselyn SA
    J Neurosci; 2012 Dec; 32(49):17857-68. PubMed ID: 23223304
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling.
    Wang T; Wiater E; Zhang X; Thomas JB; Montminy M
    Proc Natl Acad Sci U S A; 2021 Mar; 118(12):. PubMed ID: 33723074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscle.
    Branvold DJ; Allred DR; Beckstead DJ; Kim HJ; Fillmore N; Condon BM; Brown JD; Sudweeks SN; Thomson DM; Winder WW
    J Appl Physiol (1985); 2008 Oct; 105(4):1218-27. PubMed ID: 18669938
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural Insights into the CRTC2-CREB Complex Assembly on CRE.
    Song Y; Zhai L; Valencia Swain J; Chen Y; Wang P; Chen L; Liu Y; Xiang S
    J Mol Biol; 2018 Jun; 430(13):1926-1939. PubMed ID: 29733854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual Role of CREB in The Regulation of VSMC Proliferation: Mode of Activation Determines Pro- or Anti-Mitogenic Function.
    Hudson C; Kimura TE; Duggirala A; Sala-Newby GB; Newby AC; Bond M
    Sci Rep; 2018 Mar; 8(1):4904. PubMed ID: 29559698
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.