220 related articles for article (PubMed ID: 34144037)
1. PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA.
Yano K; Takahashi RU; Shiotani B; Abe J; Shidooka T; Sudo Y; Yamamoto Y; Kan S; Sakagami H; Tahara H
J Biol Chem; 2021 Jul; 297(1):100882. PubMed ID: 34144037
[TBL] [Abstract][Full Text] [Related]
2. TSSC4 is a component of U5 snRNP that promotes tri-snRNP formation.
Klimešová K; Vojáčková J; Radivojević N; Vandermoere F; Bertrand E; Verheggen C; Staněk D
Nat Commun; 2021 Jun; 12(1):3646. PubMed ID: 34131137
[TBL] [Abstract][Full Text] [Related]
3. PRPF19 promotes tongue cancer growth and chemoradiotherapy resistance.
He Y; Huang C; Cai K; Liu P; Chen X; Xu YI; Ming Z; Liu Q; Xie Q; Xia X; Sun Y; Luo J; Wei R
Acta Biochim Biophys Sin (Shanghai); 2021 Jul; 53(7):893-902. PubMed ID: 33954334
[TBL] [Abstract][Full Text] [Related]
4. Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence.
Tang Y; Horikawa I; Ajiro M; Robles AI; Fujita K; Mondal AM; Stauffer JK; Zheng ZM; Harris CC
Oncogene; 2013 May; 32(22):2792-8. PubMed ID: 22777358
[TBL] [Abstract][Full Text] [Related]
5. A genome-wide siRNA screen for regulators of tumor suppressor p53 activity in human non-small cell lung cancer cells identifies components of the RNA splicing machinery as targets for anticancer treatment.
Siebring-van Olst E; Blijlevens M; de Menezes RX; van der Meulen-Muileman IH; Smit EF; van Beusechem VW
Mol Oncol; 2017 May; 11(5):534-551. PubMed ID: 28296343
[TBL] [Abstract][Full Text] [Related]
6. Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4.
Chandler DS; Singh RK; Caldwell LC; Bitler JL; Lozano G
Cancer Res; 2006 Oct; 66(19):9502-8. PubMed ID: 17018606
[TBL] [Abstract][Full Text] [Related]
7. Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing.
Gerhart SV; Kellner WA; Thompson C; Pappalardi MB; Zhang XP; Montes de Oca R; Penebre E; Duncan K; Boriack-Sjodin A; Le B; Majer C; McCabe MT; Carpenter C; Johnson N; Kruger RG; Barbash O
Sci Rep; 2018 Jun; 8(1):9711. PubMed ID: 29946150
[TBL] [Abstract][Full Text] [Related]
8. Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy.
Van Alstyne M; Simon CM; Sardi SP; Shihabuddin LS; Mentis GZ; Pellizzoni L
Genes Dev; 2018 Aug; 32(15-16):1045-1059. PubMed ID: 30012555
[TBL] [Abstract][Full Text] [Related]
9. Mdm2 Splice isoforms regulate the p53/Mdm2/Mdm4 regulatory circuit via RING domain-mediated ubiquitination of p53 and Mdm4.
Fan C; Wang X
Cell Cycle; 2017 Apr; 16(7):660-664. PubMed ID: 28166445
[TBL] [Abstract][Full Text] [Related]
10. Identification of a DNA Damage-Induced Alternative Splicing Pathway That Regulates p53 and Cellular Senescence Markers.
Chen J; Crutchley J; Zhang D; Owzar K; Kastan MB
Cancer Discov; 2017 Jul; 7(7):766-781. PubMed ID: 28288992
[TBL] [Abstract][Full Text] [Related]
11. The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway.
Zhao Y; Wu M; Li J; Meng P; Chen J; Huang Z; Xu J; Wen Z; Zhang W; Zhang Y
Cell Death Dis; 2021 Oct; 12(10):906. PubMed ID: 34611130
[TBL] [Abstract][Full Text] [Related]
12. Comprehensive analysis of PRPF19 immune infiltrates, DNA methylation, senescence-associated secretory phenotype and ceRNA network in bladder cancer.
Wang Y; Wang J; He J; Ji B; Pang Z; Wang J; Liu Y; Ren M
Front Immunol; 2023; 14():1289198. PubMed ID: 38022515
[TBL] [Abstract][Full Text] [Related]
13. HdmX overexpression inhibits oncogene induced cellular senescence.
Miller KR; Kelley K; Tuttle R; Berberich SJ
Cell Cycle; 2010 Aug; 9(16):3376-82. PubMed ID: 20724842
[TBL] [Abstract][Full Text] [Related]
14. MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma.
Hüllein J; Słabicki M; Rosolowski M; Jethwa A; Habringer S; Tomska K; Kurilov R; Lu J; Scheinost S; Wagener R; Huang Z; Lukas M; Yavorska O; Helfrich H; Scholtysik R; Bonneau K; Tedesco D; Küppers R; Klapper W; Pott C; Stilgenbauer S; Burkhardt B; Löffler M; Trümper LH; Hummel M; Brors B; Zapatka M; Siebert R; Kreuz M; Keller U; Huber W; Zenz T
Cancer Res; 2019 Jun; 79(12):3125-3138. PubMed ID: 31000522
[TBL] [Abstract][Full Text] [Related]
15. MDM4 expression in fibrolamellar hepatocellular carcinoma.
Karki A; Putra J; Kim SS; Laquaglia MJ; Perez-Atayde AR; Sadri-Vakili G; Vakili K
Oncol Rep; 2019 Oct; 42(4):1487-1496. PubMed ID: 31322272
[TBL] [Abstract][Full Text] [Related]
16. Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery.
Bezzi M; Teo SX; Muller J; Mok WC; Sahu SK; Vardy LA; Bonday ZQ; Guccione E
Genes Dev; 2013 Sep; 27(17):1903-16. PubMed ID: 24013503
[TBL] [Abstract][Full Text] [Related]
17. Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity.
Bardot B; Bouarich-Bourimi R; Leemput J; Lejour V; Hamon A; Plancke L; Jochemsen AG; Simeonova I; Fang M; Toledo F
Oncogene; 2015 May; 34(22):2943-8. PubMed ID: 25088193
[TBL] [Abstract][Full Text] [Related]
18. Identification and expression of a novel MDM4 splice variant in human glioma.
Wang X; Sheng P; Guo X; Wang J; Hou L; Hu G; Luo C; Dong Y; Lu Y
Brain Res; 2013 Nov; 1537():260-6. PubMed ID: 23994448
[TBL] [Abstract][Full Text] [Related]
19. Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
AbuHammad S; Cullinane C; Martin C; Bacolas Z; Ward T; Chen H; Slater A; Ardley K; Kirby L; Chan KT; Brajanovski N; Smith LK; Rao AD; Lelliott EJ; Kleinschmidt M; Vergara IA; Papenfuss AT; Lau P; Ghosh P; Haupt S; Haupt Y; Sanij E; Poortinga G; Pearson RB; Falk H; Curtis DJ; Stupple P; Devlin M; Street I; Davies MA; McArthur GA; Sheppard KE
Proc Natl Acad Sci U S A; 2019 Sep; 116(36):17990-18000. PubMed ID: 31439820
[TBL] [Abstract][Full Text] [Related]
20. The long and the short of it: the MDM4 tail so far.
Haupt S; Mejía-Hernández JO; Vijayakumaran R; Keam SP; Haupt Y
J Mol Cell Biol; 2019 Mar; 11(3):231-244. PubMed ID: 30689920
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]