BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 34145035)

  • 1. CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.
    Laine A; Nagelli SG; Farrington C; Butt U; Cvrljevic AN; Vainonen JP; Feringa FM; Grönroos TJ; Gautam P; Khan S; Sihto H; Qiao X; Pavic K; Connolly DC; Kronqvist P; Elo LL; Maurer J; Wennerberg K; Medema RH; Joensuu H; Peuhu E; de Visser K; Narla G; Westermarck J
    Cancer Res; 2021 Aug; 81(16):4319-4331. PubMed ID: 34145035
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CIP2A coordinates phosphosignaling, mitosis, and the DNA damage response.
    Nagelli S; Westermarck J
    Trends Cancer; 2024 Jan; 10(1):52-64. PubMed ID: 37793965
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis.
    De Marco Zompit M; Esteban MT; Mooser C; Adam S; Rossi SE; Jeanrenaud A; Leimbacher PA; Fink D; Shorrocks AK; Blackford AN; Durocher D; Stucki M
    Nat Commun; 2022 Jul; 13(1):4143. PubMed ID: 35842428
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.
    Laine A; Sihto H; Come C; Rosenfeldt MT; Zwolinska A; Niemelä M; Khanna A; Chan EK; Kähäri VM; Kellokumpu-Lehtinen PL; Sansom OJ; Evan GI; Junttila MR; Ryan KM; Marine JC; Joensuu H; Westermarck J
    Cancer Discov; 2013 Feb; 3(2):182-97. PubMed ID: 23306062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Micropeptide CIP2A-BP encoded by LINC00665 inhibits triple-negative breast cancer progression.
    Guo B; Wu S; Zhu X; Zhang L; Deng J; Li F; Wang Y; Zhang S; Wu R; Lu J; Zhou Y
    EMBO J; 2020 Jan; 39(1):e102190. PubMed ID: 31755573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CIP2A is a target of bortezomib in human triple negative breast cancer cells.
    Tseng LM; Liu CY; Chang KC; Chu PY; Shiau CW; Chen KF
    Breast Cancer Res; 2012 Apr; 14(2):R68. PubMed ID: 22537901
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression.
    Liu CY; Huang TT; Chen YT; Chen JL; Chu PY; Huang CT; Wang WL; Lau KY; Dai MS; Shiau CW; Tseng LM
    EBioMedicine; 2019 Feb; 40():263-275. PubMed ID: 30651219
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CIP2A signature reveals the MYC dependency of CIP2A-regulated phenotypes and its clinical association with breast cancer subtypes.
    Niemelä M; Kauko O; Sihto H; Mpindi JP; Nicorici D; Pernilä P; Kallioniemi OP; Joensuu H; Hautaniemi S; Westermarck J
    Oncogene; 2012 Sep; 31(39):4266-78. PubMed ID: 22249265
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cip2a promotes cell cycle progression in triple-negative breast cancer cells by regulating the expression and nuclear export of p27Kip1.
    Liu H; Qiu H; Song Y; Liu Y; Wang H; Lu M; Deng M; Gu Y; Yin J; Luo K; Zhang Z; Jia X; Zheng G; He Z
    Oncogene; 2017 Apr; 36(14):1952-1964. PubMed ID: 27694903
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disrupting PHF8-TOPBP1 connection elicits a breast tumor-specific vulnerability to chemotherapeutics.
    Ma S; Zhang J; Guo Q; Cao C; Bao K; Liu L; Chen CD; Liu Z; Yang J; Yang N; Yao Z; Shi L
    Cancer Lett; 2022 Apr; 530():29-44. PubMed ID: 35051531
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells.
    Liu CY; Hung MH; Wang DS; Chu PY; Su JC; Teng TH; Huang CT; Chao TT; Wang CY; Shiau CW; Tseng LM; Chen KF
    Breast Cancer Res; 2014 Sep; 16(5):431. PubMed ID: 25228280
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity.
    Jeong AL; Lee S; Park JS; Han S; Jang CY; Lim JS; Lee MS; Yang Y
    J Biol Chem; 2014 Jan; 289(1):28-40. PubMed ID: 24214971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer.
    Adam S; Rossi SE; Moatti N; De Marco Zompit M; Xue Y; Ng TF; Álvarez-Quilón A; Desjardins J; Bhaskaran V; Martino G; Setiaputra D; Noordermeer SM; Ohsumi TK; Hustedt N; Szilard RK; Chaudhary N; Munro M; Veloso A; Melo H; Yin SY; Papp R; Young JTF; Zinda M; Stucki M; Durocher D
    Nat Cancer; 2021 Dec; 2(12):1357-1371. PubMed ID: 35121901
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genistein targets the cancerous inhibitor of PP2A to induce growth inhibition and apoptosis in breast cancer cells.
    Zhao Q; Zhao M; Parris AB; Xing Y; Yang X
    Int J Oncol; 2016 Sep; 49(3):1203-10. PubMed ID: 27574003
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constitutive CHK1 Expression Drives a pSTAT3-CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth.
    Khanna A; Thoms JAI; Stringer BW; Chung SA; Ensbey KS; Jue TR; Jahan Z; Subramanian S; Anande G; Shen H; Unnikrishnan A; McDonald KL; Day BW; Pimanda JE
    Mol Cancer Res; 2020 May; 18(5):709-722. PubMed ID: 32079743
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FL118 inhibits viability and induces apoptosis of colorectal cancer cells via inactivating the CIP2A/PP2A axis.
    Lin X; Gao M; Zhang A; Tong J; Zhang X; Su Q; Yang Z; Gao H; Jiang G
    Life Sci; 2019 Dec; 239():117074. PubMed ID: 31751585
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2,5-Dimethyl Celecoxib Inhibits Proliferation and Cell Cycle and Induces Apoptosis in Glioblastoma by Suppressing CIP2A/PP2A/Akt Signaling Axis.
    Gao D; Nyalali AMK; Hou Y; Xu Y; Zhou J; Zhao W; Huang B; Li F
    J Mol Neurosci; 2021 Aug; 71(8):1703-1713. PubMed ID: 33400072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer.
    Baker LA; Holliday H; Roden D; Krisp C; Wu SZ; Junankar S; Serandour AA; Mohammed H; Nair R; Sankaranarayanan G; Law AMK; McFarland A; Simpson PT; Lakhani S; Dodson E; Selinger C; Anderson L; Samimi G; Hacker NF; Lim E; Ormandy CJ; Naylor MJ; Simpson K; Nikolic I; O'Toole S; Kaplan W; Cowley MJ; Carroll JS; Molloy M; Swarbrick A
    Breast Cancer Res; 2020 Jun; 22(1):63. PubMed ID: 32527287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Arctigenin inhibits triple-negative breast cancers by targeting CIP2A to reactivate protein phosphatase 2A.
    Huang Q; Qin S; Yuan X; Zhang L; Ji J; Liu X; Ma W; Zhang Y; Liu P; Sun Z; Zhang J; Liu Y
    Oncol Rep; 2017 Jul; 38(1):598-606. PubMed ID: 28560452
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upregulation of CIP2A in estrogen depletion-resistant breast cancer cells treated with low-dose everolimus.
    Nishio E; Hayashi T; Akaza M; Hisatomi Y; Hikichi M; Fujii T; Utsumi T; Harada N; Shimono Y
    FEBS Open Bio; 2020 Oct; 10(10):2072-2080. PubMed ID: 32810922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.