BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 34145365)

  • 21. Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.
    Rogawski DS; Deng J; Li H; Miao H; Borkin D; Purohit T; Song J; Chase J; Li S; Ndoj J; Klossowski S; Kim E; Mao F; Zhou B; Ropa J; Krotoska MZ; Jin Z; Ernst P; Feng X; Huang G; Nishioka K; Kelly S; He M; Wen B; Sun D; Muntean A; Dou Y; Maillard I; Cierpicki T; Grembecka J
    Nat Commun; 2021 May; 12(1):2792. PubMed ID: 33990599
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants.
    Siu MT; Butcher DT; Turinsky AL; Cytrynbaum C; Stavropoulos DJ; Walker S; Caluseriu O; Carter M; Lou Y; Nicolson R; Georgiades S; Szatmari P; Anagnostou E; Scherer SW; Choufani S; Brudno M; Weksberg R
    Clin Epigenetics; 2019 Jul; 11(1):103. PubMed ID: 31311581
    [TBL] [Abstract][Full Text] [Related]  

  • 23. De novo loss-of-function variants of ASH1L are associated with an emergent neurodevelopmental disorder.
    Shen W; Krautscheid P; Rutz AM; Bayrak-Toydemir P; Dugan SL
    Eur J Med Genet; 2019 Jan; 62(1):55-60. PubMed ID: 29753921
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Impaired KDM2B-mediated PRC1 recruitment to chromatin causes defective neural stem cell self-renewal and ASD/ID-like behaviors.
    Gao Y; Duque-Wilckens N; Aljazi MB; Moeser AJ; Mias GI; Robison AJ; Zhang Y; He J
    iScience; 2022 Feb; 25(2):103742. PubMed ID: 35128353
    [TBL] [Abstract][Full Text] [Related]  

  • 25. ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.
    Zhu L; Li Q; Wong SH; Huang M; Klein BJ; Shen J; Ikenouye L; Onishi M; Schneidawind D; Buechele C; Hansen L; Duque-Afonso J; Zhu F; Martin GM; Gozani O; Majeti R; Kutateladze TG; Cleary ML
    Cancer Discov; 2016 Jul; 6(7):770-83. PubMed ID: 27154821
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder.
    Kogan JH; Gross AK; Featherstone RE; Shin R; Chen Q; Heusner CL; Adachi M; Lin A; Walton NM; Miyoshi S; Miyake S; Tajinda K; Ito H; Siegel SJ; Matsumoto M
    J Neurosci; 2015 Dec; 35(49):16282-94. PubMed ID: 26658876
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Analysis of a Set of KDM5C Regulatory Genes Mutated in Neurodevelopmental Disorders Identifies Temporal Coexpression Brain Signatures.
    Poeta L; Padula A; Lioi MB; van Bokhoven H; Miano MG
    Genes (Basel); 2021 Jul; 12(7):. PubMed ID: 34356104
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Epigenetics of Autism Spectrum Disorder: Histone Deacetylases.
    Tseng CJ; McDougle CJ; Hooker JM; Zürcher NR
    Biol Psychiatry; 2022 Jun; 91(11):922-933. PubMed ID: 35120709
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A perspective on molecular signalling dysfunction, its clinical relevance and therapeutics in autism spectrum disorder.
    Purushotham SS; Reddy NMN; D'Souza MN; Choudhury NR; Ganguly A; Gopalakrishna N; Muddashetty R; Clement JP
    Exp Brain Res; 2022 Oct; 240(10):2525-2567. PubMed ID: 36063192
    [TBL] [Abstract][Full Text] [Related]  

  • 30. ASH1L contributes to oocyte apoptosis by regulating DNA damage.
    Zhang T; Ren T; Lin H; Tong Y; Zhang J; Nie J; Zhu Y; Wang Y; Jin B; Zhang C; Chen T; He M
    Am J Physiol Cell Physiol; 2022 Oct; 323(4):C1264-C1273. PubMed ID: 36094439
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.
    Orefice LL; Mosko JR; Morency DT; Wells MF; Tasnim A; Mozeika SM; Ye M; Chirila AM; Emanuel AJ; Rankin G; Fame RM; Lehtinen MK; Feng G; Ginty DD
    Cell; 2019 Aug; 178(4):867-886.e24. PubMed ID: 31398341
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Neurobiology of ARID1B haploinsufficiency related to neurodevelopmental and psychiatric disorders.
    Moffat JJ; Smith AL; Jung EM; Ka M; Kim WY
    Mol Psychiatry; 2022 Jan; 27(1):476-489. PubMed ID: 33686214
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in Mice.
    Brinkmeier ML; Geister KA; Jones M; Waqas M; Maillard I; Camper SA
    Biol Reprod; 2015 Nov; 93(5):121. PubMed ID: 26333994
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity.
    Xia M; Liu J; Liu S; Chen K; Lin H; Jiang M; Xu X; Xue Y; Liu W; Gu Y; Zhang X; Li Z; Yi L; Qian Y; Zhou C; Li R; Zhang X; Li Z; Cao X
    Nat Commun; 2017 Jun; 8():15818. PubMed ID: 28598443
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.
    Casingal CR; Kikkawa T; Inada H; Sasaki Y; Osumi N
    Mol Brain; 2020 Dec; 13(1):167. PubMed ID: 33323119
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.
    D'Gama AM; Pochareddy S; Li M; Jamuar SS; Reiff RE; Lam AN; Sestan N; Walsh CA
    Neuron; 2015 Dec; 88(5):910-917. PubMed ID: 26637798
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Lateral habenula dysfunctions in Tm4sf2
    Murru L; Ponzoni L; Longatti A; Mazzoleni S; Giansante G; Bassani S; Sala M; Passafaro M
    Neurobiol Dis; 2021 Jan; 148():105189. PubMed ID: 33227491
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome.
    Balemans MC; Kasri NN; Kopanitsa MV; Afinowi NO; Ramakers G; Peters TA; Beynon AJ; Janssen SM; van Summeren RC; Eeftens JM; Eikelenboom N; Benevento M; Tachibana M; Shinkai Y; Kleefstra T; van Bokhoven H; Van der Zee CE
    Hum Mol Genet; 2013 Mar; 22(5):852-66. PubMed ID: 23175442
    [TBL] [Abstract][Full Text] [Related]  

  • 39. CHD8 haploinsufficiency results in autistic-like phenotypes in mice.
    Katayama Y; Nishiyama M; Shoji H; Ohkawa Y; Kawamura A; Sato T; Suyama M; Takumi T; Miyakawa T; Nakayama KI
    Nature; 2016 Sep; 537(7622):675-679. PubMed ID: 27602517
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Phenotypic spectrum associated with PTCHD1 deletions and truncating mutations includes intellectual disability and autism spectrum disorder.
    Chaudhry A; Noor A; Degagne B; Baker K; Bok LA; Brady AF; Chitayat D; Chung BH; Cytrynbaum C; Dyment D; Filges I; Helm B; Hutchison HT; Jeng LJ; Laumonnier F; Marshall CR; Menzel M; Parkash S; Parker MJ; ; Raymond LF; Rideout AL; Roberts W; Rupps R; Schanze I; Schrander-Stumpel CT; Speevak MD; Stavropoulos DJ; Stevens SJ; Thomas ER; Toutain A; Vergano S; Weksberg R; Scherer SW; Vincent JB; Carter MT
    Clin Genet; 2015 Sep; 88(3):224-33. PubMed ID: 25131214
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.