147 related articles for article (PubMed ID: 34146191)
1. Two-pore physiologically based pharmacokinetic model validation using whole-body biodistribution of trastuzumab and different-size fragments in mice.
Li Z; Li Y; Chang HP; Yu X; Shah DK
J Pharmacokinet Pharmacodyn; 2021 Oct; 48(5):743-762. PubMed ID: 34146191
[TBL] [Abstract][Full Text] [Related]
2. Two-pore physiologically based pharmacokinetic model with de novo derived parameters for predicting plasma PK of different size protein therapeutics.
Li Z; Shah DK
J Pharmacokinet Pharmacodyn; 2019 Jun; 46(3):305-318. PubMed ID: 31028591
[TBL] [Abstract][Full Text] [Related]
3. A Two-Pore Physiologically Based Pharmacokinetic Model to Predict Subcutaneously Administered Different-Size Antibody/Antibody Fragments.
Li Z; Yu X; Li Y; Verma A; Chang HP; Shah DK
AAPS J; 2021 May; 23(3):62. PubMed ID: 33942169
[TBL] [Abstract][Full Text] [Related]
4. Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human.
Shah DK; Betts AM
J Pharmacokinet Pharmacodyn; 2012 Feb; 39(1):67-86. PubMed ID: 22143261
[TBL] [Abstract][Full Text] [Related]
5. Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1.
Khot A; Tibbitts J; Rock D; Shah DK
AAPS J; 2017 Nov; 19(6):1715-1734. PubMed ID: 28808917
[TBL] [Abstract][Full Text] [Related]
6. Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches.
Eigenmann MJ; Karlsen TV; Krippendorff BF; Tenstad O; Fronton L; Otteneder MB; Wiig H
J Physiol; 2017 Dec; 595(24):7311-7330. PubMed ID: 28960303
[TBL] [Abstract][Full Text] [Related]
7. Clinical validation of translational antibody PBPK model using tissue distribution data generated with
Liu S; Li Z; Huisman M; Shah DK
J Pharmacokinet Pharmacodyn; 2023 Oct; 50(5):377-394. PubMed ID: 37382712
[TBL] [Abstract][Full Text] [Related]
8. Development of a Physiologically-Based Pharmacokinetic Model for Whole-Body Disposition of MMAE Containing Antibody-Drug Conjugate in Mice.
Chang HP; Li Z; Shah DK
Pharm Res; 2022 Jan; 39(1):1-24. PubMed ID: 35044590
[TBL] [Abstract][Full Text] [Related]
9. PBPK model for antibody disposition in mouse brain: validation using large-pore microdialysis data.
Wu S; Le Prieult F; Phipps CJ; Mezler M; Shah DK
J Pharmacokinet Pharmacodyn; 2022 Dec; 49(6):579-592. PubMed ID: 36088452
[TBL] [Abstract][Full Text] [Related]
10. Effect of Size on Solid Tumor Disposition of Protein Therapeutics.
Li Z; Li Y; Chang HP; Chang HY; Guo L; Shah DK
Drug Metab Dispos; 2019 Oct; 47(10):1136-1145. PubMed ID: 31387870
[TBL] [Abstract][Full Text] [Related]
11. Whole-Body Disposition and Physiologically Based Pharmacokinetic Modeling of Adeno-Associated Viruses and the Transgene Product.
Liu S; Chowdhury EA; Xu V; Jerez A; Mahmood L; Ly BQ; Le HK; Nguyen A; Rajwade A; Meno-Tetang G; Shah DK
J Pharm Sci; 2024 Jan; 113(1):141-157. PubMed ID: 37805073
[TBL] [Abstract][Full Text] [Related]
12. Translational two-pore PBPK model to characterize whole-body disposition of different-size endogenous and exogenous proteins.
Liu S; Li Y; Li Z; Wu S; Harrold JM; Shah DK
J Pharmacokinet Pharmacodyn; 2024 May; ():. PubMed ID: 38691205
[TBL] [Abstract][Full Text] [Related]
13. Whole-Body Physiologically Based Pharmacokinetic Modeling of Trastuzumab and Prediction of Human Pharmacokinetics.
Bae DJ; Kim SY; Bae SM; Hwang AK; Pak KC; Yoon S; Lim HS
J Pharm Sci; 2019 Jun; 108(6):2180-2190. PubMed ID: 30716331
[TBL] [Abstract][Full Text] [Related]
14. A translational platform PBPK model for antibody disposition in the brain.
Chang HY; Wu S; Meno-Tetang G; Shah DK
J Pharmacokinet Pharmacodyn; 2019 Aug; 46(4):319-338. PubMed ID: 31115858
[TBL] [Abstract][Full Text] [Related]
15. Computer-assembled cross-species/cross-modalities two-pore physiologically based pharmacokinetic model for biologics in mice and rats.
Sepp A; Meno-Tetang G; Weber A; Sanderson A; Schon O; Berges A
J Pharmacokinet Pharmacodyn; 2019 Aug; 46(4):339-359. PubMed ID: 31079322
[TBL] [Abstract][Full Text] [Related]
16. Multiscale Modeling of Antibody-Drug Conjugates: Connecting Tissue and Cellular Distribution to Whole Animal Pharmacokinetics and Potential Implications for Efficacy.
Cilliers C; Guo H; Liao J; Christodolu N; Thurber GM
AAPS J; 2016 Sep; 18(5):1117-1130. PubMed ID: 27287046
[TBL] [Abstract][Full Text] [Related]
17. Physiologically based pharmacokinetic model for specific and nonspecific monoclonal antibodies and fragments in normal tissues and human tumor xenografts in nude mice.
Baxter LT; Zhu H; Mackensen DG; Jain RK
Cancer Res; 1994 Mar; 54(6):1517-28. PubMed ID: 8137258
[TBL] [Abstract][Full Text] [Related]
18. Development of a physiologically-based pharmacokinetic model for ocular disposition of monoclonal antibodies in rabbits.
Bussing D; K Shah D
J Pharmacokinet Pharmacodyn; 2020 Dec; 47(6):597-612. PubMed ID: 32876799
[TBL] [Abstract][Full Text] [Related]
19. Antibody biodistribution coefficients: inferring tissue concentrations of monoclonal antibodies based on the plasma concentrations in several preclinical species and human.
Shah DK; Betts AM
MAbs; 2013; 5(2):297-305. PubMed ID: 23406896
[TBL] [Abstract][Full Text] [Related]
20. Population PBPK modelling of trastuzumab: a framework for quantifying and predicting inter-individual variability.
Malik PRV; Hamadeh A; Phipps C; Edginton AN
J Pharmacokinet Pharmacodyn; 2017 Jun; 44(3):277-290. PubMed ID: 28260166
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
