203 related articles for article (PubMed ID: 34146544)
1. mTORC1 activation is not sufficient to suppress hepatic PPARα signaling or ketogenesis.
Selen ES; Wolfgang MJ
J Biol Chem; 2021 Jul; 297(1):100884. PubMed ID: 34146544
[TBL] [Abstract][Full Text] [Related]
2. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.
Sengupta S; Peterson TR; Laplante M; Oh S; Sabatini DM
Nature; 2010 Dec; 468(7327):1100-4. PubMed ID: 21179166
[TBL] [Abstract][Full Text] [Related]
3. Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21.
Cornu M; Oppliger W; Albert V; Robitaille AM; Trapani F; Quagliata L; Fuhrer T; Sauer U; Terracciano L; Hall MN
Proc Natl Acad Sci U S A; 2014 Aug; 111(32):11592-9. PubMed ID: 25082895
[TBL] [Abstract][Full Text] [Related]
4. The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex.
Wu R; Dang F; Li P; Wang P; Xu Q; Liu Z; Li Y; Wu Y; Chen Y; Liu Y
Cell Metab; 2019 Mar; 29(3):653-667.e6. PubMed ID: 30527742
[TBL] [Abstract][Full Text] [Related]
5. Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling.
de la Calle Arregui C; Plata-Gómez AB; Deleyto-Seldas N; García F; Ortega-Molina A; Abril-Garrido J; Rodriguez E; Nemazanyy I; Tribouillard L; de Martino A; Caleiras E; Campos-Olivas R; Mulero F; Laplante M; Muñoz J; Pende M; Sabio G; Sabatini DM; Efeyan A
Nat Commun; 2021 Jun; 12(1):3660. PubMed ID: 34135321
[TBL] [Abstract][Full Text] [Related]
6. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex.
Wang Y; Tang S; Wu Y; Wan X; Zhou M; Li H; Zha X
IUBMB Life; 2020 May; 72(5):965-977. PubMed ID: 31958214
[TBL] [Abstract][Full Text] [Related]
7. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders.
Leone TC; Weinheimer CJ; Kelly DP
Proc Natl Acad Sci U S A; 1999 Jun; 96(13):7473-8. PubMed ID: 10377439
[TBL] [Abstract][Full Text] [Related]
8. The specificity and role of microglia in epileptogenesis in mouse models of tuberous sclerosis complex.
Zhang B; Zou J; Han L; Beeler B; Friedman JL; Griffin E; Piao YS; Rensing NR; Wong M
Epilepsia; 2018 Sep; 59(9):1796-1806. PubMed ID: 30079598
[TBL] [Abstract][Full Text] [Related]
9. Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
Haji N; Riebe I; Aguilar-Valles A; Artinian J; Laplante I; Lacaille JC
Mol Autism; 2020 May; 11(1):29. PubMed ID: 32375878
[TBL] [Abstract][Full Text] [Related]
10. Osteocyte TSC1 promotes sclerostin secretion to restrain osteogenesis in mice.
Liu W; Wang Z; Yang J; Wang Y; Li K; Huang B; Yan B; Wang T; Li M; Zou Z; Yang J; Xiao G; Cui ZK; Liu A; Bai X
Open Biol; 2019 May; 9(5):180262. PubMed ID: 31088250
[TBL] [Abstract][Full Text] [Related]
11. TSC1 deletion in fibroblasts alleviates lipopolysaccharide-induced acute kidney injury.
Shen J; Cui ZK; Yao F; Li K; Zhang Y; Chen Z; Zhou Y; Xu S; Zhang Y; Jiang W; Zhang H; Tan K; Liu A; Bai X
Clin Sci (Lond); 2018 Oct; 132(19):2087-2101. PubMed ID: 30185506
[TBL] [Abstract][Full Text] [Related]
12. Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss.
Fu X; Sun X; Zhang L; Jin Y; Chai R; Yang L; Zhang A; Liu X; Bai X; Li J; Wang H; Gao J
J Clin Invest; 2018 Nov; 128(11):4938-4955. PubMed ID: 30247156
[TBL] [Abstract][Full Text] [Related]
13. Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice.
Cotter DG; Ercal B; d'Avignon DA; Dietzen DJ; Crawford PA
Am J Physiol Endocrinol Metab; 2014 Jul; 307(2):E176-85. PubMed ID: 24865983
[TBL] [Abstract][Full Text] [Related]
14. Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy.
Chao X; Wang S; Fulte S; Ma X; Ahamed F; Cui W; Liu Z; Rülicke T; Zatloukal K; Zong WX; Liu W; Ni HM; Ding WX
J Hepatol; 2022 Mar; 76(3):639-651. PubMed ID: 34710483
[TBL] [Abstract][Full Text] [Related]
15. Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma.
Hartleben G; Müller C; Krämer A; Schimmel H; Zidek LM; Dornblut C; Winkler R; Eichwald S; Kortman G; Kosan C; Kluiver J; Petersen I; van den Berg A; Wang ZQ; Calkhoven CF
EMBO J; 2018 Nov; 37(21):. PubMed ID: 30237309
[TBL] [Abstract][Full Text] [Related]
16. Constitutive Activation of the Nutrient Sensor mTORC1 in Myeloid Cells Induced by Tsc1 Deletion Protects Mice from Diet-Induced Obesity.
Paschoal VA; Belchior T; Amano MT; Burgos-Silva M; Peixoto AS; Magdalon J; Vieira TS; Andrade ML; Moreno MF; Chimin P; Câmara NO; Festuccia WT
Mol Nutr Food Res; 2018 Sep; 62(17):e1800283. PubMed ID: 30001482
[TBL] [Abstract][Full Text] [Related]
17. Hyperactivation of mTORC1 disrupts cellular homeostasis in cerebellar Purkinje cells.
Sakai Y; Kassai H; Nakayama H; Fukaya M; Maeda T; Nakao K; Hashimoto K; Sakagami H; Kano M; Aiba A
Sci Rep; 2019 Feb; 9(1):2799. PubMed ID: 30808980
[TBL] [Abstract][Full Text] [Related]
18. Constitutive adipocyte mTORC1 activation enhances mitochondrial activity and reduces visceral adiposity in mice.
Magdalon J; Chimin P; Belchior T; Neves RX; Vieira-Lara MA; Andrade ML; Farias TS; Bolsoni-Lopes A; Paschoal VA; Yamashita AS; Kowaltowski AJ; Festuccia WT
Biochim Biophys Acta; 2016 May; 1861(5):430-8. PubMed ID: 26923434
[TBL] [Abstract][Full Text] [Related]
19. MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Yang H; Wen Y; Zhang M; Liu Q; Zhang H; Zhang J; Lu L; Ye T; Bai X; Xiao G; Wang M
Autophagy; 2020 Feb; 16(2):271-288. PubMed ID: 31007149
[TBL] [Abstract][Full Text] [Related]
20. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting.
Kersten S; Seydoux J; Peters JM; Gonzalez FJ; Desvergne B; Wahli W
J Clin Invest; 1999 Jun; 103(11):1489-98. PubMed ID: 10359558
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
