BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 34146702)

  • 1. Synthesis of NVS-BPTF-1 and evaluation of its biological activity.
    Mélin L; Calosing C; Kharenko OA; Hansen HC; Gagnon A
    Bioorg Med Chem Lett; 2021 Sep; 47():128208. PubMed ID: 34146702
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New Design Rules for Developing Potent Cell-Active Inhibitors of the Nucleosome Remodeling Factor (NURF) via BPTF Bromodomain Inhibition.
    Zahid H; Buchholz CR; Singh M; Ciccone MF; Chan A; Nithianantham S; Shi K; Aihara H; Fischer M; Schönbrunn E; Dos Santos CO; Landry JW; Pomerantz WCK
    J Med Chem; 2021 Sep; 64(18):13902-13917. PubMed ID: 34515477
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BPTF Depletion Enhances T-cell-Mediated Antitumor Immunity.
    Mayes K; Alkhatib SG; Peterson K; Alhazmi A; Song C; Chan V; Blevins T; Roberts M; Dumur CI; Wang XY; Landry JW
    Cancer Res; 2016 Nov; 76(21):6183-6192. PubMed ID: 27651309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
    Ycas PD; Zahid H; Chan A; Olson NM; Johnson JA; Talluri SK; Schonbrunn E; Pomerantz WCK
    Org Biomol Chem; 2020 Jul; 18(27):5174-5182. PubMed ID: 32588860
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization.
    Xiong L; Mao X; Guo Y; Zhou Y; Chen M; Chen P; Yang S; Li L
    Biochem Biophys Res Commun; 2021 Mar; 545():125-131. PubMed ID: 33548625
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor.
    Kirberger SE; Ycas PD; Johnson JA; Chen C; Ciccone MF; Woo RWL; Urick AK; Zahid H; Shi K; Aihara H; McAllister SD; Kashani-Sabet M; Shi J; Dickson A; Dos Santos CO; Pomerantz WCK
    Org Biomol Chem; 2019 Feb; 17(7):2020-2027. PubMed ID: 30706071
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Opportunity knocks for uncovering the new function of an understudied nucleosome remodeling complex member, the bromodomain PHD finger transcription factor, BPTF.
    Zahid H; Olson NM; Pomerantz WCK
    Curr Opin Chem Biol; 2021 Aug; 63():57-67. PubMed ID: 33706239
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Compound C620-0696, a new potent inhibitor targeting BPTF, the chromatin-remodeling factor in non-small-cell lung cancer.
    Xu J; Wang Q; Leung ELH; Li Y; Fan X; Wu Q; Yao X; Liu L
    Front Med; 2020 Feb; 14(1):60-67. PubMed ID: 31104301
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Haploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features.
    Stankiewicz P; Khan TN; Szafranski P; Slattery L; Streff H; Vetrini F; Bernstein JA; Brown CW; Rosenfeld JA; Rednam S; Scollon S; Bergstrom KL; Parsons DW; Plon SE; Vieira MW; Quaio CRDC; Baratela WAR; Acosta Guio JC; Armstrong R; Mehta SG; Rump P; Pfundt R; Lewandowski R; Fernandes EM; Shinde DN; Tang S; Hoyer J; Zweier C; Reis A; Bacino CA; Xiao R; Breman AM; Smith JL; ; Katsanis N; Bostwick B; Popp B; Davis EE; Yang Y
    Am J Hum Genet; 2017 Oct; 101(4):503-515. PubMed ID: 28942966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Chromatin Remodeler BPTF Activates a Stemness Gene-Expression Program Essential for the Maintenance of Adult Hematopoietic Stem Cells.
    Xu B; Cai L; Butler JM; Chen D; Lu X; Allison DF; Lu R; Rafii S; Parker JS; Zheng D; Wang GG
    Stem Cell Reports; 2018 Mar; 10(3):675-683. PubMed ID: 29456179
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.
    Landry J; Sharov AA; Piao Y; Sharova LV; Xiao H; Southon E; Matta J; Tessarollo L; Zhang YE; Ko MS; Kuehn MR; Yamaguchi TP; Wu C
    PLoS Genet; 2008 Oct; 4(10):e1000241. PubMed ID: 18974875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening.
    Zhang D; Han J; Lu W; Lian F; Wang J; Lu T; Tao H; Xiao S; Zhang F; Liu YC; Liu R; Zhang N; Jiang H; Chen K; Zhao C; Luo C
    Bioorg Chem; 2019 May; 86():494-500. PubMed ID: 30780018
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
    Li H; Ilin S; Wang W; Duncan EM; Wysocka J; Allis CD; Patel DJ
    Nature; 2006 Jul; 442(7098):91-5. PubMed ID: 16728978
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain.
    Lu T; Lu H; Duan Z; Wang J; Han J; Xiao S; Chen H; Jiang H; Chen Y; Yang F; Li Q; Chen D; Lin J; Li B; Jiang H; Chen K; Lu W; Lin H; Luo C
    J Med Chem; 2021 Aug; 64(16):12075-12088. PubMed ID: 34375106
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma.
    Zhang C; Chen L; Liu Y; Huang J; Liu A; Xu Y; Shen Y; He H; Xu D
    Theranostics; 2021; 11(8):3676-3693. PubMed ID: 33664855
    [No Abstract]   [Full Text] [Related]  

  • 16. Upregulation of bromodomain PHD finger transcription factor in ovarian cancer and its critical role for cancer cell proliferation and survival.
    Miao J; Zhang M; Huang X; Xu L; Tang R; Wang H; Han S
    Biochem Cell Biol; 2021 Jun; 99(3):304-312. PubMed ID: 32985220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments.
    Martinelli P; Schaaf O; Mantoulidis A; Martin LJ; Fuchs JE; Bader G; Gollner A; Wolkerstorfer B; Rogers C; Balıkçı E; Lipp JJ; Mischerikow N; Doebel S; Gerstberger T; Sommergruber W; Huber KVM; Böttcher J
    ChemMedChem; 2023 Mar; 18(6):e202200686. PubMed ID: 36649575
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bromodomain inhibition targeting BPTF in the treatment of melanoma and other solid tumors.
    Khan I; Kashani-Sabet M
    Clin Exp Metastasis; 2024 Apr; ():. PubMed ID: 38683257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.
    Zhao X; Zheng F; Li Y; Hao J; Tang Z; Tian C; Yang Q; Zhu T; Diao C; Zhang C; Chen M; Hu S; Guo P; Zhang L; Liao Y; Yu W; Chen M; Zou L; Guo W; Deng W
    Redox Biol; 2019 Jan; 20():427-441. PubMed ID: 30419422
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor.
    Tyutyunyk-Massey L; Sun Y; Dao N; Ngo H; Dammalapati M; Vaidyanathan A; Singh M; Haqqani S; Haueis J; Finnegan R; Deng X; Kirberger SE; Bos PD; Bandyopadhyay D; Pomerantz WCK; Pommier Y; Gewirtz DA; Landry JW
    Mol Cancer Res; 2021 Aug; 19(8):1338-1349. PubMed ID: 33811160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.