146 related articles for article (PubMed ID: 34152652)
1. Novel variants of engineered water soluble mu opioid receptors with extensive mutations and removal of cysteines.
Xi J; Yang N; Perez-Aguilar JM; Selling B; Grothusen JR; Lamichhane R; Saven JG; Liu R
Proteins; 2021 Oct; 89(10):1386-1393. PubMed ID: 34152652
[TBL] [Abstract][Full Text] [Related]
2. Characterization of an engineered water-soluble variant of the full-length human mu opioid receptor.
Xi J; Xiao J; Perez-Aguilar JM; Ping J; Johnson ATC; Saven JG; Liu R
J Biomol Struct Dyn; 2020 Sep; 38(14):4364-4370. PubMed ID: 31588852
[TBL] [Abstract][Full Text] [Related]
3. A computationally designed water-soluble variant of a G-protein-coupled receptor: the human mu opioid receptor.
Perez-Aguilar JM; Xi J; Matsunaga F; Cui X; Selling B; Saven JG; Liu R
PLoS One; 2013; 8(6):e66009. PubMed ID: 23799068
[TBL] [Abstract][Full Text] [Related]
4. Characterization of a computationally designed water-soluble human μ-opioid receptor variant using available structural information.
Zhao X; Perez-Aguilar JM; Matsunaga F; Lerner M; Xi J; Selling B; Johnson AT; Saven JG; Liu R
Anesthesiology; 2014 Oct; 121(4):866-75. PubMed ID: 24835677
[TBL] [Abstract][Full Text] [Related]
5. A Truncated Six Transmembrane Splice Variant MOR-1G Enhances Expression of the Full-Length Seven Transmembrane
Zhang T; Xu J; Pan YX
Mol Pharmacol; 2020 Oct; 98(4):518-527. PubMed ID: 32723770
[TBL] [Abstract][Full Text] [Related]
6. Refinement of a homology model of the mu-opioid receptor using distance constraints from intrinsic and engineered zinc-binding sites.
Fowler CB; Pogozheva ID; LeVine H; Mosberg HI
Biochemistry; 2004 Jul; 43(27):8700-10. PubMed ID: 15236578
[TBL] [Abstract][Full Text] [Related]
7. Mu Opioids Induce Biased Signaling at the Full-Length Seven Transmembrane C-Terminal Splice Variants of the mu Opioid Receptor Gene, Oprm1.
Narayan A; Hunkele A; Xu J; Bassoni DL; Pasternak GW; Pan YX
Cell Mol Neurobiol; 2021 Jul; 41(5):1059-1074. PubMed ID: 33033993
[TBL] [Abstract][Full Text] [Related]
8. The C-terminus of the mu opioid receptor is critical in G-protein interaction as demonstrated by a novel graphene biosensor.
Wen C; Selling B; Yeliseev A; Xi J; Perez-Aguilar JM; Gao Z; Saven JG; Johnson ATC; Liu R
IEEE Sens J; 2021 Mar; 21(5):5758-5762. PubMed ID: 33679256
[TBL] [Abstract][Full Text] [Related]
9. Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon.
Doyle GA; Sheng XR; Lin SS; Press DM; Grice DE; Buono RJ; Ferraro TN; Berrettini WH
Gene; 2007 Jun; 395(1-2):98-107. PubMed ID: 17398041
[TBL] [Abstract][Full Text] [Related]
10. The opioid ligand binding of human mu-opioid receptor is modulated by novel splice variants of the receptor.
Choi HS; Kim CS; Hwang CK; Song KY; Wang W; Qiu Y; Law PY; Wei LN; Loh HH
Biochem Biophys Res Commun; 2006 May; 343(4):1132-40. PubMed ID: 16580639
[TBL] [Abstract][Full Text] [Related]
11. Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias.
Hothersall JD; Torella R; Humphreys S; Hooley M; Brown A; McMurray G; Nickolls SA
Neuropharmacology; 2017 May; 118():46-58. PubMed ID: 28283391
[TBL] [Abstract][Full Text] [Related]
12. To probe interaction of morphine and IBNtxA with 7TM and 6TM variants of the human μ-opioid receptor using all-atom molecular dynamics simulations with an explicit membrane.
Sader S; Anant K; Wu C
Phys Chem Chem Phys; 2018 Jan; 20(3):1724-1741. PubMed ID: 29265141
[TBL] [Abstract][Full Text] [Related]
13. Comparison of the amino acid residues in the sixth transmembrane domains accessible in the binding-site crevices of mu, delta, and kappa opioid receptors.
Xu W; Li J; Chen C; Huang P; Weinstein H; Javitch JA; Shi L; de Riel JK; Liu-Chen LY
Biochemistry; 2001 Jul; 40(27):8018-29. PubMed ID: 11434771
[TBL] [Abstract][Full Text] [Related]
14. mu Opioid receptor: role for the amino terminus as a determinant of ligand binding affinity.
Chaturvedi K; Shahrestanifar M; Howells RD
Brain Res Mol Brain Res; 2000 Mar; 76(1):64-72. PubMed ID: 10719216
[TBL] [Abstract][Full Text] [Related]
15. The local environment at the cytoplasmic end of TM6 of the mu opioid receptor differs from those of rhodopsin and monoamine receptors: introduction of an ionic lock between the cytoplasmic ends of helices 3 and 6 by a L6.30(275)E mutation inactivates the mu opioid receptor and reduces the constitutive activity of its T6.34(279)K mutant.
Huang P; Visiers I; Weinstein H; Liu-Chen LY
Biochemistry; 2002 Oct; 41(40):11972-80. PubMed ID: 12356297
[TBL] [Abstract][Full Text] [Related]
16. Mutation of human mu opioid receptor extracellular "disulfide cysteine" residues alters ligand binding but does not prevent receptor targeting to the cell plasma membrane.
Zhang P; Johnson PS; Zöllner C; Wang W; Wang Z; Montes AE; Seidleck BK; Blaschak CJ; Surratt CK
Brain Res Mol Brain Res; 1999 Oct; 72(2):195-204. PubMed ID: 10529478
[TBL] [Abstract][Full Text] [Related]
17. Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene.
Pan YX; Xu J; Mahurter L; Bolan E; Xu M; Pasternak GW
Proc Natl Acad Sci U S A; 2001 Nov; 98(24):14084-9. PubMed ID: 11717463
[TBL] [Abstract][Full Text] [Related]
18. Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.
Xu J; Xu M; Bolan E; Gilbert AK; Pasternak GW; Pan YX
Synapse; 2014 Apr; 68(4):144-52. PubMed ID: 24375714
[TBL] [Abstract][Full Text] [Related]
19. Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.
Majumdar S; Grinnell S; Le Rouzic V; Burgman M; Polikar L; Ansonoff M; Pintar J; Pan YX; Pasternak GW
Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19778-83. PubMed ID: 22106286
[TBL] [Abstract][Full Text] [Related]
20. Identification and characterization of six new alternatively spliced variants of the human mu opioid receptor gene, Oprm.
Pan L; Xu J; Yu R; Xu MM; Pan YX; Pasternak GW
Neuroscience; 2005; 133(1):209-20. PubMed ID: 15893644
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
