BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 34155194)

  • 1. Phenotypic manifestation of α-synuclein strains derived from Parkinson's disease and multiple system atrophy in human dopaminergic neurons.
    Tanudjojo B; Shaikh SS; Fenyi A; Bousset L; Agarwal D; Marsh J; Zois C; Heman-Ackah S; Fischer R; Sims D; Melki R; Tofaris GK
    Nat Commun; 2021 Jun; 12(1):3817. PubMed ID: 34155194
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease.
    Sharma N; Rao SP; Kalivendi SV
    Free Radic Biol Med; 2019 May; 135():28-37. PubMed ID: 30796974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Parkinson's disease-related protein DJ-1 protects dopaminergic neurons in vivo and cultured cells from alpha-synuclein and 6-hydroxydopamine toxicity.
    Batelli S; Invernizzi RW; Negro A; Calcagno E; Rodilossi S; Forloni G; Albani D
    Neurodegener Dis; 2015; 15(1):13-23. PubMed ID: 25500798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
    Pujols J; Peña-Díaz S; Lázaro DF; Peccati F; Pinheiro F; González D; Carija A; Navarro S; Conde-Giménez M; García J; Guardiola S; Giralt E; Salvatella X; Sancho J; Sodupe M; Outeiro TF; Dalfó E; Ventura S
    Proc Natl Acad Sci U S A; 2018 Oct; 115(41):10481-10486. PubMed ID: 30249646
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.
    Wegrzynowicz M; Bar-On D; Calo' L; Anichtchik O; Iovino M; Xia J; Ryazanov S; Leonov A; Giese A; Dalley JW; Griesinger C; Ashery U; Spillantini MG
    Acta Neuropathol; 2019 Oct; 138(4):575-595. PubMed ID: 31165254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Initiation and propagation of α-synuclein aggregation in the nervous system.
    Hijaz BA; Volpicelli-Daley LA
    Mol Neurodegener; 2020 Mar; 15(1):19. PubMed ID: 32143659
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Brain alpha-synuclein accumulation in multiple system atrophy, Parkinson's disease and progressive supranuclear palsy: a comparative investigation.
    Tong J; Wong H; Guttman M; Ang LC; Forno LS; Shimadzu M; Rajput AH; Muenter MD; Kish SJ; Hornykiewicz O; Furukawa Y
    Brain; 2010 Jan; 133(Pt 1):172-88. PubMed ID: 19903734
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CD8 T cell nigral infiltration precedes synucleinopathy in early stages of Parkinson's disease.
    Galiano-Landeira J; Torra A; Vila M; Bové J
    Brain; 2020 Dec; 143(12):3717-3733. PubMed ID: 33118032
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts.
    Strohäker T; Jung BC; Liou SH; Fernandez CO; Riedel D; Becker S; Halliday GM; Bennati M; Kim WS; Lee SJ; Zweckstetter M
    Nat Commun; 2019 Dec; 10(1):5535. PubMed ID: 31797870
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson's Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology.
    Diao X; Wang F; Becerra-Calixto A; Soto C; Mukherjee A
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572052
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion
    Nakamura Y; Arawaka S; Sato H; Sasaki A; Shigekiyo T; Takahata K; Tsunekawa H; Kato T
    J Neurosci; 2021 Sep; 41(35):7479-7491. PubMed ID: 34290084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC.
    Palazzi L; Fongaro B; Leri M; Acquasaliente L; Stefani M; Bucciantini M; Polverino de Laureto P
    Int J Mol Sci; 2021 Jun; 22(11):. PubMed ID: 34199427
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Parkinson's disease risk genes act in glia to control neuronal α-synuclein toxicity.
    Olsen AL; Feany MB
    Neurobiol Dis; 2021 Nov; 159():105482. PubMed ID: 34390834
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy.
    Lövestam S; Schweighauser M; Matsubara T; Murayama S; Tomita T; Ando T; Hasegawa K; Yoshida M; Tarutani A; Hasegawa M; Goedert M; Scheres SHW
    FEBS Open Bio; 2021 Apr; 11(4):999-1013. PubMed ID: 33548114
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Alpha-Synuclein RT-QuIC Products Generated by the Olfactory Mucosa of Patients with Parkinson's Disease and Multiple System Atrophy Induce Inflammatory Responses in SH-SY5Y Cells.
    De Luca CMG; Consonni A; Cazzaniga FA; Bistaffa E; Bufano G; Quitarrini G; Celauro L; Legname G; Eleopra R; Baggi F; Giaccone G; Moda F
    Cells; 2021 Dec; 11(1):. PubMed ID: 35011649
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Somatic copy number gains of α-synuclein (SNCA) in Parkinson's disease and multiple system atrophy brains.
    Mokretar K; Pease D; Taanman JW; Soenmez A; Ejaz A; Lashley T; Ling H; Gentleman S; Houlden H; Holton JL; Schapira AHV; Nacheva E; Proukakis C
    Brain; 2018 Aug; 141(8):2419-2431. PubMed ID: 29917054
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DJ-1, a Parkinson's disease related protein, aggregates under denaturing conditions and co-aggregates with α-synuclein through hydrophobic interaction.
    Zhu M; H Patel S; Han S
    Biochim Biophys Acta Gen Subj; 2017 Jul; 1861(7):1759-1769. PubMed ID: 28330770
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity.
    Kim H; Calatayud C; Guha S; Fernández-Carasa I; Berkowitz L; Carballo-Carbajal I; Ezquerra M; Fernández-Santiago R; Kapahi P; Raya Á; Miranda-Vizuete A; Lizcano JM; Vila M; Caldwell KA; Caldwell GA; Consiglio A; Dalfo E
    Mol Neurobiol; 2018 Sep; 55(9):7533-7552. PubMed ID: 29429047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
    Fukusumi H; Togo K; Sumida M; Nakamori M; Obika S; Baba K; Shofuda T; Ito D; Okano H; Mochizuki H; Kanemura Y
    FEBS Open Bio; 2021 Feb; 11(2):354-366. PubMed ID: 33301617
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein mimetic 2D FAST rescues alpha synuclein aggregation mediated early and post disease Parkinson's phenotypes.
    Stillman NH; Joseph JA; Ahmed J; Baysah CZ; Dohoney RA; Ball TD; Thomas AG; Fitch TC; Donnelly CM; Kumar S
    Nat Commun; 2024 Apr; 15(1):3658. PubMed ID: 38688913
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.