BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 34156324)

  • 1. Activation of CDC25A phosphatase is limited by CDK2/cyclin A-mediated feedback inhibition.
    Ditano JP; Sakurikar N; Eastman A
    Cell Cycle; 2021 Jul; 20(13):1308-1319. PubMed ID: 34156324
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase.
    Sakurikar N; Thompson R; Montano R; Eastman A
    Oncotarget; 2016 Jan; 7(2):1380-94. PubMed ID: 26595527
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of Chk1-Cdc25A-cyclin A/CDK2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells.
    Tu YS; Kang XL; Zhou JG; Lv XF; Tang YB; Guan YY
    Eur J Pharmacol; 2011 Nov; 670(2-3):356-64. PubMed ID: 21958871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine.
    Sampath D; Shi Z; Plunkett W
    Mol Pharmacol; 2002 Sep; 62(3):680-8. PubMed ID: 12181445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.
    Sandhu C; Donovan J; Bhattacharya N; Stampfer M; Worland P; Slingerland J
    Oncogene; 2000 Nov; 19(47):5314-23. PubMed ID: 11103932
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.
    Jin J; Shirogane T; Xu L; Nalepa G; Qin J; Elledge SJ; Harper JW
    Genes Dev; 2003 Dec; 17(24):3062-74. PubMed ID: 14681206
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effects of over-expression and suppression of Cdc25A on the S-phase checkpoint induced by benzo(a)pyrene.
    Yao B; Fu J; Hu E; Qi Y; Zhou Z
    Toxicology; 2008 Apr; 246(2-3):180-7. PubMed ID: 18321631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases.
    Blomberg I; Hoffmann I
    Mol Cell Biol; 1999 Sep; 19(9):6183-94. PubMed ID: 10454565
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition.
    Hoffmann I; Draetta G; Karsenti E
    EMBO J; 1994 Sep; 13(18):4302-10. PubMed ID: 7523110
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry.
    Mazzolini L; Broban A; Froment C; Burlet-Schiltz O; Besson A; Manenti S; Dozier C
    Cell Cycle; 2016 Oct; 15(20):2742-52. PubMed ID: 27580187
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism.
    Liu P; Barkley LR; Day T; Bi X; Slater DM; Alexandrow MG; Nasheuer HP; Vaziri C
    J Biol Chem; 2006 Oct; 281(41):30631-44. PubMed ID: 16912045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA damage-induced degradation of Cdc25A does not lead to inhibition of Cdk2 activity in mouse embryonic stem cells.
    Koledova Z; Kafkova LR; Krämer A; Divoky V
    Stem Cells; 2010 Mar; 28(3):450-61. PubMed ID: 20104581
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NEK11: linking CHK1 and CDC25A in DNA damage checkpoint signaling.
    Sørensen CS; Melixetian M; Klein DK; Helin K
    Cell Cycle; 2010 Feb; 9(3):450-5. PubMed ID: 20090422
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human Cdc25A phosphatase has a non-redundant function in G2 phase by activating Cyclin A-dependent kinases.
    Timofeev O; Cizmecioglu O; Hu E; Orlik T; Hoffmann I
    FEBS Lett; 2009 Feb; 583(4):841-7. PubMed ID: 19192479
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Serine-Threonine Kinase 38 regulates CDC25A stability and the DNA damage-induced G2/M checkpoint.
    Fukasawa T; Enomoto A; Miyagawa K
    Cell Signal; 2015 Aug; 27(8):1569-75. PubMed ID: 25936524
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of the ATR-CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2.
    Koppenhafer SL; Goss KL; Terry WW; Gordon DJ
    Mol Cancer Res; 2020 Jan; 18(1):91-104. PubMed ID: 31649026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdk2 is required for p53-independent G2/M checkpoint control.
    Chung JH; Bunz F
    PLoS Genet; 2010 Feb; 6(2):e1000863. PubMed ID: 20195506
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint.
    Melixetian M; Klein DK; Sørensen CS; Helin K
    Nat Cell Biol; 2009 Oct; 11(10):1247-53. PubMed ID: 19734889
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclin A/Cdk2 regulates Cdh1 and claspin during late S/G2 phase of the cell cycle.
    Oakes V; Wang W; Harrington B; Lee WJ; Beamish H; Chia KM; Pinder A; Goto H; Inagaki M; Pavey S; Gabrielli B
    Cell Cycle; 2014; 13(20):3302-11. PubMed ID: 25485510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aberrant activation of cyclin A-CDK induces G2/M-phase checkpoint in human cells.
    Akaike Y; Chibazakura T
    Cell Cycle; 2020 Jan; 19(1):84-96. PubMed ID: 31760882
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.