BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 34157286)

  • 1. Molecular determinants for α-tubulin methylation by SETD2.
    Kearns S; Mason FM; Rathmell WK; Park IY; Walker C; Verhey KJ; Cianfrocco MA
    J Biol Chem; 2021 Jul; 297(1):100898. PubMed ID: 34157286
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual Chromatin and Cytoskeletal Remodeling by SETD2.
    Park IY; Powell RT; Tripathi DN; Dere R; Ho TH; Blasius TL; Chiang YC; Davis IJ; Fahey CC; Hacker KE; Verhey KJ; Bedford MT; Jonasch E; Rathmell WK; Walker CL
    Cell; 2016 Aug; 166(4):950-962. PubMed ID: 27518565
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice.
    Koenning M; Wang X; Karki M; Jangid RK; Kearns S; Tripathi DN; Cianfrocco M; Verhey KJ; Jung SY; Coarfa C; Ward CS; Kalish BT; Grimm SL; Rathmell WK; Mostany R; Dere R; Rasband MN; Walker CL; Park IY
    Brain; 2021 Sep; 144(8):2527-2540. PubMed ID: 34014281
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation.
    Hacker KE; Fahey CC; Shinsky SA; Chiang YJ; DiFiore JV; Jha DK; Vo AH; Shavit JA; Davis IJ; Strahl BD; Rathmell WK
    J Biol Chem; 2016 Sep; 291(40):21283-21295. PubMed ID: 27528607
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A New Chromatin-Cytoskeleton Link in Cancer.
    Giaccia AJ
    Mol Cancer Res; 2016 Dec; 14(12):1173-1175. PubMed ID: 27528705
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The microtubule-associated histone methyltransferase SET8, facilitated by transcription factor LSF, methylates α-tubulin.
    Chin HG; Esteve PO; Ruse C; Lee J; Schaus SE; Pradhan S; Hansen U
    J Biol Chem; 2020 Apr; 295(14):4748-4759. PubMed ID: 32111740
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methylated α-tubulin antibodies recognize a new microtubule modification on mitotic microtubules.
    Park IY; Chowdhury P; Tripathi DN; Powell RT; Dere R; Terzo EA; Rathmell WK; Walker CL
    MAbs; 2016; 8(8):1590-1597. PubMed ID: 27594515
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and enzymatic evidence for the methylation of the ACK1 tyrosine kinase by the histone lysine methyltransferase SETD2.
    Le Coadou L; Berthelet J; Mechaly AE; Michail C; Bui LC; Dairou J; Haouz A; Dupret JM; Rodrigues Lima F
    Biochem Biophys Res Commun; 2024 Feb; 695():149400. PubMed ID: 38160530
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation.
    Zhang Y; Shan CM; Wang J; Bao K; Tong L; Jia S
    Sci Rep; 2017 Mar; 7():43906. PubMed ID: 28256625
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3).
    Berthelet J; Michail C; Bui LC; Le Coadou L; Sirri V; Wang L; Dulphy N; Dupret JM; Chomienne C; Guidez F; Rodrigues-Lima F
    Mol Pharmacol; 2021 Sep; 100(3):283-294. PubMed ID: 34266924
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation.
    Fahey CC; Davis IJ
    Cold Spring Harb Perspect Med; 2017 May; 7(5):. PubMed ID: 28159833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. α-TubK40me3 is required for neuronal polarization and migration by promoting microtubule formation.
    Xie X; Wang S; Li M; Diao L; Pan X; Chen J; Zou W; Zhang X; Feng W; Bao L
    Nat Commun; 2021 Jul; 12(1):4113. PubMed ID: 34226540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A missense SNP in the tumor suppressor SETD2 reduces H3K36me3 and mitotic spindle integrity in Drosophila.
    Brockett JS; Manalo T; Zein-Sabatto H; Lee J; Fang J; Chu P; Feng H; Patil D; Davidson P; Ogan K; Master VA; Pattaras JG; Roberts DL; Bergquist SH; Reyna MA; Petros JA; Lerit DA; Arnold RS
    Genetics; 2024 Apr; 226(4):. PubMed ID: 38290049
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SETD2: from chromatin modifier to multipronged regulator of the genome and beyond.
    Molenaar TM; van Leeuwen F
    Cell Mol Life Sci; 2022 Jun; 79(6):346. PubMed ID: 35661267
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Shaping the cellular landscape with Set2/SETD2 methylation.
    McDaniel SL; Strahl BD
    Cell Mol Life Sci; 2017 Sep; 74(18):3317-3334. PubMed ID: 28386724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The disordered regions of the methyltransferase SETD2 govern its function by regulating its proteolysis and phase separation.
    Bhattacharya S; Lange JJ; Levy M; Florens L; Washburn MP; Workman JL
    J Biol Chem; 2021 Sep; 297(3):101075. PubMed ID: 34391778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase.
    Yang S; Zheng X; Lu C; Li GM; Allis CD; Li H
    Genes Dev; 2016 Jul; 30(14):1611-6. PubMed ID: 27474439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate.
    Schuhmacher MK; Beldar S; Khella MS; Bröhm A; Ludwig J; Tempel W; Weirich S; Min J; Jeltsch A
    Commun Biol; 2020 Sep; 3(1):511. PubMed ID: 32939018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Automethylation of G9a and its implication in wider substrate specificity and HP1 binding.
    Chin HG; Estève PO; Pradhan M; Benner J; Patnaik D; Carey MF; Pradhan S
    Nucleic Acids Res; 2007; 35(21):7313-23. PubMed ID: 17962312
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Chiang YC; Park IY; Terzo EA; Tripathi DN; Mason FM; Fahey CC; Karki M; Shuster CB; Sohn BH; Chowdhury P; Powell RT; Ohi R; Tsai YS; de Cubas AA; Khan A; Davis IJ; Strahl BD; Parker JS; Dere R; Walker CL; Rathmell WK
    Cancer Res; 2018 Jun; 78(12):3135-3146. PubMed ID: 29724720
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.