BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 34157326)

  • 1. Astragaloside IV inhibits hepatocellular carcinoma by continually suppressing the development of fibrosis and regulating pSmad3C/3L and Nrf2/HO-1 pathways.
    Zhang C; Li L; Hou S; Shi Z; Xu W; Wang Q; He Y; Gong Y; Fang Z; Yang Y
    J Ethnopharmacol; 2021 Oct; 279():114350. PubMed ID: 34157326
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Astragaloside IV suppresses migration and invasion of TGF-β
    Li L; Wang Q; He Y; Sun L; Yang Y; Pang X
    Naunyn Schmiedebergs Arch Pharmacol; 2022 Apr; 395(4):397-405. PubMed ID: 35092472
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nrf2 knockout attenuates the astragaloside IV therapeutic effect on kidney fibrosis from liver cancer by regulating pSmad3C/3L pathways.
    Wang Q; Xu J; Li M; Chen Y; Xu Y; Li L; Gong Y; Yang Y
    Naunyn Schmiedebergs Arch Pharmacol; 2024 Mar; 397(3):1687-1700. PubMed ID: 37712971
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocellular carcinoma progression via miR-145/miR-21 mediated Smad3 phosphorylation.
    Wu C; Chen W; Fang M; Boye A; Tao X; Xu Y; Hou S; Yang Y
    J Ethnopharmacol; 2019 Mar; 231():98-112. PubMed ID: 30412748
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amelioratory effects of astragaloside IV on hepatocarcinogenesis via Nrf2-mediated pSmad3C/3L transformation.
    Fang Gong Y; Hou S; Xu JC; Chen Y; Zhu LL; Xu YY; Chen YQ; Li MM; Li LL; Yang JJ; Yang Y
    Phytomedicine; 2023 Aug; 117():154903. PubMed ID: 37301185
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Compound Astragalus and Salvia miltiorrhiza extracts modulate MAPK-regulated TGF-β/Smad signaling in hepatocellular carcinoma by multi-target mechanism.
    Boye A; Wu C; Jiang Y; Wang J; Wu J; Yang X; Yang Y
    J Ethnopharmacol; 2015 Jul; 169():219-28. PubMed ID: 25934513
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smad3 gene C-terminal phosphorylation site mutation exacerbates CCl
    Yang J; Gong Y; Xu W; Li L; Shi Z; Wang Q; He Y; Zhang C; Luo C; Fang Z; Yang Y
    Naunyn Schmiedebergs Arch Pharmacol; 2021 Aug; 394(8):1779-1786. PubMed ID: 34191114
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Compound Astragalus and Salvia miltiorrhiza extracts suppress hepatocarcinogenesis by modulating transforming growth factor-β/Smad signaling.
    Hu X; Rui W; Wu C; He S; Jiang J; Zhang X; Yang Y
    J Gastroenterol Hepatol; 2014 Jun; 29(6):1284-91. PubMed ID: 24329763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.
    Murata M; Matsuzaki K; Yoshida K; Sekimoto G; Tahashi Y; Mori S; Uemura Y; Sakaida N; Fujisawa J; Seki T; Kobayashi K; Yokote K; Koike K; Okazaki K
    Hepatology; 2009 Apr; 49(4):1203-17. PubMed ID: 19263472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of Nrf2/AREs-mediated antioxidant signalling, and suppression of profibrotic TGF-β1/Smad3 pathway: a promising therapeutic strategy for hepatic fibrosis - A review.
    Gong Y; Yang Y
    Life Sci; 2020 Sep; 256():117909. PubMed ID: 32512009
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Smad3 C-terminal phosphorylation site mutation attenuates the hepatoprotective effect of salvianolic acid B against hepatocarcinogenesis.
    Gong Y; Li D; Li L; Yang J; Ding H; Zhang C; Wen G; Wu C; Fang Z; Hou S; Yang Y
    Food Chem Toxicol; 2021 Jan; 147():111912. PubMed ID: 33290806
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21(WAF1) pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells.
    Li Q; Liu G; Yuan H; Wang J; Guo Y; Chen T; Zhai R; Shao D; Ni W; Tai G
    Oncotarget; 2015 Feb; 6(6):4253-65. PubMed ID: 25714018
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Salvianolic acid B exerts an anti-hepatocellular carcinoma effect by regulating the Hippo/YAP pathway and promoting pSmad3L to pSmad3C simultaneously.
    Xu W; Shi Z; Yu X; Xu Y; Chen Y; He Y; Gong Y; Huang C; Tan C; Yang Y
    Eur J Pharmacol; 2023 Jan; 939():175423. PubMed ID: 36509132
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.
    Matsuzaki K; Murata M; Yoshida K; Sekimoto G; Uemura Y; Sakaida N; Kaibori M; Kamiyama Y; Nishizawa M; Fujisawa J; Okazaki K; Seki T
    Hepatology; 2007 Jul; 46(1):48-57. PubMed ID: 17596875
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation.
    Zhou Y; Tong X; Ren S; Wang X; Chen J; Mu Y; Sun M; Chen G; Zhang H; Liu P
    J Ethnopharmacol; 2016 Aug; 190():83-90. PubMed ID: 27282665
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Compound Astragalus and Salvia miltiorrhiza extract suppresses hepatocellular carcinoma progression by inhibiting fibrosis and PAI-1 mRNA transcription.
    Rui W; Xie L; Liu X; He S; Wu C; Zhang X; Zhang L; Yang Y
    J Ethnopharmacol; 2014; 151(1):198-209. PubMed ID: 24247078
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling, and amelioration of oxidative stress and inflammation.
    Mahmoud AM; Mohammed HM; Khadrawy SM; Galaly SR
    Chem Biol Interact; 2017 Nov; 277():146-158. PubMed ID: 28935427
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smad3 and its phosphoisoforms are prognostic predictors of hepatocellular carcinoma after curative hepatectomy.
    Kim SH; Ahn S; Park CK
    Hepatobiliary Pancreat Dis Int; 2012 Feb; 11(1):51-9. PubMed ID: 22251470
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of microRNA-21/145 and Smad3 domain-specific phosphorylation in hepatocellular carcinoma.
    Wang JY; Fang M; Boye A; Wu C; Wu JJ; Ma Y; Hou S; Kan Y; Yang Y
    Oncotarget; 2017 Oct; 8(49):84958-84973. PubMed ID: 29156696
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.