179 related articles for article (PubMed ID: 34157389)
1. Design, synthesis and antiproliferative activity of novel 2,4-diamino-5-methyleneaminopyrimidine derivatives as potential anticancer agents.
Li Q; Chen L; Jian XE; Lv DX; You WW; Zhao PL
Bioorg Med Chem Lett; 2021 Sep; 47():128213. PubMed ID: 34157389
[TBL] [Abstract][Full Text] [Related]
2. New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.
Farghaly AM; AboulWafa OM; Baghdadi HH; Abd El Razik HA; Sedra SMY; Shamaa MM
Bioorg Chem; 2021 Oct; 115():105208. PubMed ID: 34365057
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and antiproliferative activity of novel 5-nitropyrimidine-2,4-diamine derivatives bearing alkyl acetate moiety.
Zhao PL; Li YH; Yang HK; Chen P; Zhang B; Sun Q; Li Q; You WW
Eur J Med Chem; 2016 Aug; 118():161-9. PubMed ID: 27128180
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents.
Ye T; Han Y; Wang R; Yan P; Chen S; Hou Y; Zhao Y
Bioorg Chem; 2020 Jun; 99():103796. PubMed ID: 32283346
[TBL] [Abstract][Full Text] [Related]
5. Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3-mediated apoptosis.
Maher M; Kassab AE; Zaher AF; Mahmoud Z
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):532-546. PubMed ID: 30688116
[TBL] [Abstract][Full Text] [Related]
6. Novel imidazolone derivatives as potential dual inhibitors of checkpoint kinases 1 and 2: Design, synthesis, cytotoxicity evaluation, and mechanistic insights.
Sheta YS; Sarg MT; Abdulrahman FG; Nossier ES; Husseiny EM
Bioorg Chem; 2024 Aug; 149():107471. PubMed ID: 38823311
[TBL] [Abstract][Full Text] [Related]
7. Design, Synthesis, biological Evaluation, and molecular docking studies of novel Pyrazolo[3,4-d]Pyrimidine derivative scaffolds as potent EGFR inhibitors and cell apoptosis inducers.
Sherbiny FF; Bayoumi AH; El-Morsy AM; Sobhy M; Hagras M
Bioorg Chem; 2021 Nov; 116():105325. PubMed ID: 34507234
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, anticancer evaluation, molecular docking and cell cycle analysis of 3-methyl-4,7-dihydropyrazolo[1,5-a]pyrimidine derivatives as potent histone lysine demethylases (KDM) inhibitors and apoptosis inducers.
Metwally NH; Mohamed MS; Ragb EA
Bioorg Chem; 2019 Jul; 88():102929. PubMed ID: 31015179
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
Diao PC; Li Q; Hu MJ; Ma YF; You WW; Hong KH; Zhao PL
Eur J Med Chem; 2017 Jul; 134():110-118. PubMed ID: 28410492
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of novel 1,2,3-triazole-pyrimidine hybrids as potential anticancer agents.
Ma LY; Pang LP; Wang B; Zhang M; Hu B; Xue DQ; Shao KP; Zhang BL; Liu Y; Zhang E; Liu HM
Eur J Med Chem; 2014 Oct; 86():368-80. PubMed ID: 25180925
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
[TBL] [Abstract][Full Text] [Related]
12. Anti-proliferative potential of triphenyl substituted pyrimidines against MDA-MB-231, HCT-116 and HT-29 cancer cell lines.
Ranjan Dwivedi A; Kumar V; Kaur H; Kumar N; Prakash Yadav R; Poduri R; Baranwal S; Kumar V
Bioorg Med Chem Lett; 2020 Oct; 30(20):127468. PubMed ID: 32768647
[TBL] [Abstract][Full Text] [Related]
13. 2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study.
AboulWafa OM; Daabees HMG; Badawi WA
Bioorg Chem; 2020 Jun; 99():103798. PubMed ID: 32247112
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and cytotoxic activity of novel 2H-imidazo[1,2-c]pyrazolo[3,4-e]pyrimidine derivatives.
Zheng YG; Pei X; Xia DX; Wang YB; Jiang P; An L; Huang TH; Xue YS
Bioorg Chem; 2021 Apr; 109():104711. PubMed ID: 33609916
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, anticancer activity and effects on cell cycle profile and apoptosis of novel thieno[2,3-d]pyrimidine and thieno[3,2-e] triazolo[4,3-c]pyrimidine derivatives.
Kandeel MM; Refaat HM; Kassab AE; Shahin IG; Abdelghany TM
Eur J Med Chem; 2015 Jan; 90():620-32. PubMed ID: 25499930
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis and biological evaluation of novel 3-alkylsulfanyl-4-amino-1,2,4-triazole derivatives.
Zhao PL; Chen P; Li Q; Hu MJ; Diao PC; Pan ES; You WW
Bioorg Med Chem Lett; 2016 Aug; 26(15):3679-83. PubMed ID: 27287368
[TBL] [Abstract][Full Text] [Related]
17. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
Abdelhaleem EF; Abdelhameid MK; Kassab AE; Kandeel MM
Eur J Med Chem; 2018 Jan; 143():1807-1825. PubMed ID: 29133058
[TBL] [Abstract][Full Text] [Related]
18. Design, Synthesis and Screening of 4,6-Diaryl Pyridine and Pyrimidine Derivatives as Potential Cytotoxic Molecules.
Abd Elhameid MK; Ryad N; Al-Shorbagy MY; Mohammed MR; Ismail MM; El Meligie S
Chem Pharm Bull (Tokyo); 2018 Oct; 66(10):939-952. PubMed ID: 30111667
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and biological evaluation of 2,4-diamino pyrimidine derivatives as potent FAK inhibitors with anti-cancer and anti-angiogenesis activities.
Wang S; Zhang RH; Zhang H; Wang YC; Yang D; Zhao YL; Yan GY; Xu GB; Guan HY; Zhou YH; Cui DB; Liu T; Li YJ; Liao SG; Zhou M
Eur J Med Chem; 2021 Oct; 222():113573. PubMed ID: 34091209
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and anticancer evaluation of novel andrographolide derivatives bearing an α,β-unsaturated ketone moiety.
Cai W; Li J; Chen C; Wu J; Li J; Xue X
Bioorg Chem; 2021 Jul; 112():104941. PubMed ID: 33940445
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
