BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 34162976)

  • 1. Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools.
    Kychygina A; Dall'Osto M; Allen JAM; Cadoret JC; Piras V; Pickett HA; Crabbe L
    Sci Rep; 2021 Jun; 11(1):13195. PubMed ID: 34162976
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome.
    Aguado J; Sola-Carvajal A; Cancila V; Revêchon G; Ong PF; Jones-Weinert CW; Wallén Arzt E; Lattanzi G; Dreesen O; Tripodo C; Rossiello F; Eriksson M; d'Adda di Fagagna F
    Nat Commun; 2019 Nov; 10(1):4990. PubMed ID: 31740672
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Towards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson-Gilford progeria (HGPS).
    Dreesen O
    Biochem Soc Trans; 2020 Jun; 48(3):981-991. PubMed ID: 32539085
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transient introduction of human telomerase mRNA improves hallmarks of progeria cells.
    Li Y; Zhou G; Bruno IG; Zhang N; Sho S; Tedone E; Lai TP; Cooke JP; Shay JW
    Aging Cell; 2019 Aug; 18(4):e12979. PubMed ID: 31152494
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
    Chojnowski A; Ong PF; Wong ES; Lim JS; Mutalif RA; Navasankari R; Dutta B; Yang H; Liow YY; Sze SK; Boudier T; Wright GD; Colman A; Burke B; Stewart CL; Dreesen O
    Elife; 2015 Aug; 4():. PubMed ID: 26312502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hutchinson-Gilford progeria syndrome through the lens of transcription.
    Prokocimer M; Barkan R; Gruenbaum Y
    Aging Cell; 2013 Aug; 12(4):533-43. PubMed ID: 23496208
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Progerin-Induced Replication Stress Facilitates Premature Senescence in Hutchinson-Gilford Progeria Syndrome.
    Wheaton K; Campuzano D; Ma W; Sheinis M; Ho B; Brown GW; Benchimol S
    Mol Cell Biol; 2017 Jul; 37(14):. PubMed ID: 28483909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts.
    Eisch V; Lu X; Gabriel D; Djabali K
    Oncotarget; 2016 Apr; 7(17):24700-18. PubMed ID: 27015553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence.
    Benson EK; Lee SW; Aaronson SA
    J Cell Sci; 2010 Aug; 123(Pt 15):2605-12. PubMed ID: 20605919
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes.
    Kreienkamp R; Croke M; Neumann MA; Bedia-Diaz G; Graziano S; Dusso A; Dorsett D; Carlberg C; Gonzalo S
    Oncotarget; 2016 May; 7(21):30018-31. PubMed ID: 27145372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Premature aging syndromes: From patients to mechanism.
    Foo MXR; Ong PF; Dreesen O
    J Dermatol Sci; 2019 Nov; 96(2):58-65. PubMed ID: 31727429
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment.
    Columbaro M; Capanni C; Mattioli E; Novelli G; Parnaik VK; Squarzoni S; Maraldi NM; Lattanzi G
    Cell Mol Life Sci; 2005 Nov; 62(22):2669-78. PubMed ID: 16261260
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impairment of nuclear F-actin formation and its relevance to cellular phenotypes in Hutchinson-Gilford progeria syndrome.
    Takahashi Y; Hiratsuka S; Machida N; Takahashi D; Matsushita J; Hozak P; Misteli T; Miyamoto K; Harata M
    Nucleus; 2020 Dec; 11(1):250-263. PubMed ID: 32954953
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Progerin and telomere dysfunction collaborate to trigger cellular senescence in normal human fibroblasts.
    Cao K; Blair CD; Faddah DA; Kieckhaefer JE; Olive M; Erdos MR; Nabel EG; Collins FS
    J Clin Invest; 2011 Jul; 121(7):2833-44. PubMed ID: 21670498
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress.
    Paradisi M; McClintock D; Boguslavsky RL; Pedicelli C; Worman HJ; Djabali K
    BMC Cell Biol; 2005 Jun; 6():27. PubMed ID: 15982412
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Are There Common Mechanisms Between the Hutchinson-Gilford Progeria Syndrome and Natural Aging?
    Ashapkin VV; Kutueva LI; Kurchashova SY; Kireev II
    Front Genet; 2019; 10():455. PubMed ID: 31156709
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis.
    Bridger JM; Kill IR
    Exp Gerontol; 2004 May; 39(5):717-24. PubMed ID: 15130666
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations.
    Gonzalo S; Kreienkamp R; Askjaer P
    Ageing Res Rev; 2017 Jan; 33():18-29. PubMed ID: 27374873
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
    Finley J
    Med Hypotheses; 2018 Sep; 118():151-162. PubMed ID: 30037605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.
    McClintock D; Gordon LB; Djabali K
    Proc Natl Acad Sci U S A; 2006 Feb; 103(7):2154-9. PubMed ID: 16461887
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.