These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 34163821)

  • 1. Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy.
    Marques MA; Landim-Vieira M; Moraes AH; Sun B; Johnston JR; Dieseldorff Jones KM; Cino EA; Parvatiyar MS; Valera IC; Silva JL; Galkin VE; Chase PB; Kekenes-Huskey PM; de Oliveira GAP; Pinto JR
    Chem Sci; 2021 Apr; 12(21):7308-7323. PubMed ID: 34163821
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and functional impact of troponin C-mediated Ca
    Gonzalez-Martinez D; Johnston JR; Landim-Vieira M; Ma W; Antipova O; Awan O; Irving TC; Bryant Chase P; Pinto JR
    J Mol Cell Cardiol; 2018 Oct; 123():26-37. PubMed ID: 30138628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of Mg
    Rayani K; Hantz ER; Haji-Ghassemi O; Li AY; Spuches AM; Van Petegem F; Solaro RJ; Lindert S; Tibbits GF
    FEBS J; 2022 Dec; 289(23):7446-7465. PubMed ID: 35838319
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Changes in the dynamics of the cardiac troponin C molecule explain the effects of Ca
    Stevens CM; Rayani K; Singh G; Lotfalisalmasi B; Tieleman DP; Tibbits GF
    J Biol Chem; 2017 Jul; 292(28):11915-11926. PubMed ID: 28533433
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In Vivo Analysis of Troponin C Knock-In (A8V) Mice: Evidence that TNNC1 Is a Hypertrophic Cardiomyopathy Susceptibility Gene.
    Martins AS; Parvatiyar MS; Feng HZ; Bos JM; Gonzalez-Martinez D; Vukmirovic M; Turna RS; Sanchez-Gonzalez MA; Badger CD; Zorio DAR; Singh RK; Wang Y; Jin JP; Ackerman MJ; Pinto JR
    Circ Cardiovasc Genet; 2015 Oct; 8(5):653-664. PubMed ID: 26304555
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mutation in TNNC1-encoded cardiac troponin C, TNNC1-A31S, predisposes to hypertrophic cardiomyopathy and ventricular fibrillation.
    Parvatiyar MS; Landstrom AP; Figueiredo-Freitas C; Potter JD; Ackerman MJ; Pinto JR
    J Biol Chem; 2012 Sep; 287(38):31845-55. PubMed ID: 22815480
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.
    Pinto JR; Parvatiyar MS; Jones MA; Liang J; Ackerman MJ; Potter JD
    J Biol Chem; 2009 Jul; 284(28):19090-100. PubMed ID: 19439414
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypertrophic Cardiomyopathy Cardiac Troponin C Mutations Differentially Affect Slow Skeletal and Cardiac Muscle Regulation.
    Veltri T; Landim-Vieira M; Parvatiyar MS; Gonzalez-Martinez D; Dieseldorff Jones KM; Michell CA; Dweck D; Landstrom AP; Chase PB; Pinto JR
    Front Physiol; 2017; 8():221. PubMed ID: 28473771
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular Effects of cTnC DCM Mutations on Calcium Sensitivity and Myofilament Activation-An Integrated Multiscale Modeling Study.
    Dewan S; McCabe KJ; Regnier M; McCulloch AD; Lindert S
    J Phys Chem B; 2016 Aug; 120(33):8264-75. PubMed ID: 27133568
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TnI Structural Interface with the N-Terminal Lobe of TnC as a Determinant of Cardiac Contractility.
    Vetter AD; Houang EM; Sell JJ; Thompson BR; Sham YY; Metzger JM
    Biophys J; 2018 Apr; 114(7):1646-1656. PubMed ID: 29642034
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of calcium binding and the hypertrophic cardiomyopathy A8V mutation on the dynamic equilibrium between closed and open conformations of the regulatory N-domain of isolated cardiac troponin C.
    Cordina NM; Liew CK; Gell DA; Fajer PG; Mackay JP; Brown LJ
    Biochemistry; 2013 Mar; 52(11):1950-62. PubMed ID: 23425245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional characterization of TNNC1 rare variants identified in dilated cardiomyopathy.
    Pinto JR; Siegfried JD; Parvatiyar MS; Li D; Norton N; Jones MA; Liang J; Potter JD; Hershberger RE
    J Biol Chem; 2011 Sep; 286(39):34404-12. PubMed ID: 21832052
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C.
    Landstrom AP; Parvatiyar MS; Pinto JR; Marquardt ML; Bos JM; Tester DJ; Ommen SR; Potter JD; Ackerman MJ
    J Mol Cell Cardiol; 2008 Aug; 45(2):281-8. PubMed ID: 18572189
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypertrophic cardiomyopathy mutation in cardiac troponin T (R95H) attenuates length-dependent activation in guinea pig cardiac muscle fibers.
    Mickelson AV; Chandra M
    Am J Physiol Heart Circ Physiol; 2017 Dec; 313(6):H1180-H1189. PubMed ID: 28842439
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation.
    Johnston JR; Landim-Vieira M; Marques MA; de Oliveira GAP; Gonzalez-Martinez D; Moraes AH; He H; Iqbal A; Wilnai Y; Birk E; Zucker N; Silva JL; Chase PB; Pinto JR
    J Biol Chem; 2019 Dec; 294(52):20054-20069. PubMed ID: 31748410
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the L29Q Hypertrophic Cardiomyopathy Mutation in Cardiac Troponin C by Paramagnetic Relaxation Enhancement Nuclear Magnetic Resonance.
    Potluri PR; Cordina NM; Kachooei E; Brown LJ
    Biochemistry; 2019 Feb; 58(7):908-917. PubMed ID: 30620548
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Familial hypertrophic cardiomyopathy related cardiac troponin C L29Q mutation alters length-dependent activation and functional effects of phosphomimetic troponin I*.
    Li AY; Stevens CM; Liang B; Rayani K; Little S; Davis J; Tibbits GF
    PLoS One; 2013; 8(11):e79363. PubMed ID: 24260207
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structural and functional effects of the familial hypertrophic cardiomyopathy-linked cardiac troponin C mutation, L29Q.
    Robertson IM; Sevrieva I; Li MX; Irving M; Sun YB; Sykes BD
    J Mol Cell Cardiol; 2015 Oct; 87():257-69. PubMed ID: 26341255
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation.
    Abdullah S; Lynn ML; McConnell MT; Klass MM; Baldo AP; Schwartz SD; Tardiff JC
    J Biol Chem; 2019 Oct; 294(40):14634-14647. PubMed ID: 31387947
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of protein kinase C dependent phosphorylation and a familial hypertrophic cardiomyopathy-related mutation of cardiac troponin I on structural transition of troponin C and myofilament activation.
    Kobayashi T; Dong WJ; Burkart EM; Cheung HC; Solaro RJ
    Biochemistry; 2004 May; 43(20):5996-6004. PubMed ID: 15147183
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.