288 related articles for article (PubMed ID: 34164627)
1. A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage.
Zou X; Koh GCC; Nanda AS; Degasperi A; Urgo K; Roumeliotis TI; Agu CA; Badja C; Momen S; Young J; Amarante TD; Side L; Brice G; Perez-Alonso V; Rueda D; Gomez C; Bushell W; Harris R; Choudhary JS; ; Jiricny J; Skarnes WC; Nik-Zainal S
Nat Cancer; 2021 Jun; 2(6):643-657. PubMed ID: 34164627
[TBL] [Abstract][Full Text] [Related]
2. Mutational signatures of DNA mismatch repair deficiency in
Meier B; Volkova NV; Hong Y; Schofield P; Campbell PJ; Gerstung M; Gartner A
Genome Res; 2018 May; 28(5):666-675. PubMed ID: 29636374
[TBL] [Abstract][Full Text] [Related]
3. A Compendium of Mutational Signatures of Environmental Agents.
Kucab JE; Zou X; Morganella S; Joel M; Nanda AS; Nagy E; Gomez C; Degasperi A; Harris R; Jackson SP; Arlt VM; Phillips DH; Nik-Zainal S
Cell; 2019 May; 177(4):821-836.e16. PubMed ID: 30982602
[TBL] [Abstract][Full Text] [Related]
4. Two main mutational processes operate in the absence of DNA mismatch repair.
Németh E; Lovrics A; Gervai JZ; Seki M; Rospo G; Bardelli A; Szüts D
DNA Repair (Amst); 2020 May; 89():102827. PubMed ID: 32126497
[TBL] [Abstract][Full Text] [Related]
5. Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.
Drost J; van Boxtel R; Blokzijl F; Mizutani T; Sasaki N; Sasselli V; de Ligt J; Behjati S; Grolleman JE; van Wezel T; Nik-Zainal S; Kuiper RP; Cuppen E; Clevers H
Science; 2017 Oct; 358(6360):234-238. PubMed ID: 28912133
[TBL] [Abstract][Full Text] [Related]
6. Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations.
Poulos RC; Wong YT; Ryan R; Pang H; Wong JWH
PLoS Genet; 2018 Nov; 14(11):e1007779. PubMed ID: 30412573
[TBL] [Abstract][Full Text] [Related]
7. Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases.
Sun J; Wang C; Zhang Y; Xu L; Fang W; Zhu Y; Zheng Y; Chen X; Xie X; Hu X; Hu W; Zheng J; Li P; Yu J; Mei Z; Cai X; Wang B; Hu Z; Shu Y; Shen H; Gu Y
Nat Commun; 2019 Jul; 10(1):3190. PubMed ID: 31320627
[TBL] [Abstract][Full Text] [Related]
8. Analysis of mutational signatures in C. elegans: Implications for cancer genome analysis.
Meier B; Volkova NV; Gerstung M; Gartner A
DNA Repair (Amst); 2020 Nov; 95():102957. PubMed ID: 32980770
[TBL] [Abstract][Full Text] [Related]
9. Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels.
Stadler ZK; Battaglin F; Middha S; Hechtman JF; Tran C; Cercek A; Yaeger R; Segal NH; Varghese AM; Reidy-Lagunes DL; Kemeny NE; Salo-Mullen EE; Ashraf A; Weiser MR; Garcia-Aguilar J; Robson ME; Offit K; Arcila ME; Berger MF; Shia J; Solit DB; Saltz LB
J Clin Oncol; 2016 Jun; 34(18):2141-7. PubMed ID: 27022117
[TBL] [Abstract][Full Text] [Related]
10. Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function.
Lai FP; Lau ST; Wong JK; Gui H; Wang RX; Zhou T; Lai WH; Tse HF; Tam PK; Garcia-Barcelo MM; Ngan ES
Gastroenterology; 2017 Jul; 153(1):139-153.e8. PubMed ID: 28342760
[TBL] [Abstract][Full Text] [Related]
11. Oxidative stress and the DNA mismatch repair pathway.
Brierley DJ; Martin SA
Antioxid Redox Signal; 2013 Jun; 18(18):2420-8. PubMed ID: 23121537
[TBL] [Abstract][Full Text] [Related]
12. Microsatellite Instability and Mismatch Repair Deficiency Define a Distinct Subset of Lung Cancers Characterized by Smoking Exposure, High Tumor Mutational Burden, and Recurrent Somatic MLH1 Inactivation.
Yang SR; Gedvilaite E; Ptashkin R; Chang J; Ziegler J; Mata DA; Villafania LB; Nafa K; Hechtman JF; Benayed R; Zehir A; Benhamida J; Arcila ME; Mandelker D; Rudin CM; Paik PK; Drilon A; Schoenfeld AJ; Ladanyi M
J Thorac Oncol; 2024 Mar; 19(3):409-424. PubMed ID: 37838086
[TBL] [Abstract][Full Text] [Related]
13. Lynch syndrome and Lynch syndrome mimics: The growing complex landscape of hereditary colon cancer.
Carethers JM; Stoffel EM
World J Gastroenterol; 2015 Aug; 21(31):9253-61. PubMed ID: 26309352
[TBL] [Abstract][Full Text] [Related]
14. Mutational spectra and mutational signatures: Insights into cancer aetiology and mechanisms of DNA damage and repair.
Phillips DH
DNA Repair (Amst); 2018 Nov; 71():6-11. PubMed ID: 30236628
[TBL] [Abstract][Full Text] [Related]
15. Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential.
Giner-Calabuig M; De Leon S; Wang J; Fehlmann TD; Ukaegbu C; Gibson J; Alustiza-Fernandez M; Pico MD; Alenda C; Herraiz M; Carrillo-Palau M; Salces I; Reyes J; Ortega SP; Obrador-Hevia A; Cecchini M; Syngal S; Stoffel E; Ellis NA; Sweasy J; Jover R; Llor X; Xicola RM
Br J Cancer; 2022 Jun; 126(11):1595-1603. PubMed ID: 35197584
[TBL] [Abstract][Full Text] [Related]
16. Functional interrogation of Lynch syndrome-associated MSH2 missense variants via CRISPR-Cas9 gene editing in human embryonic stem cells.
Rath A; Mishra A; Ferreira VD; Hu C; Omerza G; Kelly K; Hesse A; Reddi HV; Grady JP; Heinen CD
Hum Mutat; 2019 Nov; 40(11):2044-2056. PubMed ID: 31237724
[TBL] [Abstract][Full Text] [Related]
17. Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome.
Golubicki M; Bonjoch L; Acuña-Ochoa JG; Díaz-Gay M; Muñoz J; Cuatrecasas M; Ocaña T; Iseas S; Mendez G; Cisterna D; Schubert SA; Nielsen M; van Wezel T; Goldberg Y; Pikarsky E; Robbio J; Roca E; Castells A; Balaguer F; Antelo M; Castellví-Bel S
JCI Insight; 2020 Sep; 5(18):. PubMed ID: 32841224
[TBL] [Abstract][Full Text] [Related]
18. Successful correction of factor V deficiency of patient-derived iPSCs by CRISPR/Cas9-mediated gene editing.
Nakamura T; Morishige S; Ozawa H; Kuboyama K; Yamasaki Y; Oya S; Yamaguchi M; Aoyama K; Seki R; Mouri F; Osaki K; Okamura T; Mizuno S; Nagafuji K
Haemophilia; 2020 Sep; 26(5):826-833. PubMed ID: 32700411
[TBL] [Abstract][Full Text] [Related]
19. Mutational signatures reveal ternary relationships between homologous recombination repair, APOBEC, and mismatch repair in gynecological cancers.
Farmanbar A; Firouzi S; Kneller R; Khiabanian H
J Transl Med; 2022 Feb; 20(1):65. PubMed ID: 35109853
[TBL] [Abstract][Full Text] [Related]
20. Homozygous germ-line mutation of the PMS2 mismatch repair gene: a unique case report of constitutional mismatch repair deficiency (CMMRD).
Ramchander NC; Ryan NA; Crosbie EJ; Evans DG
BMC Med Genet; 2017 Apr; 18(1):40. PubMed ID: 28381238
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
