BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 34165921)

  • 1. Sustained compensatory p38 MAPK signaling following treatment with MAPK inhibitors induces the immunosuppressive protein CD73 in cancer: combined targeting could improve outcomes.
    Terp MG; Gammelgaard OL; Vever H; Gjerstorff MF; Ditzel HJ
    Mol Oncol; 2021 Dec; 15(12):3299-3316. PubMed ID: 34165921
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.
    Kocher D; Cao L; Guiho R; Langhammer M; Lai YL; Becker P; Hamdi H; Friedel D; Selt F; Vonhören D; Zaman J; Valinciute G; Herter S; Picard D; Rettenmeier J; Maass KK; Pajtler KW; Remke M; von Deimling A; Pusch S; Pfister SM; Oehme I; Jones DTW; Halbach S; Brummer T; Martinez-Barbera JP; Witt O; Milde T; Sigaud R
    J Neurooncol; 2024 Jun; 168(2):317-332. PubMed ID: 38630384
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.
    Vashisht Gopal YN; Gammon S; Prasad R; Knighton B; Pisaneschi F; Roszik J; Feng N; Johnson S; Pramanik S; Sudderth J; Sui D; Hudgens C; Fischer GM; Deng W; Reuben A; Peng W; Wang J; McQuade JL; Tetzlaff MT; Di Francesco ME; Marszalek J; Piwnica-Worms D; DeBerardinis RJ; Davies MA
    Clin Cancer Res; 2019 Nov; 25(21):6429-6442. PubMed ID: 31439581
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of
    Aloia A; Müllhaupt D; Chabbert CD; Eberhart T; Flückiger-Mangual S; Vukolic A; Eichhoff O; Irmisch A; Alexander LT; Scibona E; Frederick DT; Miao B; Tian T; Cheng C; Kwong LN; Wei Z; Sullivan RJ; Boland GM; Herlyn M; Flaherty KT; Zamboni N; Dummer R; Zhang G; Levesque MP; Krek W; Kovacs WJ
    Clin Cancer Res; 2019 Nov; 25(22):6852-6867. PubMed ID: 31375515
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Notch signaling activation induces cell death in MAPKi-resistant melanoma cells.
    Mikheil DM; Prabhakar K; Arshad A; Rodriguez CI; Newton MA; Setaluri V
    Pigment Cell Melanoma Res; 2019 Jul; 32(4):528-539. PubMed ID: 30614626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance.
    Yang Z; Wang Y; Liu S; Deng W; Lomeli SH; Moriceau G; Wohlschlegel J; Piva M; Lo RS
    Cancer Discov; 2022 Aug; 12(8):1942-1959. PubMed ID: 35638972
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combined tazemetostat and MAPKi enhances differentiation of papillary thyroid cancer cells harbouring BRAF
    Fu H; Cheng L; Sa R; Jin Y; Chen L
    J Cell Mol Med; 2020 Mar; 24(6):3336-3345. PubMed ID: 31970877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in
    Usta D; Sigaud R; Buhl JL; Selt F; Marquardt V; Pauck D; Jansen J; Pusch S; Ecker J; Hielscher T; Vollmer J; Sommerkamp AC; Rubner T; Hargrave D; van Tilburg CM; Pfister SM; Jones DTW; Remke M; Brummer T; Witt O; Milde T
    Mol Cancer Ther; 2020 Aug; 19(8):1736-1750. PubMed ID: 32451331
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRAF inhibitors and their immunological effects in malignant melanoma.
    Adams R; Coumbe JEM; Coumbe BGT; Thomas J; Willsmore Z; Dimitrievska M; Yasuzawa-Parker M; Hoyle M; Ingar S; Geh JLC; MacKenzie Ross AD; Healy C; Papa S; Lacy KE; Karagiannis SN
    Expert Rev Clin Immunol; 2022 Apr; 18(4):347-362. PubMed ID: 35195495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas.
    Sigaud R; Albert TK; Hess C; Hielscher T; Winkler N; Kocher D; Walter C; Münter D; Selt F; Usta D; Ecker J; Brentrup A; Hasselblatt M; Thomas C; Varghese J; Capper D; Thomale UW; Hernáiz Driever P; Simon M; Horn S; Herz NA; Koch A; Sahm F; Hamelmann S; Faria-Andrade A; Jabado N; Schuhmann MU; Schouten-van Meeteren AYN; Hoving E; Brummer T; van Tilburg CM; Pfister SM; Witt O; Jones DTW; Kerl K; Milde T
    Nat Commun; 2023 Jul; 14(1):4533. PubMed ID: 37500667
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.
    Wang B; Krall EB; Aguirre AJ; Kim M; Widlund HR; Doshi MB; Sicinska E; Sulahian R; Goodale A; Cowley GS; Piccioni F; Doench JG; Root DE; Hahn WC
    Cell Rep; 2017 Feb; 18(6):1543-1557. PubMed ID: 28178529
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors.
    Sander CA; Rush EA; Shi J; Arantes LMRB; Tesi RJ; Ross MA; Calderon MJ; Watkins SC; Kirkwood JM; Ferris RL; Butterfield LH; Vujanovic L
    J Transl Med; 2022 Jul; 20(1):331. PubMed ID: 35879777
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP; Yang YX; Liu QL; Pan ST; He ZX; Zhang X; Yang T; Chen XW; Wang D; Qiu JX; Zhou SF
    Drug Des Devel Ther; 2015; 9():1627-52. PubMed ID: 25834401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Recurrent Tumor Cell-Intrinsic and -Extrinsic Alterations during MAPKi-Induced Melanoma Regression and Early Adaptation.
    Song C; Piva M; Sun L; Hong A; Moriceau G; Kong X; Zhang H; Lomeli S; Qian J; Yu CC; Damoiseaux R; Kelley MC; Dahlman KB; Scumpia PO; Sosman JA; Johnson DB; Ribas A; Hugo W; Lo RS
    Cancer Discov; 2017 Nov; 7(11):1248-1265. PubMed ID: 28864476
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alantolactone enhances the sensitivity of melanoma to MAPK pathway inhibitors by targeting inhibition of STAT3 activation and down-regulating stem cell markers.
    Zhao K; Zhao Q; Dai X; Wen X; Luo X; Duan Y; Yang Z; Dai Q
    Cancer Cell Int; 2024 May; 24(1):191. PubMed ID: 38822350
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oncogenic Ras modulates p38 MAPK-mediated inflammatory cytokine production in glioblastoma cells.
    Munoz L; Yeung YT; Grewal T
    Cancer Biol Ther; 2016 Apr; 17(4):355-63. PubMed ID: 26794430
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid.
    Matesic DF; Sidorova TS; Burns TJ; Bell AM; Tran PL; Ruch RJ; May SW
    J Cell Biochem; 2012 Jan; 113(1):269-81. PubMed ID: 21898549
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma.
    Ferretti LP; Böhi F; Leslie Pedrioli DM; Cheng PF; Ferrari E; Baumgaertner P; Alvarado-Diaz A; Sella F; Cereghetti A; Turko P; Wright RH; De Bock K; Speiser DE; Ferrari R; Levesque MP; Hottiger MO
    Cancer Res; 2023 Dec; 83(23):3974-3988. PubMed ID: 37729428
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.
    Park MA; Zhang G; Mitchell C; Rahmani M; Hamed H; Hagan MP; Yacoub A; Curiel DT; Fisher PB; Grant S; Dent P
    Mol Cancer Ther; 2008 Sep; 7(9):2633-48. PubMed ID: 18790746
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitogen-activated protein kinase-activated protein kinase-2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer.
    Morgan D; Berggren KL; Spiess CD; Smith HM; Tejwani A; Weir SJ; Lominska CE; Thomas SM; Gan GN
    Mol Carcinog; 2022 Feb; 61(2):173-199. PubMed ID: 34559922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.