BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 34168658)

  • 1. PRMT5 Promotes Cyclin E1 and Cell Cycle Progression in CD4 Th1 Cells and Correlates With EAE Severity.
    Amici SA; Osman W; Guerau-de-Arellano M
    Front Immunol; 2021; 12():695947. PubMed ID: 34168658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
    Webb LM; Amici SA; Jablonski KA; Savardekar H; Panfil AR; Li L; Zhou W; Peine K; Karkhanis V; Bachelder EM; Ainslie KM; Green PL; Li C; Baiocchi RA; Guerau-de-Arellano M
    J Immunol; 2017 Feb; 198(4):1439-1451. PubMed ID: 28087667
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NF-κB/mTOR/MYC Axis Drives PRMT5 Protein Induction After T Cell Activation via Transcriptional and Non-transcriptional Mechanisms.
    Webb LM; Narvaez Miranda J; Amici SA; Sengupta S; Nagy G; Guerau-de-Arellano M
    Front Immunol; 2019; 10():524. PubMed ID: 30941147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade.
    Wei TY; Juan CC; Hisa JY; Su LJ; Lee YC; Chou HY; Chen JM; Wu YC; Chiu SC; Hsu CP; Liu KL; Yu CT
    Cancer Sci; 2012 Sep; 103(9):1640-50. PubMed ID: 22726390
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The magnitude of the antigen-specific T cell response is separated from the severity of spinal cord histopathology in remitting-relapsing experimental autoimmune encephalomyelitis.
    Batoulis H; Uhl M; Addicks K; Lehmann PV; Kuerten S
    Glia; 2012 May; 60(5):794-805. PubMed ID: 22319015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prmt5 deficiency inhibits CD4+ T-cell Klf2/S1pr1 expression and ameliorates EAE disease.
    Zheng Y; Chen Z; Zhou B; Chen S; Chen N; Shen L
    J Neuroinflammation; 2023 Aug; 20(1):183. PubMed ID: 37533053
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cutting edge: mast cells regulate disease severity in a relapsing-remitting model of multiple sclerosis.
    Sayed BA; Walker ME; Brown MA
    J Immunol; 2011 Mar; 186(6):3294-8. PubMed ID: 21325623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PRMT5 competitively binds to CDK4 to promote G1-S transition upon glucose induction in hepatocellular carcinoma.
    Yang H; Zhao X; Zhao L; Liu L; Li J; Jia W; Liu J; Huang G
    Oncotarget; 2016 Nov; 7(44):72131-72147. PubMed ID: 27708221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.
    Webb LM; Sengupta S; Edell C; Piedra-Quintero ZL; Amici SA; Miranda JN; Bevins M; Kennemer A; Laliotis G; Tsichlis PN; Guerau-de-Arellano M
    J Clin Invest; 2020 Apr; 130(4):1683-1698. PubMed ID: 32091410
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma.
    Jiang H; Zhu Y; Zhou Z; Xu J; Jin S; Xu K; Zhang H; Sun Q; Wang J; Xu J
    Cancer Med; 2018 Mar; 7(3):869-882. PubMed ID: 29441724
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulatory effect of celastrol on Th1/Th2 cytokines profile, TLR2 and CD3+ T-lymphocyte expression in a relapsing-remitting model of multiple sclerosis in rats.
    Abdin AA; Hasby EA
    Eur J Pharmacol; 2014 Nov; 742():102-12. PubMed ID: 25218987
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-IL-16 therapy reduces CD4+ T-cell infiltration and improves paralysis and histopathology of relapsing EAE.
    Skundric DS; Dai R; Zakarian VL; Bessert D; Skoff RP; Cruikshank WW; Kurjakovic Z
    J Neurosci Res; 2005 Mar; 79(5):680-93. PubMed ID: 15682385
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.
    Chung J; Karkhanis V; Tae S; Yan F; Smith P; Ayers LW; Agostinelli C; Pileri S; Denis GV; Baiocchi RA; Sif S
    J Biol Chem; 2013 Dec; 288(49):35534-47. PubMed ID: 24189068
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The circular RNA circZFR phosphorylates Rb promoting cervical cancer progression by regulating the SSBP1/CDK2/cyclin E1 complex.
    Zhou M; Yang Z; Wang D; Chen P; Zhang Y
    J Exp Clin Cancer Res; 2021 Jan; 40(1):48. PubMed ID: 33516252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. COX-2 inhibitors modulate IL-12 signaling through JAK-STAT pathway leading to Th1 response in experimental allergic encephalomyelitis.
    Muthian G; Raikwar HP; Johnson C; Rajasingh J; Kalgutkar A; Marnett LJ; Bright JJ
    J Clin Immunol; 2006 Jan; 26(1):73-85. PubMed ID: 16418805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing-remitting multiple sclerosis.
    Kleist C; Mohr E; Gaikwad S; Dittmar L; Kuerten S; Platten M; Mier W; Schmitt M; Opelz G; Terness P
    J Transl Med; 2016 May; 14(1):99. PubMed ID: 27131971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Helicobacter pylori releases a factor(s) inhibiting cell cycle progression of human gastric cell lines by affecting cyclin E/cdk2 kinase activity and Rb protein phosphorylation through enhanced p27(KIP1) protein expression.
    Sommi P; Savio M; Stivala LA; Scotti C; Mignosi P; Prosperi E; Vannini V; Solcia E
    Exp Cell Res; 2002 Nov; 281(1):128-39. PubMed ID: 12441136
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis.
    Kleiter I; Song J; Lukas D; Hasan M; Neumann B; Croxford AL; Pedré X; Hövelmeyer N; Yogev N; Mildner A; Prinz M; Wiese E; Reifenberg K; Bittner S; Wiendl H; Steinman L; Becker C; Bogdahn U; Neurath MF; Steinbrecher A; Waisman A
    Brain; 2010 Apr; 133(Pt 4):1067-81. PubMed ID: 20354004
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis.
    Berard JL; Zarruk JG; Arbour N; Prat A; Yong VW; Jacques FH; Akira S; David S
    Glia; 2012 Jul; 60(7):1145-59. PubMed ID: 22499213
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination.
    Rostami A; Ciric B
    J Neurol Sci; 2013 Oct; 333(1-2):76-87. PubMed ID: 23578791
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.