These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia. Ma J; Zhao S; Qiao X; Knight T; Edwards H; Polin L; Kushner J; Dzinic SH; White K; Wang G; Zhao L; Lin H; Wang Y; Taub JW; Ge Y Clin Cancer Res; 2019 Nov; 25(22):6815-6826. PubMed ID: 31320594 [TBL] [Abstract][Full Text] [Related]
3. Midostaurin/PKC412 for the treatment of newly diagnosed FLT3 mutation-positive acute myeloid leukemia. Luskin MR; DeAngelo DJ Expert Rev Hematol; 2017 Dec; 10(12):1033-1045. PubMed ID: 29069942 [TBL] [Abstract][Full Text] [Related]
4. Effects of the multi-kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia. Weisberg E; Meng C; Case AE; Tiv HL; Gokhale PC; Buhrlage SJ; Yang J; Liu X; Wang J; Gray N; Adamia S; Sattler M; Stone R; Griffin JD J Cell Mol Med; 2020 Mar; 24(5):2968-2980. PubMed ID: 31967735 [TBL] [Abstract][Full Text] [Related]
5. Combining the novel FLT3 and MERTK dual inhibitor MRX-2843 with venetoclax results in promising antileukemic activity against FLT3-ITD AML. Wu S; Liu F; Gai Y; Carter J; Edwards H; Hüttemann M; Wang G; Li C; Taub JW; Wang Y; Ge Y Leuk Res; 2024 Sep; 144():107547. PubMed ID: 38968731 [TBL] [Abstract][Full Text] [Related]
6. Midostaurin for the treatment of adult patients with newly diagnosed acute myeloid leukemia that is FLT3 mutation-positive. Garcia JS; Percival ME Drugs Today (Barc); 2017 Oct; 53(10):531-543. PubMed ID: 29286055 [TBL] [Abstract][Full Text] [Related]
7. MDM2- and FLT3-inhibitors in the treatment of Seipel K; Marques MAT; Sidler C; Mueller BU; Pabst T Haematologica; 2018 Nov; 103(11):1862-1872. PubMed ID: 29976747 [TBL] [Abstract][Full Text] [Related]
8. Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells. Stölzel F; Steudel C; Oelschlägel U; Mohr B; Koch S; Ehninger G; Thiede C Ann Hematol; 2010 Jul; 89(7):653-62. PubMed ID: 20119833 [TBL] [Abstract][Full Text] [Related]
9. Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia. Brinton LT; Zhang P; Williams K; Canfield D; Orwick S; Sher S; Wasmuth R; Beaver L; Cempre C; Skinner J; Cannon M; Govande M; Harrington B; Lehman A; Byrd JC; Lapalombella R; Blachly JS J Hematol Oncol; 2020 Oct; 13(1):139. PubMed ID: 33076970 [TBL] [Abstract][Full Text] [Related]
10. FLT3 inhibitors in the treatment of acute myeloid leukemia: current status and future perspectives. Mosquera Orgueira A; Bao Pérez L; Mosquera Torre A; Peleteiro Raíndo A; Cid López M; Díaz Arias JÁ; Ferreiro Ferro R; Antelo Rodríguez B; González Pérez MS; Albors Ferreiro M; Alonso Vence N; Pérez Encinas MM; Bello López JL; Martinelli G; Cerchione C Minerva Med; 2020 Oct; 111(5):427-442. PubMed ID: 32955823 [TBL] [Abstract][Full Text] [Related]
11. FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. Pratz KW; Sato T; Murphy KM; Stine A; Rajkhowa T; Levis M Blood; 2010 Feb; 115(7):1425-32. PubMed ID: 20007803 [TBL] [Abstract][Full Text] [Related]
12. Midostaurin in Combination With Standard Chemotherapy for Treatment of Newly Diagnosed FMS-Like Tyrosine Kinase 3 (FLT3) Mutation-Positive Acute Myeloid Leukemia. Kim M; Williams S Ann Pharmacother; 2018 Apr; 52(4):364-369. PubMed ID: 29231051 [TBL] [Abstract][Full Text] [Related]
13. Combination of midostaurin and ATRA exerts dose-dependent dual effects on acute myeloid leukemia cells with wild type FLT3. Lu H; Weng XQ; Sheng Y; Wu J; Xi HM; Cai X BMC Cancer; 2022 Jul; 22(1):749. PubMed ID: 35810308 [TBL] [Abstract][Full Text] [Related]
14. Midostaurin: A New Oral Agent Targeting FMS-Like Tyrosine Kinase 3-Mutant Acute Myeloid Leukemia. Stansfield LC; Pollyea DA Pharmacotherapy; 2017 Dec; 37(12):1586-1599. PubMed ID: 28976600 [TBL] [Abstract][Full Text] [Related]
15. Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation. Stone RM; Mandrekar SJ; Sanford BL; Laumann K; Geyer S; Bloomfield CD; Thiede C; Prior TW; Döhner K; Marcucci G; Lo-Coco F; Klisovic RB; Wei A; Sierra J; Sanz MA; Brandwein JM; de Witte T; Niederwieser D; Appelbaum FR; Medeiros BC; Tallman MS; Krauter J; Schlenk RF; Ganser A; Serve H; Ehninger G; Amadori S; Larson RA; Döhner H N Engl J Med; 2017 Aug; 377(5):454-464. PubMed ID: 28644114 [TBL] [Abstract][Full Text] [Related]
16. FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation. Zhu R; Li L; Nguyen B; Seo J; Wu M; Seale T; Levis M; Duffield A; Hu Y; Small D Signal Transduct Target Ther; 2021 May; 6(1):186. PubMed ID: 34024909 [TBL] [Abstract][Full Text] [Related]
19. MZH29 is a novel potent inhibitor that overcomes drug resistance FLT3 mutations in acute myeloid leukemia. Xu B; Zhao Y; Wang X; Gong P; Ge W Leukemia; 2017 Apr; 31(4):913-921. PubMed ID: 27773927 [TBL] [Abstract][Full Text] [Related]
20. Synergy of FLT3 inhibitors and the small molecule inhibitor of LIM kinase1/2 CEL_Amide in FLT3-ITD mutated Acute Myeloblastic Leukemia (AML) cells. Djamai H; Berrou J; Dupont M; Kaci A; Ehlert JE; Weber H; Baruchel A; Paublant F; Prudent R; Gardin C; Dombret H; Braun T Leuk Res; 2021 Jan; 100():106490. PubMed ID: 33373830 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]