These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 34181717)

  • 1. Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay.
    Park SH; Bennett-Baker P; Ahmed S; Arlt MF; Ljungman M; Glover TW; Wilson TE
    Nucleic Acids Res; 2021 Jul; 49(13):7507-7524. PubMed ID: 34181717
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Replication stress induces tumor-like microdeletions in FHIT/FRA3B.
    Durkin SG; Ragland RL; Arlt MF; Mulle JG; Warren ST; Glover TW
    Proc Natl Acad Sci U S A; 2008 Jan; 105(1):246-51. PubMed ID: 18162546
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Large transcription units unify copy number variants and common fragile sites arising under replication stress.
    Wilson TE; Arlt MF; Park SH; Rajendran S; Paulsen M; Ljungman M; Glover TW
    Genome Res; 2015 Feb; 25(2):189-200. PubMed ID: 25373142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Initiation of genome instability and preneoplastic processes through loss of Fhit expression.
    Saldivar JC; Miuma S; Bene J; Hosseini SA; Shibata H; Sun J; Wheeler LJ; Mathews CK; Huebner K
    PLoS Genet; 2012; 8(11):e1003077. PubMed ID: 23209436
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms shaping the mutational landscape of the FRA3B/FHIT-deficient cancer genome.
    Saldivar JC; Park D
    Genes Chromosomes Cancer; 2019 May; 58(5):317-323. PubMed ID: 30242938
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired replication dynamics at the FRA3B common fragile site.
    Palakodeti A; Lucas I; Jiang Y; Young DJ; Fernald AA; Karrison T; Le Beau MM
    Hum Mol Genet; 2010 Jan; 19(1):99-110. PubMed ID: 19815620
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Common chromosome fragile sites in human and murine epithelial cells and FHIT/FRA3B loss-induced global genome instability.
    Hosseini SA; Horton S; Saldivar JC; Miuma S; Stampfer MR; Heerema NA; Huebner K
    Genes Chromosomes Cancer; 2013 Nov; 52(11):1017-29. PubMed ID: 23929738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired Replication Timing Promotes Tissue-Specific Expression of Common Fragile Sites.
    Maccaroni K; Balzano E; Mirimao F; Giunta S; Pelliccia F
    Genes (Basel); 2020 Mar; 11(3):. PubMed ID: 32204553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genetic instability of the tumor suppressor gene FHIT in normal human cells.
    Palumbo E; Tosoni E; Matricardi L; Russo A
    Genes Chromosomes Cancer; 2013 Sep; 52(9):832-44. PubMed ID: 23780737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers.
    Turner BC; Ottey M; Zimonjic DB; Potoczek M; Hauck WW; Pequignot E; Keck-Waggoner CL; Sevignani C; Aldaz CM; McCue PA; Palazzo J; Huebner K; Popescu NC
    Cancer Res; 2002 Jul; 62(14):4054-60. PubMed ID: 12124341
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of the common fragile site FRA3B does not affect FHIT expression.
    Michael D; Rajewsky MF
    Oncogene; 2001 Mar; 20(14):1798-801. PubMed ID: 11313927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes.
    Helmrich A; Ballarino M; Tora L
    Mol Cell; 2011 Dec; 44(6):966-77. PubMed ID: 22195969
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Common fragile sites, extremely large genes, neural development and cancer.
    Smith DI; Zhu Y; McAvoy S; Kuhn R
    Cancer Lett; 2006 Jan; 232(1):48-57. PubMed ID: 16221525
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fragile Genes That Are Frequently Altered in Cancer: Players Not Passengers.
    Karras JR; Schrock MS; Batar B; Huebner K
    Cytogenet Genome Res; 2016; 150(3-4):208-216. PubMed ID: 28199992
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 3D genome organization contributes to genome instability at fragile sites.
    Sarni D; Sasaki T; Irony Tur-Sinai M; Miron K; Rivera-Mulia JC; Magnuson B; Ljungman M; Gilbert DM; Kerem B
    Nat Commun; 2020 Jul; 11(1):3613. PubMed ID: 32680994
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment.
    Wan C; Kulkarni A; Wang YH
    Mutat Res; 2010 Apr; 686(1-2):39-46. PubMed ID: 20060399
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel approach to simultaneously scan genes at fragile sites.
    Willem P; Brown J; Schouten J
    BMC Cancer; 2006 Aug; 6():205. PubMed ID: 16895604
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fhit deficiency-induced global genome instability promotes mutation and clonal expansion.
    Miuma S; Saldivar JC; Karras JR; Waters CE; Paisie CA; Wang Y; Jin V; Sun J; Druck T; Zhang J; Huebner K
    PLoS One; 2013; 8(11):e80730. PubMed ID: 24244712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The epicenter of chromosomal fragility of Fra14A2, the mouse ortholog of human FRA3B common fragile site, is largely attached to the nuclear matrix in lymphocytes but not in other cell types that do not express such a fragility.
    Guadarrama-Ponce R; Aranda-Anzaldo A
    J Cell Biochem; 2020 Mar; 121(3):2209-2224. PubMed ID: 31646677
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Genome: does a paucity of initiation events lead to fragility?].
    Letessier A; Birnbaum D; Debatisse M; Chaffanet M
    Med Sci (Paris); 2011; 27(8-9):707-9. PubMed ID: 21880257
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 12.