158 related articles for article (PubMed ID: 34182359)
1. Design and synthesis of Mannich base-type derivatives containing imidazole and benzimidazole as lead compounds for drug discovery in Chagas Disease.
Beltran-Hortelano I; Atherton RL; Rubio-Hernández M; Sanz-Serrano J; Alcolea V; Kelly JM; Pérez-Silanes S; Olmo F
Eur J Med Chem; 2021 Nov; 223():113646. PubMed ID: 34182359
[TBL] [Abstract][Full Text] [Related]
2. In Vitro and in Vivo Anti-Trypanosoma cruzi Activity of New Arylamine Mannich Base-Type Derivatives.
Moreno-Viguri E; Jiménez-Montes C; Martín-Escolano R; Santivañez-Veliz M; Martin-Montes A; Azqueta A; Jimenez-Lopez M; Zamora Ledesma S; Cirauqui N; López de Ceráin A; Marín C; Sánchez-Moreno M; Pérez-Silanes S
J Med Chem; 2016 Dec; 59(24):10929-10945. PubMed ID: 28002965
[TBL] [Abstract][Full Text] [Related]
3. Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation.
Paucar R; Martín-Escolano R; Moreno-Viguri E; Azqueta A; Cirauqui N; Marín C; Sánchez-Moreno M; Pérez-Silanes S
Bioorg Med Chem; 2019 Sep; 27(17):3902-3917. PubMed ID: 31345745
[TBL] [Abstract][Full Text] [Related]
4. Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi.
Martín-Escolano R; Moreno-Viguri E; Santivañez-Veliz M; Martin-Montes A; Medina-Carmona E; Paucar R; Marín C; Azqueta A; Cirauqui N; Pey AL; Pérez-Silanes S; Sánchez-Moreno M
J Med Chem; 2018 Jul; 61(13):5643-5663. PubMed ID: 29883536
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease.
Monteiro ME; Lechuga G; Lara LS; Souto BA; Viganó MG; Bourguignon SC; Calvet CM; Oliveira FOR; Alves CR; Souza-Silva F; Santos MS; Pereira MCS
Eur J Med Chem; 2019 Nov; 182():111610. PubMed ID: 31434040
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and molecular docking studies of novel N-arylsulfonyl-benzimidazoles with anti Trypanosoma cruzi activity.
Miana GE; Ribone SR; Vera DMA; Sánchez-Moreno M; Mazzieri MR; Quevedo MA
Eur J Med Chem; 2019 Mar; 165():1-10. PubMed ID: 30641409
[TBL] [Abstract][Full Text] [Related]
7. A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives.
Paucar R; Martín-Escolano R; Moreno-Viguri E; Cirauqui N; Rodrigues CR; Marín C; Sánchez-Moreno M; Pérez-Silanes S; Ravera M; Gabano E
Eur J Med Chem; 2019 Feb; 163():569-582. PubMed ID: 30554132
[TBL] [Abstract][Full Text] [Related]
8. A quinoxaline derivative as a potent chemotherapeutic agent, alone or in combination with benznidazole, against Trypanosoma cruzi.
Rodrigues JH; Ueda-Nakamura T; Corrêa AG; Sangi DP; Nakamura CV
PLoS One; 2014; 9(1):e85706. PubMed ID: 24465654
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and Biological in vitro and in vivo Evaluation of 2-(5-Nitroindazol-1-yl)ethylamines and Related Compounds as Potential Therapeutic Alternatives for Chagas Disease.
Martín-Escolano R; Aguilera-Venegas B; Marín C; Martín-Montes Á; Martín-Escolano J; Medina-Carmona E; Arán VJ; Sánchez-Moreno M
ChemMedChem; 2018 Oct; 13(19):2104-2118. PubMed ID: 30098232
[TBL] [Abstract][Full Text] [Related]
10. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi.
de Oliveira Filho GB; Cardoso MVO; Espíndola JWP; Oliveira E Silva DA; Ferreira RS; Coelho PL; Anjos PSD; Santos ES; Meira CS; Moreira DRM; Soares MBP; Leite ACL
Eur J Med Chem; 2017 Dec; 141():346-361. PubMed ID: 29031078
[TBL] [Abstract][Full Text] [Related]
11. Investigating the structure-activity relationships of N'-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against Trypanosoma cruzi to design novel active compounds.
Palace-Berl F; Pasqualoto KFM; Zingales B; Moraes CB; Bury M; Franco CH; da Silva Neto AL; Murayama JS; Nunes SL; Silva MN; Tavares LC
Eur J Med Chem; 2018 Jan; 144():29-40. PubMed ID: 29247858
[TBL] [Abstract][Full Text] [Related]
12. Discovery of Strong 3-Nitro-2-Phenyl-
Carey SM; O'Neill DM; Conner GB; Sherman J; Rodriguez A; D'Antonio EL
Int J Mol Sci; 2024 Apr; 25(8):. PubMed ID: 38673904
[TBL] [Abstract][Full Text] [Related]
13. Experimental models in Chagas disease: a review of the methodologies applied for screening compounds against Trypanosoma cruzi.
Fonseca-Berzal C; Arán VJ; Escario JA; Gómez-Barrio A
Parasitol Res; 2018 Nov; 117(11):3367-3380. PubMed ID: 30232605
[TBL] [Abstract][Full Text] [Related]
14. Synthesis of novel quinine analogs and evaluation of their effects on Trypanosoma cruzi.
Ceole LF; Gandhi H; Villamizar LH; Soares MJ; O'Sullivan TP
Future Med Chem; 2018 Feb; 10(4):391-408. PubMed ID: 29380636
[TBL] [Abstract][Full Text] [Related]
15. Imidazoles from nitroallylic acetates and α-bromonitroalkenes with amidines: synthesis and trypanocidal activity studies.
Gopi E; Kumar T; Menna-Barreto RF; Valença WO; da Silva Júnior EN; Namboothiri IN
Org Biomol Chem; 2015 Oct; 13(38):9862-71. PubMed ID: 26288376
[TBL] [Abstract][Full Text] [Related]
16. Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening.
Melo-Filho CC; Braga RC; Muratov EN; Franco CH; Moraes CB; Freitas-Junior LH; Andrade CH
Eur J Med Chem; 2019 Feb; 163():649-659. PubMed ID: 30562700
[TBL] [Abstract][Full Text] [Related]
17. Trypanocidal effect of the benzyl ester of N-propyl oxamate: a bi-potential prodrug for the treatment of experimental Chagas disease.
Wong-Baeza C; Nogueda-Torres B; Serna M; Meza-Toledo S; Baeza I; Wong C
BMC Pharmacol Toxicol; 2015 Apr; 16():10. PubMed ID: 25896924
[TBL] [Abstract][Full Text] [Related]
18. Novel 2-arylazoimidazole derivatives as inhibitors of Trypanosoma cruzi proliferation: Synthesis and evaluation of their biological activity.
Salerno A; Celentano AM; López J; Lara V; Gaozza C; Balcazar DE; Carrillo C; Frank FM; Blanco MM
Eur J Med Chem; 2017 Jan; 125():327-334. PubMed ID: 27688187
[TBL] [Abstract][Full Text] [Related]
19. Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death.
da Silva EB; Oliveira E Silva DA; Oliveira AR; da Silva Mendes CH; Dos Santos TA; da Silva AC; de Castro MC; Ferreira RS; Moreira DR; Cardoso MV; de Simone CA; Pereira VR; Leite AC
Eur J Med Chem; 2017 Apr; 130():39-50. PubMed ID: 28242550
[TBL] [Abstract][Full Text] [Related]
20. New Imidazole-Based Compounds Active Against Trypanosoma cruzi.
Adeyemi OS; Molina MT; Eseola AO; Fonseca-Berzal C; Gómez-Barrio A
Comb Chem High Throughput Screen; 2017; 20(1):20-24. PubMed ID: 28071587
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
