These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 34183381)

  • 1. 3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice.
    Hoshi M; Kubo H; Ando T; Tashita C; Nakamoto K; Yamamoto Y; Tezuka H; Saito K
    Immunohorizons; 2021 Jun; 5(6):523-534. PubMed ID: 34183381
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback.
    Wilson K; Auer M; Binnie M; Zheng X; Pham NT; Iredale JP; Webster SP; Mole DJ
    Cell Death Dis; 2016 Apr; 7(4):e2197. PubMed ID: 27077813
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain.
    Giorgini F; Huang SY; Sathyasaikumar KV; Notarangelo FM; Thomas MA; Tararina M; Wu HQ; Schwarcz R; Muchowski PJ
    J Biol Chem; 2013 Dec; 288(51):36554-66. PubMed ID: 24189070
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Absence of kynurenine 3-monooxygenase reduces mortality of acute viral myocarditis in mice.
    Kubo H; Hoshi M; Mouri A; Tashita C; Yamamoto Y; Nabeshima T; Saito K
    Immunol Lett; 2017 Jan; 181():94-100. PubMed ID: 27889626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kynurenine 3-monooxygenase (KMO), and signal transducer and activator of transcription 3 (STAT3) expression is involved in tumour proliferation and predicts poor survival in canine melanoma.
    Liu IL; Chung TF; Huang WH; Hsu CH; Liu CC; Chiu YH; Huang KC; Liao AT; Lin CS
    Vet Comp Oncol; 2021 Mar; 19(1):79-91. PubMed ID: 32720434
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kynurenine 3-monooxygenase is a critical regulator of renal ischemia-reperfusion injury.
    Zheng X; Zhang A; Binnie M; McGuire K; Webster SP; Hughes J; Howie SEM; Mole DJ
    Exp Mol Med; 2019 Feb; 51(2):1-14. PubMed ID: 30760699
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of LC/MS/MS, high-throughput enzymatic and cellular assays for the characterization of compounds that inhibit kynurenine monooxygenase (KMO).
    Winkler D; Beconi M; Toledo-Sherman LM; Prime M; Ebneth A; Dominguez C; Muñoz-Sanjuan I
    J Biomol Screen; 2013 Sep; 18(8):879-89. PubMed ID: 23690293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model.
    Rojewska E; Piotrowska A; Makuch W; Przewlocka B; Mika J
    Neuropharmacology; 2016 Mar; 102():80-91. PubMed ID: 26524415
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kynurenine 3-monooxygenase is implicated in antidepressants-responsive depressive-like behaviors and monoaminergic dysfunctions.
    Tashiro T; Murakami Y; Mouri A; Imamura Y; Nabeshima T; Yamamoto Y; Saito K
    Behav Brain Res; 2017 Jan; 317():279-285. PubMed ID: 27693848
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Maternal genotype determines kynurenic acid levels in the fetal brain: Implications for the pathophysiology of schizophrenia.
    Beggiato S; Notarangelo FM; Sathyasaikumar KV; Giorgini F; Schwarcz R
    J Psychopharmacol; 2018 Nov; 32(11):1223-1232. PubMed ID: 30354938
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kynurenine Monooxygenase Expression and Activity in Human Astrocytomas.
    Vázquez Cervantes GI; Pineda B; Ramírez Ortega D; Salazar A; González Esquivel DF; Rembao D; Zavala Vega S; Gómez-Manzo S; Pérez de la Cruz G; Pérez de la Cruz V
    Cells; 2021 Aug; 10(8):. PubMed ID: 34440798
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Importance of kynurenine 3-monooxygenase for spontaneous firing and pharmacological responses of midbrain dopamine neurons: Relevance for schizophrenia.
    Tufvesson-Alm M; Schwieler L; Schwarcz R; Goiny M; Erhardt S; Engberg G
    Neuropharmacology; 2018 Aug; 138():130-139. PubMed ID: 29879409
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma?
    Connor TJ; Starr N; O'Sullivan JB; Harkin A
    Neurosci Lett; 2008 Aug; 441(1):29-34. PubMed ID: 18584961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. N-(6-phenylpyridazin-3-yl)benzenesulfonamides as highly potent, brain-permeable, and orally active kynurenine monooxygenase inhibitors.
    Kimura H; Suda H; Kassai M; Endo M; Deai Y; Yahata M; Miyajima M; Isobe Y
    Bioorg Med Chem Lett; 2021 Feb; 33():127753. PubMed ID: 33359168
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.
    Laumet G; Zhou W; Dantzer R; Edralin JD; Huo X; Budac DP; O'Connor JC; Lee AW; Heijnen CJ; Kavelaars A
    Brain Behav Immun; 2017 Nov; 66():94-102. PubMed ID: 28709913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase.
    Kim HT; Na BK; Chung J; Kim S; Kwon SK; Cha H; Son J; Cho JM; Hwang KY
    Cell Chem Biol; 2018 Apr; 25(4):426-438.e4. PubMed ID: 29429898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neurotoxic kynurenine metabolism is increased in the dorsal hippocampus and drives distinct depressive behaviors during inflammation.
    Parrott JM; Redus L; Santana-Coelho D; Morales J; Gao X; O'Connor JC
    Transl Psychiatry; 2016 Oct; 6(10):e918. PubMed ID: 27754481
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of autophagy with 3-methyladenine is protective in a lethal model of murine endotoxemia and polymicrobial sepsis.
    Li Q; Li L; Fei X; Zhang Y; Qi C; Hua S; Gong F; Fang M
    Innate Immun; 2018 May; 24(4):231-239. PubMed ID: 29673286
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.
    Greenhill CJ; Gould J; Ernst M; Jarnicki A; Hertzog PJ; Mansell A; Jenkins BJ
    Immunol Cell Biol; 2012 May; 90(5):559-63. PubMed ID: 21670738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis of kynurenine 3-monooxygenase inhibition.
    Amaral M; Levy C; Heyes DJ; Lafite P; Outeiro TF; Giorgini F; Leys D; Scrutton NS
    Nature; 2013 Apr; 496(7445):382-5. PubMed ID: 23575632
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.