BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 34183647)

  • 1. U2AF1 mutation promotes tumorigenicity through facilitating autophagy flux mediated by FOXO3a activation in myelodysplastic syndromes.
    Zhu Y; Song D; Guo J; Jin J; Tao Y; Zhang Z; Xu F; He Q; Li X; Chang C; Wu L
    Cell Death Dis; 2021 Jun; 12(7):655. PubMed ID: 34183647
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ribosome biogenesis is a downstream effector of the oncogenic U2AF1-S34F mutation.
    Akef A; McGraw K; Cappell SD; Larson DR
    PLoS Biol; 2020 Nov; 18(11):e3000920. PubMed ID: 33137094
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Effect of U2AF1 Mutation to Inflammatory Cytokine Expression in SKM-1 Cells through FOXO3a-Bim Signaling Pathway].
    Zhu YQ; Wu LY
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2021 Dec; 29(6):1858-1863. PubMed ID: 34893123
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Foxo3a-dependent Bim transcription protects mice from a high fat diet via inhibition of activation of the NLRP3 inflammasome by facilitating autophagy flux in Kupffer cells.
    Liu Y; Zhang W; Wu X; Gong J
    Oncotarget; 2017 May; 8(21):34258-34267. PubMed ID: 28427239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
    Shirai CL; White BS; Tripathi M; Tapia R; Ley JN; Ndonwi M; Kim S; Shao J; Carver A; Saez B; Fulton RS; Fronick C; O'Laughlin M; Lagisetti C; Webb TR; Graubert TA; Walter MJ
    Nat Commun; 2017 Jan; 8():14060. PubMed ID: 28067246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prognostic value of U2AF1 mutant in patients with de novo myelodysplastic syndromes: a meta-analysis.
    Wang H; Zhang N; Wu X; Zheng X; Ling Y; Gong Y
    Ann Hematol; 2019 Dec; 98(12):2629-2639. PubMed ID: 31754743
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene
    Fei DL; Zhen T; Durham B; Ferrarone J; Zhang T; Garrett L; Yoshimi A; Abdel-Wahab O; Bradley RK; Liu P; Varmus H
    Proc Natl Acad Sci U S A; 2018 Oct; 115(44):E10437-E10446. PubMed ID: 30322915
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice.
    Kim SP; Srivatsan SN; Chavez M; Shirai CL; White BS; Ahmed T; Alberti MO; Shao J; Nunley R; White LS; Bednarski J; Pehrson JR; Walter MJ
    Cell Rep; 2021 Aug; 36(9):109626. PubMed ID: 34469727
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis.
    Gurule NJ; Malcolm KC; Harris C; Knapp JR; O'Connor BP; McClendon J; Janssen WJ; Lee FFY; Price C; Osaghae-Nosa J; Wheeler EA; McMahon CM; Pietras EM; Pollyea DA; Alper S
    Leukemia; 2023 Oct; 37(10):2115-2124. PubMed ID: 37591942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3' End Formation.
    Park SM; Ou J; Chamberlain L; Simone TM; Yang H; Virbasius CM; Ali AM; Zhu LJ; Mukherjee S; Raza A; Green MR
    Mol Cell; 2016 May; 62(4):479-90. PubMed ID: 27184077
    [TBL] [Abstract][Full Text] [Related]  

  • 11. U2AF1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity.
    Badar T; Vanegas YAM; Nanaa A; Foran JM; Al-Kali A; Mangaonkar A; Murthy H; Alkhateeb HB; Viswanatha D; He R; Shah M; Yi CA; Litzow MR; Gangat N; Tefferi A; Patnaik MM
    Blood Cancer J; 2023 Sep; 13(1):149. PubMed ID: 37735430
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential U2AF1 mutation sites, burden and co-mutation genes can predict prognosis in patients with myelodysplastic syndrome.
    Wang H; Guo Y; Dong Z; Li T; Xie X; Wan D; Jiang Z; Yu J; Guo R
    Sci Rep; 2020 Oct; 10(1):18622. PubMed ID: 33122737
    [TBL] [Abstract][Full Text] [Related]  

  • 13. U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing.
    Okeyo-Owuor T; White BS; Chatrikhi R; Mohan DR; Kim S; Griffith M; Ding L; Ketkar-Kulkarni S; Hundal J; Laird KM; Kielkopf CL; Ley TJ; Walter MJ; Graubert TA
    Leukemia; 2015 Apr; 29(4):909-17. PubMed ID: 25311244
    [TBL] [Abstract][Full Text] [Related]  

  • 14. U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.
    Smith MA; Choudhary GS; Pellagatti A; Choi K; Bolanos LC; Bhagat TD; Gordon-Mitchell S; Von Ahrens D; Pradhan K; Steeples V; Kim S; Steidl U; Walter M; Fraser IDC; Kulkarni A; Salomonis N; Komurov K; Boultwood J; Verma A; Starczynowski DT
    Nat Cell Biol; 2019 May; 21(5):640-650. PubMed ID: 31011167
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
    Biancon G; Joshi P; Zimmer JT; Hunck T; Gao Y; Lessard MD; Courchaine E; Barentine AES; Machyna M; Botti V; Qin A; Gbyli R; Patel A; Song Y; Kiefer L; Viero G; Neuenkirchen N; Lin H; Bewersdorf J; Simon MD; Neugebauer KM; Tebaldi T; Halene S
    Mol Cell; 2022 Mar; 82(6):1107-1122.e7. PubMed ID: 35303483
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation.
    Warnasooriya C; Feeney CF; Laird KM; Ermolenko DN; Kielkopf CL
    Nucleic Acids Res; 2020 Jun; 48(10):5695-5709. PubMed ID: 32343311
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Decitabine-Induced Changes in Human Myelodysplastic Syndrome Cell Line SKM-1 Are Mediated by FOXO3A Activation.
    Zeng W; Dai H; Yan M; Cai X; Luo H; Ke M; Liu Z
    J Immunol Res; 2017; 2017():4302320. PubMed ID: 29124072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of Akt/FoxO3a/Skp2 Axis Is Critically Involved in Berberine-Induced Cell Cycle Arrest in Hepatocellular Carcinoma Cells.
    Li F; Dong X; Lin P; Jiang J
    Int J Mol Sci; 2018 Jan; 19(2):. PubMed ID: 29360760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prognostic significance of
    Li B; Zou D; Yang S; Ouyang G; Mu Q
    J Int Med Res; 2020 Mar; 48(3):300060519891013. PubMed ID: 31826693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo.
    Shirai CL; Ley JN; White BS; Kim S; Tibbitts J; Shao J; Ndonwi M; Wadugu B; Duncavage EJ; Okeyo-Owuor T; Liu T; Griffith M; McGrath S; Magrini V; Fulton RS; Fronick C; O'Laughlin M; Graubert TA; Walter MJ
    Cancer Cell; 2015 May; 27(5):631-43. PubMed ID: 25965570
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.