BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

299 related articles for article (PubMed ID: 34186021)

  • 1. BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation.
    Conway E; Rossi F; Fernandez-Perez D; Ponzo E; Ferrari KJ; Zanotti M; Manganaro D; Rodighiero S; Tamburri S; Pasini D
    Mol Cell; 2021 Sep; 81(17):3526-3541.e8. PubMed ID: 34186021
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression.
    Tamburri S; Lavarone E; Fernández-Pérez D; Conway E; Zanotti M; Manganaro D; Pasini D
    Mol Cell; 2020 Feb; 77(4):840-856.e5. PubMed ID: 31883952
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PR-DUB safeguards Polycomb repression through H2AK119ub1 restriction.
    Li R; Huang D; Zhao Y; Yuan Y; Sun X; Dai Z; Huo D; Liu X; Helin K; Li MJ; Wu X
    Cell Prolif; 2023 Oct; 56(10):e13457. PubMed ID: 36959757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PR-DUB maintains the expression of critical genes through FOXK1/2- and ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination.
    Kolovos P; Nishimura K; Sankar A; Sidoli S; Cloos PA; Helin K; Christensen J
    Genome Res; 2020 Aug; 30(8):1119-1130. PubMed ID: 32747411
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome.
    Fursova NA; Turberfield AH; Blackledge NP; Findlater EL; Lastuvkova A; Huseyin MK; Dobrinić P; Klose RJ
    Genes Dev; 2021 May; 35(9-10):749-770. PubMed ID: 33888563
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PR-DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub1, an antagonist of chromatin compaction.
    Bonnet J; Boichenko I; Kalb R; Le Jeune M; Maltseva S; Pieropan M; Finkl K; Fierz B; Müller J
    Genes Dev; 2022 Oct; 36(19-20):1046-1061. PubMed ID: 36357125
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.
    Ge W; Yu C; Li J; Yu Z; Li X; Zhang Y; Liu CP; Li Y; Tian C; Zhang X; Li G; Zhu B; Xu RM
    Nature; 2023 Apr; 616(7955):176-182. PubMed ID: 36991118
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer.
    Tamburri S; Conway E; Pasini D
    Trends Genet; 2022 Apr; 38(4):333-352. PubMed ID: 34426021
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genomic context- and H2AK119 ubiquitination-dependent inheritance of human Polycomb silencing.
    Shafiq TA; Yu J; Feng W; Zhang Y; Zhou H; Paulo JA; Gygi SP; Moazed D
    Sci Adv; 2024 May; 10(19):eadl4529. PubMed ID: 38718120
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of BAP1 function leads to EZH2-dependent transformation.
    LaFave LM; Béguelin W; Koche R; Teater M; Spitzer B; Chramiec A; Papalexi E; Keller MD; Hricik T; Konstantinoff K; Micol JB; Durham B; Knutson SK; Campbell JE; Blum G; Shi X; Doud EH; Krivtsov AV; Chung YR; Khodos I; de Stanchina E; Ouerfelli O; Adusumilli PS; Thomas PM; Kelleher NL; Luo M; Keilhack H; Abdel-Wahab O; Melnick A; Armstrong SA; Levine RL
    Nat Med; 2015 Nov; 21(11):1344-9. PubMed ID: 26437366
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polycomb-mediated histone modifications and gene regulation.
    Ito S; Umehara T; Koseki H
    Biochem Soc Trans; 2024 Feb; 52(1):151-161. PubMed ID: 38288743
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PRC1 Catalytic Activity Is Central to Polycomb System Function.
    Blackledge NP; Fursova NA; Kelley JR; Huseyin MK; Feldmann A; Klose RJ
    Mol Cell; 2020 Feb; 77(4):857-874.e9. PubMed ID: 31883950
    [TBL] [Abstract][Full Text] [Related]  

  • 13. H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction.
    Zhao J; Lan J; Wang M; Liu C; Fang Z; Song A; Zhang T; Wang L; Zhu B; Chen P; Yu J; Li G
    Mol Cell; 2024 Apr; 84(7):1191-1205.e7. PubMed ID: 38458202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing.
    Moussa HF; Bsteh D; Yelagandula R; Pribitzer C; Stecher K; Bartalska K; Michetti L; Wang J; Zepeda-Martinez JA; Elling U; Stuckey JI; James LI; Frye SV; Bell O
    Nat Commun; 2019 Apr; 10(1):1931. PubMed ID: 31036804
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RYBP stimulates PRC1 to shape chromatin-based communication between Polycomb repressive complexes.
    Rose NR; King HW; Blackledge NP; Fursova NA; Ember KJ; Fischer R; Kessler BM; Klose RJ
    Elife; 2016 Oct; 5():. PubMed ID: 27705745
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Goldilocks meets Polycomb.
    Verrijzer CP
    Genes Dev; 2022 Oct; 36(19-20):1043-1045. PubMed ID: 36460465
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation.
    Almeida M; Pintacuda G; Masui O; Koseki Y; Gdula M; Cerase A; Brown D; Mould A; Innocent C; Nakayama M; Schermelleh L; Nesterova TB; Koseki H; Brockdorff N
    Science; 2017 Jun; 356(6342):1081-1084. PubMed ID: 28596365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Polycomb group RING finger proteins 3/5 activate transcription via an interaction with the pluripotency factor Tex10 in embryonic stem cells.
    Zhao W; Huang Y; Zhang J; Liu M; Ji H; Wang C; Cao N; Li C; Xia Y; Jiang Q; Qin J
    J Biol Chem; 2017 Dec; 292(52):21527-21537. PubMed ID: 29054931
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.
    Blackledge NP; Farcas AM; Kondo T; King HW; McGouran JF; Hanssen LLP; Ito S; Cooper S; Kondo K; Koseki Y; Ishikura T; Long HK; Sheahan TW; Brockdorff N; Kessler BM; Koseki H; Klose RJ
    Cell; 2014 Jun; 157(6):1445-1459. PubMed ID: 24856970
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polycomb complexes redundantly maintain epidermal stem cell identity during development.
    Cohen I; Bar C; Liu H; Valdes VJ; Zhao D; Galbo PM; Silva JM; Koseki H; Zheng D; Ezhkova E
    Genes Dev; 2021 Mar; 35(5-6):354-366. PubMed ID: 33602871
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.