BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 34186047)

  • 1. The HSP90 inhibitor, XL888, enhanced cell apoptosis via downregulating STAT3 after insufficient radiofrequency ablation in hepatocellular carcinoma.
    Sun C; Bai M; Ke W; Wang X; Zhao X; Lu Z
    Life Sci; 2021 Oct; 282():119762. PubMed ID: 34186047
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms.
    Paraiso KH; Haarberg HE; Wood E; Rebecca VW; Chen YA; Xiang Y; Ribas A; Lo RS; Weber JS; Sondak VK; John JK; Sarnaik AA; Koomen JM; Smalley KS
    Clin Cancer Res; 2012 May; 18(9):2502-14. PubMed ID: 22351686
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Incomplete radiofrequency ablation induced chemoresistance by up-regulating heat shock protein 70 in hepatocellular carcinoma.
    Wang F; Xu C; Li G; Lv P; Gu J
    Exp Cell Res; 2021 Dec; 409(2):112910. PubMed ID: 34801560
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stress-induced phosphoprotein 1 mediates hepatocellular carcinoma metastasis after insufficient radiofrequency ablation.
    Su T; Liao J; Dai Z; Xu L; Chen S; Wang Y; Peng Z; Zhang Q; Peng S; Kuang M
    Oncogene; 2018 Jun; 37(26):3514-3527. PubMed ID: 29559743
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90.
    Bussenius J; Blazey CM; Aay N; Anand NK; Arcalas A; Baik T; Bowles OJ; Buhr CA; Costanzo S; Curtis JK; DeFina SC; Dubenko L; Heuer TS; Huang P; Jaeger C; Joshi A; Kennedy AR; Kim AI; Lara K; Lee J; Li J; Lougheed JC; Ma S; Malek S; Manalo JC; Martini JF; McGrath G; Nicoll M; Nuss JM; Pack M; Peto CJ; Tsang TH; Wang L; Womble SW; Yakes M; Zhang W; Rice KD
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5396-404. PubMed ID: 22877636
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insufficient radiofrequency ablation promotes the metastasis of residual hepatocellular carcinoma cells via upregulating flotillin proteins.
    Zhang N; Li H; Qin C; Ma D; Zhao Y; Zhu W; Wang L
    J Cancer Res Clin Oncol; 2019 Apr; 145(4):895-907. PubMed ID: 30820716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of Wee1, AKT, and CDK4 underlies the efficacy of the HSP90 inhibitor XL888 in an in vivo model of NRAS-mutant melanoma.
    Haarberg HE; Paraiso KH; Wood E; Rebecca VW; Sondak VK; Koomen JM; Smalley KS
    Mol Cancer Ther; 2013 Jun; 12(6):901-12. PubMed ID: 23538902
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Hsp90 inhibitor SNX-2112 induces apoptosis of human hepatocellular carcinoma cells: the role of ER stress.
    Wang X; Wang S; Liu Y; Ding W; Zheng K; Xiang Y; Liu K; Wang D; Zeng Y; Xia M; Yang D; Wang Y
    Biochem Biophys Res Commun; 2014 Mar; 446(1):160-6. PubMed ID: 24582562
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting autophagy enhances heat stress-induced apoptosis via the ATP-AMPK-mTOR axis for hepatocellular carcinoma.
    Jiang J; Chen S; Li K; Zhang C; Tan Y; Deng Q; Chai Y; Wang X; Chen G; Feng K; Zhang L; Xie CM; Ma K
    Int J Hyperthermia; 2019; 36(1):499-510. PubMed ID: 31007109
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
    Xu Q; Tu J; Dou C; Zhang J; Yang L; Liu X; Lei K; Liu Z; Wang Y; Li L; Bao H; Wang J; Tu K
    Mol Cancer; 2017 Dec; 16(1):178. PubMed ID: 29262861
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer.
    Zhang Y; Ware MB; Zaidi MY; Ruggieri AN; Olson BM; Komar H; Farren MR; Nagaraju GP; Zhang C; Chen Z; Sarmiento JM; Ahmed R; Maithel SK; El-Rayes BF; Lesinski GB
    Mol Cancer Ther; 2021 Jan; 20(1):150-160. PubMed ID: 33037138
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation.
    Lai SC; Su YT; Chi CC; Kuo YC; Lee KF; Wu YC; Lan PC; Yang MH; Chang TS; Huang YH
    J Exp Clin Cancer Res; 2019 Nov; 38(1):474. PubMed ID: 31771617
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined inhibition of AURKA and HSF1 suppresses proliferation and promotes apoptosis in hepatocellular carcinoma by activating endoplasmic reticulum stress.
    Shen Z; Yin L; Zhou H; Ji X; Jiang C; Zhu X; He X
    Cell Oncol (Dordr); 2021 Oct; 44(5):1035-1049. PubMed ID: 34176092
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
    Leng AM; Liu T; Yang J; Cui JF; Li XH; Zhu YN; Xiong T; Zhang G; Chen Y
    Cell Biol Int; 2012 Oct; 36(10):893-9. PubMed ID: 22694478
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Silencing of signal transducer and activator of transcription 3 expression by RNA interference suppresses growth of human hepatocellular carcinoma in tumor-bearing nude mice.
    Li J; Piao YF; Jiang Z; Chen L; Sun HB
    World J Gastroenterol; 2009 Jun; 15(21):2602-8. PubMed ID: 19496189
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo.
    Mohan CD; Bharathkumar H; Bulusu KC; Pandey V; Rangappa S; Fuchs JE; Shanmugam MK; Dai X; Li F; Deivasigamani A; Hui KM; Kumar AP; Lobie PE; Bender A; Basappa ; Sethi G; Rangappa KS
    J Biol Chem; 2014 Dec; 289(49):34296-307. PubMed ID: 25320076
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TLX3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma.
    Wang C; Dou C; Wang Y; Liu Z; Roberts L; Zheng X
    Int J Biol Sci; 2019; 15(8):1696-1711. PubMed ID: 31360112
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insufficient radiofrequency ablation-induced autophagy contributes to the rapid progression of residual hepatocellular carcinoma through the HIF-1α/BNIP3 signaling pathway.
    Xu WL; Wang SH; Sun WB; Gao J; Ding XM; Kong J; Xu L; Ke S
    BMB Rep; 2019 Apr; 52(4):277-282. PubMed ID: 30940322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. (-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
    Pei T; Meng Q; Han J; Sun H; Li L; Song R; Sun B; Pan S; Liang D; Liu L
    Oncotarget; 2016 Jul; 7(28):43475-43491. PubMed ID: 27259268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Exosome-transferred long non-coding RNA ASMTL-AS1 contributes to malignant phenotypes in residual hepatocellular carcinoma after insufficient radiofrequency ablation.
    Ma D; Gao X; Liu Z; Lu X; Ju H; Zhang N
    Cell Prolif; 2020 Sep; 53(9):e12795. PubMed ID: 32722884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.