These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 34189909)

  • 21. Comparison of kinetic parameters for drug oxidation rates and substrate inhibition potential mediated by cytochrome P450 3A4 and 3A5.
    Niwa T; Murayama N; Emoto C; Yamazaki H
    Curr Drug Metab; 2008 Jan; 9(1):20-33. PubMed ID: 18220568
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Interaction of lapatinib with cytochrome P450 3A5.
    Chan EC; New LS; Chua TB; Yap CW; Ho HK; Nelson SD
    Drug Metab Dispos; 2012 Jul; 40(7):1414-22. PubMed ID: 22511346
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Icotinib Induces Mechanism-Based Inactivation of Recombinant Human CYP3A4/5 Possibly via Heme Destruction by Ketene Intermediate.
    Sun C; Zhao H; Li W; Jia Y; Yang Y; Peng Y; Zheng J
    Drug Metab Dispos; 2021 Oct; 49(10):892-901. PubMed ID: 34312304
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Piperine Is a Mechanism-Based Inactivator of CYP3A.
    Cui T; Wang Q; Tian X; Zhang K; Peng Y; Zheng J
    Drug Metab Dispos; 2020 Feb; 48(2):123-134. PubMed ID: 31748224
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Differential oxidation of mifepristone by cytochromes P450 3A4 and 3A5: selective inactivation of P450 3A4.
    Khan KK; He YQ; Correia MA; Halpert JR
    Drug Metab Dispos; 2002 Sep; 30(9):985-90. PubMed ID: 12167563
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Bioactivation of a novel 2-methylindole-containing dual chemoattractant receptor-homologous molecule expressed on T-helper type-2 cells/D-prostanoid receptor antagonist leads to mechanism-based CYP3A inactivation: glutathione adduct characterization and prediction of in vivo drug-drug interaction.
    Wong SG; Fan PW; Subramanian R; Tonn GR; Henne KR; Johnson MG; Tadano Lohr M; Wong BK
    Drug Metab Dispos; 2010 May; 38(5):841-50. PubMed ID: 20100816
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Characterization of ritonavir-mediated inactivation of cytochrome P450 3A4.
    Rock BM; Hengel SM; Rock DA; Wienkers LC; Kunze KL
    Mol Pharmacol; 2014 Dec; 86(6):665-74. PubMed ID: 25274602
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Effect of Fluconazole and Itraconazole on the Pharmacokinetics of Erdafitinib in Healthy Adults: A Randomized, Open-Label, Drug-Drug Interaction Study.
    Poggesi I; Li LY; Jiao J; Hellemans P; Rasschaert F; de Zwart L; Snoeys J; De Meulder M; Mamidi RNVS; Ouellet D
    Eur J Drug Metab Pharmacokinet; 2020 Feb; 45(1):101-111. PubMed ID: 31673875
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Imidazoacridinone antitumor agent C-1311 as a selective mechanism-based inactivator of human cytochrome P450 1A2 and 3A4 isoenzymes.
    Potęga A; Fedejko-Kap B; Mazerska Z
    Pharmacol Rep; 2016 Aug; 68(4):663-70. PubMed ID: 27110874
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    He K; Woolf TF; Hollenberg PF
    J Pharmacol Exp Ther; 1999 Feb; 288(2):791-7. PubMed ID: 9918590
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mechanism-based inactivation of human cytochrome P450 1A2 and 3A4 isoenzymes by anti-tumor triazoloacridinone C-1305.
    Potęga A; Fedejko-Kap B; Mazerska Z
    Xenobiotica; 2016 Dec; 46(12):1056-1065. PubMed ID: 26928326
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Ritonavir analogues as a probe for deciphering the cytochrome P450 3A4 inhibitory mechanism.
    Sevrioukova IF; Poulos TL
    Curr Top Med Chem; 2014; 14(11):1348-55. PubMed ID: 24805065
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effect of Carbamazepine on the Pharmacokinetics of Erdafitinib in Healthy Participants.
    Jaiprasart P; Hellemans P; Jiao JJ; Dosne AG; De Meulder M; De Zwart L; Brees L; Zhu W
    Clin Pharmacol Drug Dev; 2024 Aug; 13(8):852-860. PubMed ID: 38740493
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib.
    Teng WC; Oh JW; New LS; Wahlin MD; Nelson SD; Ho HK; Chan EC
    Mol Pharmacol; 2010 Oct; 78(4):693-703. PubMed ID: 20624855
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
    Alvarez-Diez TM; Zheng J
    Chem Res Toxicol; 2004 Feb; 17(2):150-7. PubMed ID: 14967002
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The inactivation of cytochrome P450 3A5 by 17alpha-ethynylestradiol is cytochrome b5-dependent: metabolic activation of the ethynyl moiety leads to the formation of glutathione conjugates, a heme adduct, and covalent binding to the apoprotein.
    Lin HL; Hollenberg PF
    J Pharmacol Exp Ther; 2007 Apr; 321(1):276-87. PubMed ID: 17251390
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Interindividual Variation in CYP3A Activity Influences Lapatinib Bioactivation.
    Bissada JE; Truong V; Abouda AA; Wines KJ; Crouch RD; Jackson KD
    Drug Metab Dispos; 2019 Nov; 47(11):1257-1269. PubMed ID: 31492693
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Amelioration of mechanism-based inactivation of CYP3A4 by a H-PGDS inhibitor.
    Vaz RJ; Li Y; Munson M; Elliot M; Thurairatnam S
    Bioorg Med Chem Lett; 2018 Oct; 28(18):3046-3049. PubMed ID: 30115511
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5.
    Wright WC; Chenge J; Wang J; Girvan HM; Yang L; Chai SC; Huber AD; Wu J; Oladimeji PO; Munro AW; Chen T
    J Med Chem; 2020 Feb; 63(3):1415-1433. PubMed ID: 31965799
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Differential inhibition of cytochromes P450 3A4 and 3A5 by the newly synthesized coumarin derivatives 7-coumarin propargyl ether and 7-(4-trifluoromethyl)coumarin propargyl ether.
    Sridar C; Kent UM; Noon K; McCall A; Alworth B; Foroozesh M; Hollenberg PF
    Drug Metab Dispos; 2008 Nov; 36(11):2234-43. PubMed ID: 18653744
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.