BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

444 related articles for article (PubMed ID: 34210001)

  • 1. Enhancing B-Cell Malignancies-On Repurposing Enhancer Activity towards Cancer.
    Kasprzyk ME; Sura W; Dzikiewicz-Krawczyk A
    Cancers (Basel); 2021 Jun; 13(13):. PubMed ID: 34210001
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 7-[[(4-methyl-2-pyridinyl)amino](2-pyridinyl)methyl]-8-quinolinol (compound 30666) inhibits enhancer activity and reduces B-cell lymphoma growth - A question of specificity.
    Kasprzyk ME; Łosiewski W; Podralska M; Kazimierska M; Sura W; Dzikiewicz-Krawczyk A
    Eur J Pharmacol; 2021 Nov; 910():174505. PubMed ID: 34534532
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The value of detecting immunoglobulin gene rearrangements in the diagnosis of B-cell lymphoma.
    Lu C; He Q; Zhu W; Fu C; Zhou J; Tao Y; Liu S; Xiao D
    Oncotarget; 2017 Sep; 8(44):77009-77019. PubMed ID: 29100365
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery platform for inhibitors of IgH gene enhancer activity.
    Dolloff NG
    Cancer Biol Ther; 2019; 20(4):571-581. PubMed ID: 30481117
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.
    Gostissa M; Yan CT; Bianco JM; Cogné M; Pinaud E; Alt FW
    Nature; 2009 Dec; 462(7274):803-7. PubMed ID: 20010689
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers.
    Mikulasova A; Kent D; Trevisan-Herraz M; Karataraki N; Fung KTM; Ashby C; Cieslak A; Yaccoby S; van Rhee F; Zangari M; Thanendrarajan S; Schinke C; Morgan GJ; Asnafi V; Spicuglia S; Brackley CA; Corcoran AE; Hambleton S; Walker BA; Rico D; Russell LJ
    Genome Res; 2022 Jul; 32(7):1343-1354. PubMed ID: 34933939
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulatory elements in the immunoglobulin heavy chain gene 3'-enhancers induce c-myc deregulation and lymphomagenesis in murine B cells.
    Wang J; Boxer LM
    J Biol Chem; 2005 Apr; 280(13):12766-73. PubMed ID: 15687498
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci.
    Martín-Subero JI; Harder L; Gesk S; Schlegelberger B; Grote W; Martinez-Climent JA; Dyer MJ; Novo FJ; Calasanz MJ; Siebert R
    Int J Cancer; 2002 Mar; 98(3):470-4. PubMed ID: 11920602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.
    Ryan RJ; Drier Y; Whitton H; Cotton MJ; Kaur J; Issner R; Gillespie S; Epstein CB; Nardi V; Sohani AR; Hochberg EP; Bernstein BE
    Cancer Discov; 2015 Oct; 5(10):1058-71. PubMed ID: 26229090
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells.
    Hewitt SL; Farmer D; Marszalek K; Cadera E; Liang HE; Xu Y; Schlissel MS; Skok JA
    Nat Immunol; 2008 Apr; 9(4):396-404. PubMed ID: 18297074
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deletional analyses reveal an essential role for the hs3b/hs4 IgH 3' enhancer pair in an Ig-secreting but not an earlier-stage B cell line.
    Shi X; Eckhardt LA
    Int Immunol; 2001 Aug; 13(8):1003-12. PubMed ID: 11470770
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mouse Models of
    Ferrad M; Ghazzaui N; Issaoui H; Cook-Moreau J; Denizot Y
    Front Immunol; 2020; 11():1564. PubMed ID: 32793219
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Super enhancers as master gene regulators in the pathogenesis of hematologic malignancies.
    Dębek S; Juszczyński P
    Biochim Biophys Acta Rev Cancer; 2022 Mar; 1877(2):188697. PubMed ID: 35150791
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers.
    Andrews JM; Pyfrom SC; Schmidt JA; Koues OI; Kowalewski RA; Grams NR; Sun JJ; Berman LR; Duncavage EJ; Lee YS; Cashen AF; Oltz EM; Payton JE
    EBioMedicine; 2021 Sep; 71():103559. PubMed ID: 34461601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Addition of substitution of simian virus 40 enhancer sequences into the Moloney murine leukemia virus (M-MuLV) long terminal repeat yields infectious M-MuLV with altered biological properties.
    Hanecak R; Pattengale PK; Fan H
    J Virol; 1988 Jul; 62(7):2427-36. PubMed ID: 2836623
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 3' regulatory region induces MYC expression at the immature stage of B cell development.
    Yan Y; Park SS; Janz S; Eckhardt LA
    Genes Chromosomes Cancer; 2007 Oct; 46(10):950-9. PubMed ID: 17639584
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular cytogenetic analyses of immunoglobulin loci in nodular lymphocyte predominant Hodgkin's lymphoma reveal a recurrent IGH-BCL6 juxtaposition.
    Renné C; Martín-Subero JI; Hansmann ML; Siebert R
    J Mol Diagn; 2005 Aug; 7(3):352-6. PubMed ID: 16049307
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The molecular understanding of super-enhancer dysregulation in cancer.
    Yoshino S; Suzuki HI
    Nagoya J Med Sci; 2022 May; 84(2):216-229. PubMed ID: 35967935
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Immunoglobulin light chain gene rearrangements display hierarchy in absence of selection for functionality in precursor-B-ALL.
    van der Burg M; Barendregt BH; Szczepañski T; van Wering ER; Langerak AW; van Dongen JJ
    Leukemia; 2002 Aug; 16(8):1448-53. PubMed ID: 12145684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 3' IgH enhancer elements shift synergistic interactions during B cell development.
    Ong J; Stevens S; Roeder RG; Eckhardt LA
    J Immunol; 1998 May; 160(10):4896-903. PubMed ID: 9590237
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.