BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 34214079)

  • 1. eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants.
    Thornton AM; Fang L; Lo A; McSharry M; Haan D; O'Brien C; Berger AH; Giannakis M; Brooks AN
    PLoS Comput Biol; 2021 Jul; 17(7):e1009132. PubMed ID: 34214079
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An expression-based variant impact phenotyping protocol to predict the impact of gene variants in cell lines.
    Thornton AM; Tumu M; Brooks AN
    STAR Protoc; 2022 Sep; 3(3):101651. PubMed ID: 36092819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.
    Yu J; Yusoff PAM; Woutersen DTJ; Goh P; Harmston N; Smits R; Epstein DM; Virshup DM; Madan B
    Cancer Res; 2020 Dec; 80(24):5619-5632. PubMed ID: 33067269
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.
    Fang L; Ford-Roshon D; Russo M; O'Brien C; Xiong X; Gurjao C; Grandclaudon M; Raghavan S; Corsello SM; Carr SA; Udeshi ND; Berstler J; Sicinska E; Ng K; Giannakis M
    Nat Commun; 2022 Jun; 13(1):3181. PubMed ID: 35676246
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.
    Li S; Lavrijsen M; Bakker A; Magierowski M; Magierowska K; Liu P; Wang W; Peppelenbosch MP; Smits R
    Oncogene; 2020 Apr; 39(17):3458-3472. PubMed ID: 32103169
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface.
    Cho AR; Sul HJ; Kim YJ; Kim B; Zang DY
    Sci Rep; 2022 Apr; 12(1):7013. PubMed ID: 35487932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of RNF43 frameshift mutations that drive Wnt ligand- and R-spondin-dependent colon cancer.
    Yamamoto D; Oshima H; Wang D; Takeda H; Kita K; Lei X; Nakayama M; Murakami K; Ohama T; Takemura H; Toyota M; Suzuki H; Inaki N; Oshima M
    J Pathol; 2022 May; 257(1):39-52. PubMed ID: 35040131
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.
    Bond CE; McKeone DM; Kalimutho M; Bettington ML; Pearson SA; Dumenil TD; Wockner LF; Burge M; Leggett BA; Whitehall VL
    Oncotarget; 2016 Oct; 7(43):70589-70600. PubMed ID: 27661107
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis.
    Tu J; Park S; Yu W; Zhang S; Wu L; Carmon K; Liu QJ
    Sci Rep; 2019 Dec; 9(1):18557. PubMed ID: 31811196
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression.
    Eto T; Miyake K; Nosho K; Ohmuraya M; Imamura Y; Arima K; Kanno S; Fu L; Kiyozumi Y; Izumi D; Sugihara H; Hiyoshi Y; Miyamoto Y; Sawayama H; Iwatsuki M; Baba Y; Yoshida N; Furukawa T; Araki K; Baba H; Ishimoto T
    J Pathol; 2018 Aug; 245(4):445-455. PubMed ID: 29756208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAF
    Elez E; Ros J; Fernández J; Villacampa G; Moreno-Cárdenas AB; Arenillas C; Bernatowicz K; Comas R; Li S; Kodack DP; Fasani R; Garcia A; Gonzalo-Ruiz J; Piris-Gimenez A; Nuciforo P; Kerr G; Intini R; Montagna A; Germani MM; Randon G; Vivancos A; Smits R; Graus D; Perez-Lopez R; Cremolini C; Lonardi S; Pietrantonio F; Dienstmann R; Tabernero J; Toledo RA
    Nat Med; 2022 Oct; 28(10):2162-2170. PubMed ID: 36097219
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells.
    Neumeyer V; Grandl M; Dietl A; Brutau-Abia A; Allgäuer M; Kalali B; Zhang Y; Pan KF; Steiger K; Vieth M; Anton M; Mejías-Luque R; Gerhard M
    Carcinogenesis; 2019 Jun; 40(4):551-559. PubMed ID: 30380024
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers.
    Fennell LJ; Clendenning M; McKeone DM; Jamieson SH; Balachandran S; Borowsky J; Liu J; Kawamata F; Bond CE; Rosty C; Burge ME; Buchanan DD; Leggett BA; Whitehall VLJ
    Fam Cancer; 2018 Jan; 17(1):63-69. PubMed ID: 28573495
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer.
    Seeber A; Battaglin F; Zimmer K; Kocher F; Baca Y; Xiu J; Spizzo G; Novotny-Diermayr V; Rieder D; Puccini A; Swensen J; Ellis M; Goldberg RM; Grothey A; Shields AF; Marshall JL; Weinberg BA; Sackstein PE; Lim KH; Tan GS; Nabhan C; Korn WM; Amann A; Trajanoski Z; Berger MD; Lou E; Wolf D; Lenz HJ
    Clin Cancer Res; 2022 May; 28(9):1863-1870. PubMed ID: 35254413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.
    Yan HHN; Lai JCW; Ho SL; Leung WK; Law WL; Lee JFY; Chan AKW; Tsui WY; Chan ASY; Lee BCH; Yue SSK; Man AHY; Clevers H; Yuen ST; Leung SY
    Gut; 2017 Sep; 66(9):1645-1656. PubMed ID: 27329244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
    Jiang X; Hao HX; Growney JD; Woolfenden S; Bottiglio C; Ng N; Lu B; Hsieh MH; Bagdasarian L; Meyer R; Smith TR; Avello M; Charlat O; Xie Y; Porter JA; Pan S; Liu J; McLaughlin ME; Cong F
    Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12649-54. PubMed ID: 23847203
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Next-generation sequencing reveals heterogeneous genetic alterations in key signaling pathways of mismatch repair deficient colorectal carcinomas.
    Wang J; Li R; He Y; Yi Y; Wu H; Liang Z
    Mod Pathol; 2020 Dec; 33(12):2591-2601. PubMed ID: 32620917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNF43 mutation analysis in serrated polyposis, sporadic serrated polyps and Lynch syndrome polyps.
    van Herwaarden YJ; Koggel LM; Simmer F; Vink-Börger EM; Dura P; Meijer GA; Nagengast FM; Hoogerbrugge N; Bisseling TM; Nagtegaal ID
    Histopathology; 2021 Apr; 78(5):749-758. PubMed ID: 33098683
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ring Finger 43 Hot-spot Frameshift Mutation G659V in Colorectal Cancer Patients: Report from a Tertiary Cancer Care Hospital in North India.
    Vasudevan S; Mehta A; Karki D; Kumar D
    Int J Appl Basic Med Res; 2024; 14(1):17-22. PubMed ID: 38504846
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells.
    Radaszkiewicz T; Bryja V
    Cell Commun Signal; 2020 Jun; 18(1):91. PubMed ID: 32527265
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.