BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 34219248)

  • 1. Impact of age, hypercholesterolemia, and the vitamin D receptor on brain endogenous β-amyloid peptide accumulation in mice.
    Peng HB; Bukuroshi P; Durk MR; Grootendorst P; Yan X; Pan SR; de Lannoy IAM; Pang KS
    Biopharm Drug Dispos; 2021 Sep; 42(8):372-388. PubMed ID: 34219248
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Brain regional correlation of amyloid-β with synapses and apolipoprotein E in non-demented individuals: potential mechanisms underlying regional vulnerability to amyloid-β accumulation.
    Shinohara M; Petersen RC; Dickson DW; Bu G
    Acta Neuropathol; 2013 Apr; 125(4):535-47. PubMed ID: 23371365
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice.
    Thirumangalakudi L; Prakasam A; Zhang R; Bimonte-Nelson H; Sambamurti K; Kindy MS; Bhat NR
    J Neurochem; 2008 Jul; 106(1):475-85. PubMed ID: 18410513
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of beta-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer's disease.
    Jaya Prasanthi RP; Schommer E; Thomasson S; Thompson A; Feist G; Ghribi O
    Mech Ageing Dev; 2008 Nov; 129(11):649-55. PubMed ID: 18845178
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymoquinone-rich fraction nanoemulsion (TQRFNE) decreases Aβ40 and Aβ42 levels by modulating APP processing, up-regulating IDE and LRP1, and down-regulating BACE1 and RAGE in response to high fat/cholesterol diet-induced rats.
    Ismail N; Ismail M; Azmi NH; Bakar MFA; Yida Z; Abdullah MA; Basri H
    Biomed Pharmacother; 2017 Nov; 95():780-788. PubMed ID: 28892789
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
    Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
    Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GEPT extract reduces Abeta deposition by regulating the balance between production and degradation of Abeta in APPV717I transgenic mice.
    Tian J; Shi J; Zhang L; Yin J; Hu Q; Xu Y; Sheng S; Wang P; Ren Y; Wang R; Wang Y
    Curr Alzheimer Res; 2009 Apr; 6(2):118-31. PubMed ID: 19355846
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
    Fanaee-Danesh E; Gali CC; Tadic J; Zandl-Lang M; Carmen Kober A; Agujetas VR; de Dios C; Tam-Amersdorfer C; Stracke A; Albrecher NM; Manavalan APC; Reiter M; Sun Y; Colell A; Madeo F; Malle E; Panzenboeck U
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2224-2245. PubMed ID: 31055081
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The contribution of activated astrocytes to Aβ production: implications for Alzheimer's disease pathogenesis.
    Zhao J; O'Connor T; Vassar R
    J Neuroinflammation; 2011 Nov; 8():150. PubMed ID: 22047170
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of vitamin D receptor inhibits Tau phosphorylation is associated with reduction of iron accumulation in APP/PS1 transgenic mice.
    Wu TY; Zhao LX; Zhang YH; Fan YG
    Neurochem Int; 2022 Feb; 153():105260. PubMed ID: 34953963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High-Phytate Diets Increase Amyloid β Deposition and Apoptotic Neuronal Cell Death in a Rat Model.
    Kim HJ; Jung YS; Jung YJ; Kim OH; Oh BC
    Nutrients; 2021 Dec; 13(12):. PubMed ID: 34959925
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Changes in astrocyte functional markers and β-amyloid metabolism-related proteins in the early stages of hypercholesterolemia.
    Chen YL; Wang LM; Chen Y; Gao JY; Marshall C; Cai ZY; Hu G; Xiao M
    Neuroscience; 2016 Mar; 316():178-91. PubMed ID: 26724580
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).
    Do TM; Dodacki A; Alata W; Calon F; Nicolic S; Scherrmann JM; Farinotti R; Bourasset F
    J Alzheimers Dis; 2016; 49(2):287-300. PubMed ID: 26484906
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.
    Sadleir KR; Eimer WA; Kaufman RJ; Osten P; Vassar R
    PLoS One; 2014; 9(7):e101643. PubMed ID: 24992504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduction of Liver X Receptor β expression in primary rat neurons by antisense oligodeoxynucleotides decreases secreted amyloid β levels.
    Wang Q; Wang S; Shi Y; Yao M; Hou L; Jiang L
    Neurosci Lett; 2014 Feb; 561():146-50. PubMed ID: 24394905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Energy inhibition elevates beta-secretase levels and activity and is potentially amyloidogenic in APP transgenic mice: possible early events in Alzheimer's disease pathogenesis.
    Velliquette RA; O'Connor T; Vassar R
    J Neurosci; 2005 Nov; 25(47):10874-83. PubMed ID: 16306400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.