255 related articles for article (PubMed ID: 34228709)
1. Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
Soriano I; Vazquez E; De Leon N; Bertrand S; Heitzer E; Toumazou S; Bo Z; Palles C; Pai CC; Humphrey TC; Tomlinson I; Cotterill S; Kearsey SE
PLoS Genet; 2021 Jul; 17(7):e1009526. PubMed ID: 34228709
[TBL] [Abstract][Full Text] [Related]
2. dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants.
Williams LN; Marjavaara L; Knowels GM; Schultz EM; Fox EJ; Chabes A; Herr AJ
Proc Natl Acad Sci U S A; 2015 May; 112(19):E2457-66. PubMed ID: 25827226
[TBL] [Abstract][Full Text] [Related]
3. DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer.
Church DN; Briggs SE; Palles C; Domingo E; Kearsey SJ; Grimes JM; Gorman M; Martin L; Howarth KM; Hodgson SV; ; Kaur K; Taylor J; Tomlinson IP
Hum Mol Genet; 2013 Jul; 22(14):2820-8. PubMed ID: 23528559
[TBL] [Abstract][Full Text] [Related]
4. RecQ DNA Helicase Rqh1 Promotes Rad3
Ahamad N; Khan S; Xu YJ
Mol Cell Biol; 2020 Aug; 40(17):. PubMed ID: 32541066
[TBL] [Abstract][Full Text] [Related]
5. Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles.
Herzog M; Alonso-Perez E; Salguero I; Warringer J; Adams DJ; Jackson SP; Puddu F
Nucleic Acids Res; 2021 Apr; 49(7):3919-3931. PubMed ID: 33764464
[TBL] [Abstract][Full Text] [Related]
6. Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication.
Shinbrot E; Henninger EE; Weinhold N; Covington KR; Göksenin AY; Schultz N; Chao H; Doddapaneni H; Muzny DM; Gibbs RA; Sander C; Pursell ZF; Wheeler DA
Genome Res; 2014 Nov; 24(11):1740-50. PubMed ID: 25228659
[TBL] [Abstract][Full Text] [Related]
7. Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.
Fang H; Barbour JA; Poulos RC; Katainen R; Aaltonen LA; Wong JWH
PLoS Genet; 2020 Feb; 16(2):e1008572. PubMed ID: 32012149
[TBL] [Abstract][Full Text] [Related]
8. DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast.
Handa T; Kanke M; Takahashi TS; Nakagawa T; Masukata H
Mol Biol Cell; 2012 Aug; 23(16):3240-53. PubMed ID: 22718908
[TBL] [Abstract][Full Text] [Related]
9. Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.
McDonald KR; Guise AJ; Pourbozorgi-Langroudi P; Cristea IM; Zakian VA; Capra JA; Sabouri N
PLoS Genet; 2016 Sep; 12(9):e1006238. PubMed ID: 27611590
[TBL] [Abstract][Full Text] [Related]
10. Schizosaccharomyces pombe cells lacking the amino-terminal catalytic domains of DNA polymerase epsilon are viable but require the DNA damage checkpoint control.
Feng W; D'Urso G
Mol Cell Biol; 2001 Jul; 21(14):4495-504. PubMed ID: 11416129
[TBL] [Abstract][Full Text] [Related]
11. Schizosaccharomyces pombe cdc20+ encodes DNA polymerase epsilon and is required for chromosomal replication but not for the S phase checkpoint.
D'Urso G; Nurse P
Proc Natl Acad Sci U S A; 1997 Nov; 94(23):12491-6. PubMed ID: 9356477
[TBL] [Abstract][Full Text] [Related]
12. The somatic POLE P286R mutation defines a unique subclass of colorectal cancer featuring hypermutation, representing a potential genomic biomarker for immunotherapy.
Ahn SM; Ansari AA; Kim J; Kim D; Chun SM; Kim J; Kim TW; Park I; Yu CS; Jang SJ
Oncotarget; 2016 Oct; 7(42):68638-68649. PubMed ID: 27612425
[TBL] [Abstract][Full Text] [Related]
13. Evidence for interplay among yeast replicative DNA polymerases alpha, delta and epsilon from studies of exonuclease and polymerase active site mutations.
Pavlov YI; Maki S; Maki H; Kunkel TA
BMC Biol; 2004 May; 2():11. PubMed ID: 15163346
[TBL] [Abstract][Full Text] [Related]
14. DNA polymerase epsilon encoded by cdc20+ is required for chromosomal DNA replication in the fission yeast Schizosaccharomyces pombe.
Sugino A; Ohara T; Sebastian J; Nakashima N; Araki H
Genes Cells; 1998 Feb; 3(2):99-110. PubMed ID: 9605404
[TBL] [Abstract][Full Text] [Related]
15. Interpretation of somatic POLE mutations in endometrial carcinoma.
León-Castillo A; Britton H; McConechy MK; McAlpine JN; Nout R; Kommoss S; Brucker SY; Carlson JW; Epstein E; Rau TT; Bosse T; Church DN; Gilks CB
J Pathol; 2020 Mar; 250(3):323-335. PubMed ID: 31829442
[TBL] [Abstract][Full Text] [Related]
16. Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in
Barbari SR; Kane DP; Moore EA; Shcherbakova PV
G3 (Bethesda); 2018 Mar; 8(3):1019-1029. PubMed ID: 29352080
[TBL] [Abstract][Full Text] [Related]
17. Human Pol ε-dependent replication errors and the influence of mismatch repair on their correction.
Agbor AA; Göksenin AY; LeCompte KG; Hans SH; Pursell ZF
DNA Repair (Amst); 2013 Nov; 12(11):954-63. PubMed ID: 24051051
[TBL] [Abstract][Full Text] [Related]
18. Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.
Temko D; Van Gool IC; Rayner E; Glaire M; Makino S; Brown M; Chegwidden L; Palles C; Depreeuw J; Beggs A; Stathopoulou C; Mason J; Baker AM; Williams M; Cerundolo V; Rei M; Taylor JC; Schuh A; Ahmed A; Amant F; Lambrechts D; Smit VT; Bosse T; Graham TA; Church DN; Tomlinson I
J Pathol; 2018 Jul; 245(3):283-296. PubMed ID: 29604063
[TBL] [Abstract][Full Text] [Related]
19. Identification and cloning of two putative subunits of DNA polymerase epsilon in fission yeast.
Spiga MG; D'Urso G
Nucleic Acids Res; 2004; 32(16):4945-53. PubMed ID: 15388803
[TBL] [Abstract][Full Text] [Related]
20. Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk.
Rocque MJ; Leipart V; Kumar Singh A; Mur P; Olsen MF; Engebretsen LF; Martin-Ramos E; Aligué R; Sætrom P; Valle L; Drabløs F; Otterlei M; Sjursen W
Mol Genet Genomics; 2023 May; 298(3):555-566. PubMed ID: 36856825
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
