122 related articles for article (PubMed ID: 34229068)
1. Contextualization of causal regulatory networks from toxicogenomics data applied to drug-induced liver injury.
Trairatphisan P; de Souza TM; Kleinjans J; Jennen D; Saez-Rodriguez J
Toxicol Lett; 2021 Oct; 350():40-51. PubMed ID: 34229068
[TBL] [Abstract][Full Text] [Related]
2. Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.
Laifenfeld D; Qiu L; Swiss R; Park J; Macoritto M; Will Y; Younis HS; Lawton M
Toxicol Sci; 2014 Jan; 137(1):234-48. PubMed ID: 24136188
[TBL] [Abstract][Full Text] [Related]
3. From expression footprints to causal pathways: contextualizing large signaling networks with CARNIVAL.
Liu A; Trairatphisan P; Gjerga E; Didangelos A; Barratt J; Saez-Rodriguez J
NPJ Syst Biol Appl; 2019; 5():40. PubMed ID: 31728204
[TBL] [Abstract][Full Text] [Related]
4. Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.
Hanafusa H; Morikawa Y; Uehara T; Kaneto M; Ono A; Yamada H; Ohno Y; Urushidani T
Toxicology; 2014 Oct; 324():43-54. PubMed ID: 25051504
[TBL] [Abstract][Full Text] [Related]
5. Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities.
Podtelezhnikov AA; Monroe JJ; Aslamkhan AG; Pearson K; Qin C; Tamburino AM; Loboda AP; Glaab WE; Sistare FD; Tanis KQ
Toxicol Sci; 2020 May; 175(1):98-112. PubMed ID: 32119089
[TBL] [Abstract][Full Text] [Related]
6. A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury.
Kohonen P; Parkkinen JA; Willighagen EL; Ceder R; Wennerberg K; Kaski S; Grafström RC
Nat Commun; 2017 Jul; 8():15932. PubMed ID: 28671182
[TBL] [Abstract][Full Text] [Related]
7. DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds.
Hendrickx DM; Souza T; Jennen DGJ; Kleinjans JCS
Arch Toxicol; 2017 Jun; 91(6):2343-2352. PubMed ID: 28032149
[TBL] [Abstract][Full Text] [Related]
8. The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment.
Callegaro G; Kunnen SJ; Trairatphisan P; Grosdidier S; Niemeijer M; den Hollander W; Guney E; Piñero Gonzalez J; Furlong L; Webster YW; Saez-Rodriguez J; Sutherland JJ; Mollon J; Stevens JL; van de Water B
Arch Toxicol; 2021 Dec; 95(12):3745-3775. PubMed ID: 34626214
[TBL] [Abstract][Full Text] [Related]
9. A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury.
Wijaya LS; Gabor A; Pot IE; van de Have L; Saez-Rodriguez J; Stevens JL; Le Dévédec SE; Callegaro G; van de Water B
Toxicol Sci; 2024 Feb; 198(1):14-30. PubMed ID: 38015832
[TBL] [Abstract][Full Text] [Related]
10. A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database.
Rueda-Zárate HA; Imaz-Rosshandler I; Cárdenas-Ovando RA; Castillo-Fernández JE; Noguez-Monroy J; Rangel-Escareño C
PLoS One; 2017; 12(4):e0176284. PubMed ID: 28448553
[TBL] [Abstract][Full Text] [Related]
11. Is toxicogenomics a more reliable and sensitive biomarker than conventional indicators from rats to predict drug-induced liver injury in humans?
Zhang M; Chen M; Tong W
Chem Res Toxicol; 2012 Jan; 25(1):122-9. PubMed ID: 22122743
[TBL] [Abstract][Full Text] [Related]
12. Systems toxicology used in nanotoxicology: mechanistic insights into the hepatotoxicity of nano-copper particles from toxicogenomics.
Yang B; Wang Q; Lei R; Wu C; Shi C; Wang Q; Yuan Y; Wang Y; Luo Y; Hu Z; Ma H; Liao M
J Nanosci Nanotechnol; 2010 Dec; 10(12):8527-37. PubMed ID: 21121362
[TBL] [Abstract][Full Text] [Related]
13. Application of the comparison approach to open TG-GATEs: A useful toxicogenomics tool for detecting modes of action in chemical risk assessment.
Heusinkveld HJ; Wackers PFK; Schoonen WG; van der Ven L; Pennings JLA; Luijten M
Food Chem Toxicol; 2018 Nov; 121():115-123. PubMed ID: 30096367
[TBL] [Abstract][Full Text] [Related]
14. Benchmarking causal reasoning algorithms for gene expression-based compound mechanism of action analysis.
Hosseini-Gerami L; Higgins IA; Collier DA; Laing E; Evans D; Broughton H; Bender A
BMC Bioinformatics; 2023 Apr; 24(1):154. PubMed ID: 37072707
[TBL] [Abstract][Full Text] [Related]
15. Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes.
Grinberg M; Stöber RM; Albrecht W; Edlund K; Schug M; Godoy P; Cadenas C; Marchan R; Lampen A; Braeuning A; Buhrke T; Leist M; Oberemm A; Hellwig B; Kamp H; Gardner I; Escher S; Taboureau O; Aguayo-Orozco A; Sachinidis A; Ellinger-Ziegelbauer H; Rahnenführer J; Hengstler JG
Arch Toxicol; 2018 Dec; 92(12):3517-3533. PubMed ID: 30511339
[TBL] [Abstract][Full Text] [Related]
16. Gene set-level network analysis using a toxicogenomics database.
Kiyosawa N; Manabe S; Sanbuissho A; Yamoto T
Genomics; 2010 Jul; 96(1):39-49. PubMed ID: 20363313
[TBL] [Abstract][Full Text] [Related]
17. A novel transcriptomics based in vitro method to compare and predict hepatotoxicity based on mode of action.
De Abrew KN; Overmann GJ; Adams RL; Tiesman JP; Dunavent J; Shan YK; Carr GJ; Daston GP; Naciff JM
Toxicology; 2015 Feb; 328():29-39. PubMed ID: 25475144
[TBL] [Abstract][Full Text] [Related]
18. Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy.
Hirode M; Omura K; Kiyosawa N; Uehara T; Shimuzu T; Ono A; Miyagishima T; Nagao T; Ohno Y; Urushidani T
J Toxicol Sci; 2009 Jun; 34(3):281-93. PubMed ID: 19483382
[TBL] [Abstract][Full Text] [Related]
19. Chinese herbal formula Fuzheng Huayu alleviates CCl
Dong S; Cai FF; Chen QL; Song YN; Sun Y; Wei B; Li XY; Hu YY; Liu P; Su SB
Acta Pharmacol Sin; 2018 Jun; 39(6):930-941. PubMed ID: 29094729
[TBL] [Abstract][Full Text] [Related]
20. Species-specific differences in coumarin-induced hepatotoxicity as an example toxicogenomics-based approach to assessing risk of toxicity to humans.
Uehara T; Kiyosawa N; Shimizu T; Omura K; Hirode M; Imazawa T; Mizukawa Y; Ono A; Miyagishima T; Nagao T; Urushidani T
Hum Exp Toxicol; 2008 Jan; 27(1):23-35. PubMed ID: 18480146
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
