BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 34233076)

  • 1. Design, synthesis, and primary activity assays of baicalein derivatives as cyclin-dependent kinase 1 inhibitors.
    Mou J; Qiu S; Chen D; Deng Y; Tekleab T
    Chem Biol Drug Des; 2021 Oct; 98(4):639-654. PubMed ID: 34233076
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design of new disubstituted imidazo[1,2-
    Elie J; Feizbakhsh O; Desban N; Josselin B; Baratte B; Bescond A; Duez J; Fant X; Bach S; Marie D; Place M; Ben Salah S; Chartier A; Berteina-Raboin S; Chaikuad A; Knapp S; Carles F; Bonnet P; Buron F; Routier S; Ruchaud S
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1840-1853. PubMed ID: 33040634
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nitrogen-containing flavonoids as CDK1/Cyclin B inhibitors: design, synthesis, and biological evaluation.
    Liu T; Xu Z; He Q; Chen Y; Yang B; Hu Y
    Bioorg Med Chem Lett; 2007 Jan; 17(1):278-81. PubMed ID: 17085048
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT.
    Chao JI; Su WC; Liu HF
    Mol Cancer Ther; 2007 Nov; 6(11):3039-48. PubMed ID: 18025287
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors.
    Fu Y; Tang S; Su Y; Lan X; Ye Y; Zha C; Li L; Cao J; Chen Y; Jiang L; Huang Y; Ding J; Geng M; Huang M; Wan H
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5332-5336. PubMed ID: 29074254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells.
    Pecoraro C; Parrino B; Cascioferro S; Puerta A; Avan A; Peters GJ; Diana P; Giovannetti E; Carbone D
    Molecules; 2021 Dec; 27(1):. PubMed ID: 35011251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Eco-friendly sequential one-pot synthesis, molecular docking, and anticancer evaluation of arylidene-hydrazinyl-thiazole derivatives as CDK2 inhibitors.
    El-Naggar AM; El-Hashash MA; Elkaeed EB
    Bioorg Chem; 2021 Mar; 108():104615. PubMed ID: 33484942
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole-Indole Conjugates as Anticancer CDK Inhibitors.
    Al-Warhi T; El Kerdawy AM; Aljaeed N; Ismael OE; Ayyad RR; Eldehna WM; Abdel-Aziz HA; Al-Ansary GH
    Molecules; 2020 Apr; 25(9):. PubMed ID: 32349307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency.
    Ibrahim N; Bonnet P; Brion JD; Peyrat JF; Bignon J; Levaique H; Josselin B; Robert T; Colas P; Bach S; Messaoudi S; Alami M; Hamze A
    Eur J Med Chem; 2020 Aug; 199():112355. PubMed ID: 32402934
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, Synthesis, and Activity Assays of Cyclin-Dependent Kinase 1 Inhibitors With Flavone Scaffolds.
    Fu L; Mou J; Deng Y; Ren X; Qiu S
    Front Chem; 2022; 10():940427. PubMed ID: 36003621
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of guanidino analogues of roscovitine.
    Dolečková I; Cesnek M; Dračinský M; Brynda J; Voller J; Janeba Z; Kryštof V
    Eur J Med Chem; 2013 Apr; 62():443-52. PubMed ID: 23399722
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity.
    Schultz C; Link A; Leost M; Zaharevitz DW; Gussio R; Sausville EA; Meijer L; Kunick C
    J Med Chem; 1999 Jul; 42(15):2909-19. PubMed ID: 10425100
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA; Sakr H; Ayyad RRA; El-Adl K; Ali MM; Khedr F
    Anticancer Agents Med Chem; 2018; 18(8):1184-1196. PubMed ID: 29651967
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Scaffold Repurposing of In-House Small Molecule Candidates Leads to Discovery of First-in-Class CDK-1/HER-2 Dual Inhibitors: In Vitro and In Silico Screening.
    Elkamhawy A; Ammar UM; Paik S; Abdellattif MH; Elsherbeny MH; Lee K; Roh EJ
    Molecules; 2021 Sep; 26(17):. PubMed ID: 34500757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1,3-diphenyl-1H-pyrazole-4-carboxamides as CDK1/Cdc2 inhibitors.
    Ganga Reddy V; Srinivasa Reddy T; Lakshma Nayak V; Prasad B; Reddy AP; Ravikumar A; Taj S; Kamal A
    Eur J Med Chem; 2016 Oct; 122():164-177. PubMed ID: 27344493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: synthesis and biological effects.
    Kim KS; Sack JS; Tokarski JS; Qian L; Chao ST; Leith L; Kelly YF; Misra RN; Hunt JT; Kimball SD; Humphreys WG; Wautlet BS; Mulheron JG; Webster KR
    J Med Chem; 2000 Nov; 43(22):4126-34. PubMed ID: 11063609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity.
    Wang J; Li T; Zhao T; Wu T; Liu C; Ding H; Li Z; Bian J
    Eur J Med Chem; 2019 Sep; 178():782-801. PubMed ID: 31238183
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of Cyclin-Dependent Kinase 1/2 for Anticancer Treatment.
    Mou J; Chen D; Deng Y
    Med Chem; 2020; 16(3):307-325. PubMed ID: 31241436
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Homology modeling, molecular dynamic simulation and docking studies of cyclin dependent kinase 1.
    Zhang L; Zhu H; Wang Q; Fang H; Xu W; Li M
    J Mol Model; 2011 Feb; 17(2):219-26. PubMed ID: 20419498
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular models of cyclin-dependent kinase 1 complexed with inhibitors.
    Canduri F; Uchoa HB; de Azevedo WF
    Biochem Biophys Res Commun; 2004 Nov; 324(2):661-6. PubMed ID: 15474478
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.