BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 34241577)

  • 1. Structural and functional insights into human tRNA guanine transgylcosylase.
    Sievers K; Welp L; Urlaub H; Ficner R
    RNA Biol; 2021 Oct; 18(sup1):382-396. PubMed ID: 34241577
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
    Johannsson S; Neumann P; Ficner R
    Biomolecules; 2018 Aug; 8(3):. PubMed ID: 30149595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of specificity determinants in bacterial tRNA-guanine transglycosylase reveals queuine, the substrate of its eucaryotic counterpart, as inhibitor.
    Biela I; Tidten-Luksch N; Immekus F; Glinca S; Nguyen TX; Gerber HD; Heine A; Klebe G; Reuter K
    PLoS One; 2013; 8(5):e64240. PubMed ID: 23704982
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
    Romier C; Reuter K; Suck D; Ficner R
    Biochemistry; 1996 Dec; 35(49):15734-9. PubMed ID: 8961936
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase.
    Sievers K; Neumann P; Sušac L; Da Vela S; Graewert M; Trowitzsch S; Svergun D; Tampé R; Ficner R
    Structure; 2024 Mar; 32(3):316-327.e5. PubMed ID: 38181786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure.
    Chen YC; Kelly VP; Stachura SV; Garcia GA
    RNA; 2010 May; 16(5):958-68. PubMed ID: 20354154
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homodimer Architecture of QTRT2, the Noncatalytic Subunit of the Eukaryotic tRNA-Guanine Transglycosylase.
    Behrens C; Biela I; Petiot-Bécard S; Botzanowski T; Cianférani S; Sager CP; Klebe G; Heine A; Reuter K
    Biochemistry; 2018 Jul; 57(26):3953-3965. PubMed ID: 29862811
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interaction.
    Ritschel T; Atmanene C; Reuter K; Van Dorsselaer A; Sanglier-Cianferani S; Klebe G
    J Mol Biol; 2009 Nov; 393(4):833-47. PubMed ID: 19627989
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase.
    Sebastiani M; Behrens C; Dörr S; Gerber HD; Benazza R; Hernandez-Alba O; Cianférani S; Klebe G; Heine A; Reuter K
    ACS Chem Biol; 2022 Aug; 17(8):2229-2247. PubMed ID: 35815944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. tRNA-guanine transglycosylase from Escherichia coli: recognition of full-length 'queuine-cognate' tRNAs.
    Kung FL; Garcia GA
    FEBS Lett; 1998 Jul; 431(3):427-32. PubMed ID: 9714557
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of aspartic acid 143 in E. coli tRNA-guanine transglycosylase: insights from mutagenesis studies and computational modeling.
    Todorov KA; Tan XJ; Nonekowski ST; Garcia GA; Carlson HA
    Biophys J; 2005 Sep; 89(3):1965-77. PubMed ID: 15951383
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Soaking suggests "alternative facts": Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibition.
    Ehrmann FR; Stojko J; Metz A; Debaene F; Barandun LJ; Heine A; Diederich F; Cianférani S; Reuter K; Klebe G
    PLoS One; 2017; 12(4):e0175723. PubMed ID: 28419165
    [TBL] [Abstract][Full Text] [Related]  

  • 13. tRNA-guanine transglycosylase from Escherichia coli: gross tRNA structural requirements for recognition.
    Curnow AW; Kung FL; Koch KA; Garcia GA
    Biochemistry; 1993 May; 32(19):5239-46. PubMed ID: 8494901
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding.
    Stengl B; Meyer EA; Heine A; Brenk R; Diederich F; Klebe G
    J Mol Biol; 2007 Jul; 370(3):492-511. PubMed ID: 17524419
    [TBL] [Abstract][Full Text] [Related]  

  • 15. tRNA recognition by tRNA-guanine transglycosylase from Escherichia coli: the role of U33 in U-G-U sequence recognition.
    Nonekowski ST; Garcia GA
    RNA; 2001 Oct; 7(10):1432-41. PubMed ID: 11680848
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.
    Romier C; Reuter K; Suck D; Ficner R
    EMBO J; 1996 Jun; 15(11):2850-7. PubMed ID: 8654383
    [TBL] [Abstract][Full Text] [Related]  

  • 17. tRNA-guanine transglycosylase from Escherichia coli. Overexpression, purification and quaternary structure.
    Garcia GA; Koch KA; Chong S
    J Mol Biol; 1993 May; 231(2):489-97. PubMed ID: 8323579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNA via a sequential bi-bi mechanism.
    Alqasem MA; Fergus C; Southern JM; Connon SJ; Kelly VP
    Chem Commun (Camb); 2020 Apr; 56(27):3915-3918. PubMed ID: 32149287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli.
    Kittendorf JD; Sgraja T; Reuter K; Klebe G; Garcia GA
    J Biol Chem; 2003 Oct; 278(43):42369-76. PubMed ID: 12909636
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Nguyen A; Gemmecker G; Softley CA; Movsisyan LD; Pfaffeneder T; Heine A; Reuter K; Diederich F; Sattler M; Klebe G
    ACS Chem Biol; 2022 Jul; 17(7):1745-1755. PubMed ID: 35763700
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.