BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 34241977)

  • 1. Computational Designing and Prediction of ADMET Properties of Four Novel Imidazole-based Drug Candidates Inhibiting Heme Oxygenase-1 Causing Cancers.
    Rahman M; Talukder A; Akter R
    Mol Inform; 2021 Oct; 40(10):e2060033. PubMed ID: 34241977
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heme oxygenase inhibition by 1-aryl-2-(1h-imidazol-1-yl/1h-1,2,4-triazol-1-yl)ethanones and their derivatives.
    Roman G; Vlahakis JZ; Vukomanovic D; Nakatsu K; Szarek WA
    ChemMedChem; 2010 Sep; 5(9):1541-55. PubMed ID: 20652928
    [TBL] [Abstract][Full Text] [Related]  

  • 3. X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors.
    Rahman MN; Vlahakis JZ; Szarek WA; Nakatsu K; Jia Z
    J Med Chem; 2008 Oct; 51(19):5943-52. PubMed ID: 18798608
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors.
    Vlahakis JZ; Kinobe RT; Bowers RJ; Brien JF; Nakatsu K; Szarek WA
    J Med Chem; 2006 Jul; 49(14):4437-41. PubMed ID: 16821802
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heme oxygenase inhibition by 2-oxy-substituted 1-azolyl-4-phenylbutanes: effect of variation of the azole moiety. X-ray crystal structure of human heme oxygenase-1 in complex with 4-phenyl-1-(1H-1,2,4-triazol-1-yl)-2-butanone.
    Roman G; Rahman MN; Vukomanovic D; Jia Z; Nakatsu K; Szarek WA
    Chem Biol Drug Des; 2010 Jan; 75(1):68-90. PubMed ID: 19954435
    [TBL] [Abstract][Full Text] [Related]  

  • 6. X-ray crystallographic and biochemical characterization of the inhibitory action of an imidazole-dioxolane compound on heme oxygenase.
    Sugishima M; Higashimoto Y; Oishi T; Takahashi H; Sakamoto H; Noguchi M; Fukuyama K
    Biochemistry; 2007 Feb; 46(7):1860-7. PubMed ID: 17253780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products.
    Floresta G; Amata E; Gentile D; Romeo G; Marrazzo A; Pittalà V; Salerno L; Rescifina A
    Mar Drugs; 2019 Feb; 17(2):. PubMed ID: 30759842
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells.
    Salerno L; Sorrenti V; Pittalà V; Consoli V; Modica MN; Romeo G; Marrazzo A; Giuliano M; Zajdel P; Vanella L; Intagliata S
    ChemMedChem; 2023 Apr; 18(8):e202300047. PubMed ID: 36756924
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: effect of halogen substitution in the phenyl ring.
    Roman G; Riley JG; Vlahakis JZ; Kinobe RT; Brien JF; Nakatsu K; Szarek WA
    Bioorg Med Chem; 2007 May; 15(9):3225-34. PubMed ID: 17339115
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.
    Salerno L; Pittalà V; Romeo G; Modica MN; Marrazzo A; Siracusa MA; Sorrenti V; Di Giacomo C; Vanella L; Parayath NN; Greish K
    Eur J Med Chem; 2015; 96():162-72. PubMed ID: 25874340
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heme oxygenase inhibition by α-(1H-imidazol-1-yl)-ω-phenylalkanes: effect of introduction of heteroatoms in the alkyl linker.
    Vlahakis JZ; Lazar C; Roman G; Vukomanovic D; Nakatsu K; Szarek WA
    ChemMedChem; 2012 May; 7(5):897-902. PubMed ID: 22431362
    [TBL] [Abstract][Full Text] [Related]  

  • 12. How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.
    Carletta A; Tilborg A; Moineaux L; de Ruyck J; Basile L; Salerno L; Romeo G; Wouters J; Guccione S
    Acta Crystallogr B Struct Sci Cryst Eng Mater; 2015 Aug; 71(Pt 4):447-54. PubMed ID: 26208625
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation.
    Greish KF; Salerno L; Al Zahrani R; Amata E; Modica MN; Romeo G; Marrazzo A; Prezzavento O; Sorrenti V; Rescifina A; Floresta G; Intagliata S; Pittalà V
    Molecules; 2018 May; 23(5):. PubMed ID: 29783634
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chromatograpic resolution of phenylethanolic-azole racemic compounds highlighted stereoselective inhibition of heme oxygenase-1 by (R)-enantiomers.
    Floresta G; Carotti A; Ianni F; Sorrenti V; Intagliata S; Rescifina A; Salerno L; Di Michele A; Sardella R; Pittalà V
    Bioorg Chem; 2020 Jun; 99():103777. PubMed ID: 32222619
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors.
    Salerno L; Amata E; Romeo G; Marrazzo A; Prezzavento O; Floresta G; Sorrenti V; Barbagallo I; Rescifina A; Pittalà V
    Eur J Med Chem; 2018 Mar; 148():54-62. PubMed ID: 29454190
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, in silico study, synthesis and in vitro evaluation of some N5-(1H-pyrazol-3-yl)-3H-benzo[d]imidazole-2,5-diamine derivatives as potential pancreatic lipase inhibitors for anti-obesity activity.
    Unnisa A; Huwaimel B; Almahmoud S; Abouzied AS; Younes KM; Anupama B; Kola PK; Lakshmi NVKC
    Eur Rev Med Pharmacol Sci; 2022 Oct; 26(19):7245-7255. PubMed ID: 36263535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and evaluation of imidazole-dioxolane compounds as selective heme oxygenase inhibitors: effect of substituents at the 4-position of the dioxolane ring.
    Vlahakis JZ; Hum M; Rahman MN; Jia Z; Nakatsu K; Szarek WA
    Bioorg Med Chem; 2009 Mar; 17(6):2461-75. PubMed ID: 19268600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and ADMET prediction of bis-benzimidazole as anticancer agent.
    Rashid M
    Bioorg Chem; 2020 Mar; 96():103576. PubMed ID: 31986463
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-Activity Relationships of 1,2-Disubstituted Benzimidazoles: Selective Inhibition of Heme Oxygenase-2 Activity.
    Kong X; Vukomanovic D; Nakatsu K; Szarek WA
    ChemMedChem; 2015 Aug; 10(8):1435-41. PubMed ID: 26083133
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 8-(1H-imidazol-1-yl)-7-nitro-4(5H)-imidazo[1,2-alpha]quinoxalinone and related compounds: synthesis and structure-activity relationships for the AMPA-type non-NMDA receptor.
    Ohmori J; Shimizu-Sasamata M; Okada M; Sakamoto S
    J Med Chem; 1997 Jun; 40(13):2053-63. PubMed ID: 9207947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.