BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 34243075)

  • 21. Synthesis of new pyrazoles and pyrozolo [3,4-b] pyridines as anti-inflammatory agents by inhibition of COX-2 enzyme.
    Mohamed LW; Shaaban MA; Zaher AF; Alhamaky SM; Elsahar AM
    Bioorg Chem; 2019 Mar; 83():47-54. PubMed ID: 30342385
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold.
    Bakr RB; Ghoneim AA; Azouz AA
    Bioorg Chem; 2019 Jul; 88():102964. PubMed ID: 31075742
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Novel tetrazole and cyanamide derivatives as inhibitors of cyclooxygenase-2 enzyme: design, synthesis, anti-inflammatory evaluation, ulcerogenic liability and docking study.
    Lamie PF; Philoppes JN; Azouz AA; Safwat NM
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):805-820. PubMed ID: 28587532
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK; Singh VP; Yadav P; Gupta G; Singh A; Goel RK; Shinde P; Mohan CG
    Bioorg Chem; 2014 Oct; 56():8-15. PubMed ID: 24893208
    [TBL] [Abstract][Full Text] [Related]  

  • 25. New imidazolone derivatives comprising a benzoate or sulfonamide moiety as anti-inflammatory and antibacterial inhibitors: Design, synthesis, selective COX-2, DHFR and molecular-modeling study.
    Metwally NH; Mohamed MS
    Bioorg Chem; 2020 Jun; 99():103438. PubMed ID: 31796216
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidines as anti-inflammatory agents.
    Tageldin GN; Fahmy SM; Ashour HM; Khalil MA; Nassra RA; Labouta IM
    Bioorg Chem; 2018 Aug; 78():358-371. PubMed ID: 29627656
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Novel 1-[4-(Aminosulfonyl)phenyl]-1H-1,2,4-triazole derivatives with remarkable selective COX-2 inhibition: design, synthesis, molecular docking, anti-inflammatory and ulcerogenicity studies.
    Abuo-Rahma Gel-D; Abdel-Aziz M; Farag NA; Kaoud TS
    Eur J Med Chem; 2014 Aug; 83():398-408. PubMed ID: 24983538
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and biological evaluations of novel isoxazoles and furoxan derivative as anti-inflammatory agents.
    Abdelall EKA
    Bioorg Chem; 2020 Jan; 94():103441. PubMed ID: 31859011
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis of phenylpiperazine derivatives of 1,4-benzodioxan as selective COX-2 inhibitors and anti-inflammatory agents.
    Sun J; Wang S; Sheng GH; Lian ZM; Liu HY; Zhu HL
    Bioorg Med Chem; 2016 Nov; 24(21):5626-5632. PubMed ID: 27658794
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives.
    Munir A; Khushal A; Saeed K; Sadiq A; Ullah R; Ali G; Ashraf Z; Ullah Mughal E; Saeed Jan M; Rashid U; Hussain I; Mumtaz A
    Bioorg Chem; 2020 Nov; 104():104168. PubMed ID: 32947133
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design, synthesis, anti-inflammatory activity, and molecular docking studies of perimidine derivatives containing triazole.
    Zhang HJ; Wang XZ; Cao Q; Gong GH; Quan ZS
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4409-4414. PubMed ID: 28823493
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis, and biological evaluation of 1,5-diaryl-1,2,4-triazole derivatives as selective cyclooxygenase-2 inhibitors.
    Jiang B; Zeng Y; Li MJ; Xu JY; Zhang YN; Wang QJ; Sun NY; Lu T; Wu XM
    Arch Pharm (Weinheim); 2010 Sep; 343(9):500-8. PubMed ID: 20842641
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA; Labib MB; Abdel-Latif M
    Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
    Abdu-Allah HHM; Abdelmoez AAB; Tarazi H; El-Shorbagi AA; El-Awady R
    Bioorg Chem; 2020 Jan; 94():103378. PubMed ID: 31677858
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis and biological evaluation of new nicotinate derivatives as potential anti-inflammatory agents targeting COX-2 enzyme.
    El-Dash Y; Khalil NA; Ahmed EM; Hassan MSA
    Bioorg Chem; 2021 Feb; 107():104610. PubMed ID: 33454504
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Cyclooxygenase-2 and 15-lipoxygenase inhibition, synthesis, anti-inflammatory activity and ulcer liability of new celecoxib analogues: Determination of region-specific pyrazole ring formation by NOESY.
    Abdelall EKA; Lamie PF; Ali WAM
    Bioorg Med Chem Lett; 2016 Jun; 26(12):2893-2899. PubMed ID: 27158139
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment.
    Marzouk AA; Taher ES; Shaykoon MSA; Lan P; Abd-Allah WH; Aboregela AM; El-Behairy MF
    Bioorg Chem; 2021 Jun; 111():104883. PubMed ID: 33865053
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors.
    Taher ES; Ibrahim TS; Fares M; Al-Mahmoudy AMM; Radwan AF; Orabi KY; El-Sabbagh OI
    Eur J Med Chem; 2019 Jun; 171():372-382. PubMed ID: 30928709
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
    Abdelgawad MA; Labib MB; Ali WAM; Kamel G; Azouz AA; El-Nahass ES
    Bioorg Chem; 2018 Aug; 78():103-114. PubMed ID: 29550530
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
    Gedawy EM; Kassab AE; El Kerdawy AM
    Eur J Med Chem; 2020 Mar; 189():112066. PubMed ID: 31982653
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.