BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 34247441)

  • 1. FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology.
    Du S; Jin F; Maneix L; Gedam M; Xu Y; Catic A; Wang MC; Zheng H
    Aging Cell; 2021 Aug; 20(8):e13432. PubMed ID: 34247441
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice.
    Button EB; Boyce GK; Wilkinson A; Stukas S; Hayat A; Fan J; Wadsworth BJ; Robert J; Martens KM; Wellington CL
    Alzheimers Res Ther; 2019 May; 11(1):44. PubMed ID: 31084613
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-β-Induced Neuronal Death.
    Fernandez AM; Hervas R; Dominguez-Fraile M; Garrido VN; Gomez-Gutierrez P; Vega M; Vitorica J; Perez JJ; Torres Aleman I
    J Alzheimers Dis; 2016 Apr; 52(4):1471-8. PubMed ID: 27079728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease.
    Andersen JV; Skotte NH; Christensen SK; Polli FS; Shabani M; Markussen KH; Haukedal H; Westi EW; Diaz-delCastillo M; Sun RC; Kohlmeier KA; Schousboe A; Gentry MS; Tanila H; Freude KK; Aldana BI; Mann M; Waagepetersen HS
    Cell Death Dis; 2021 Oct; 12(11):954. PubMed ID: 34657143
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Role of Low-Density Lipoprotein Receptor-Related Protein 4 (LRP4) in Astrocytic Aβ Clearance.
    Zhang H; Chen W; Tan Z; Zhang L; Dong Z; Cui W; Zhao K; Wang H; Jing H; Cao R; Kim C; Safar JG; Xiong WC; Mei L
    J Neurosci; 2020 Jul; 40(28):5347-5361. PubMed ID: 32457076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection.
    Iram T; Trudler D; Kain D; Kanner S; Galron R; Vassar R; Barzilai A; Blinder P; Fishelson Z; Frenkel D
    Neurobiol Dis; 2016 Dec; 96():84-94. PubMed ID: 27544484
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease.
    Olsen M; Aguilar X; Sehlin D; Fang XT; Antoni G; Erlandsson A; Syvänen S
    Mol Imaging Biol; 2018 Aug; 20(4):605-614. PubMed ID: 29297157
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual pathways mediate β-amyloid stimulated glutathione release from astrocytes.
    Ye B; Shen H; Zhang J; Zhu YG; Ransom BR; Chen XC; Ye ZC
    Glia; 2015 Dec; 63(12):2208-19. PubMed ID: 26200696
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer's disease.
    Davis N; Mota BC; Stead L; Palmer EOC; Lombardero L; Rodríguez-Puertas R; de Paola V; Barnes SJ; Sastre M
    J Neuroinflammation; 2021 Mar; 18(1):73. PubMed ID: 33731156
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model.
    Chen W; Huang Q; Lazdon EK; Gomes A; Wong M; Stephens E; Royal TG; Frenkel D; Cai W; Kahn CR
    Proc Natl Acad Sci U S A; 2023 May; 120(21):e2220684120. PubMed ID: 37186836
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cdk5-Foxo3 axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models.
    Shi C; Viccaro K; Lee HG; Shah K
    J Cell Sci; 2016 May; 129(9):1815-1830. PubMed ID: 28157684
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
    Mahan TE; Wang C; Bao X; Choudhury A; Ulrich JD; Holtzman DM
    Mol Neurodegener; 2022 Feb; 17(1):13. PubMed ID: 35109920
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia.
    Lee JW; Nam H; Kim LE; Jeon Y; Min H; Ha S; Lee Y; Kim SY; Lee SJ; Kim EK; Yu SW
    Autophagy; 2019 May; 15(5):753-770. PubMed ID: 30523761
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantitative proteomics reveals that PEA15 regulates astroglial Aβ phagocytosis in an Alzheimer's disease mouse model.
    Lv J; Ma S; Zhang X; Zheng L; Ma Y; Zhao X; Lai W; Shen H; Wang Q; Ji J
    J Proteomics; 2014 Oct; 110():45-58. PubMed ID: 25108202
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Peripheral HMGB1 is linked to O
    Ahmed C; Greve HJ; Garza-Lombo C; Malley JA; Johnson JA; Oblak AL; Block ML
    Alzheimers Dement; 2024 May; 20(5):3551-3566. PubMed ID: 38624088
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes.
    Logan S; Pharaoh GA; Marlin MC; Masser DR; Matsuzaki S; Wronowski B; Yeganeh A; Parks EE; Premkumar P; Farley JA; Owen DB; Humphries KM; Kinter M; Freeman WM; Szweda LI; Van Remmen H; Sonntag WE
    Mol Metab; 2018 Mar; 9():141-155. PubMed ID: 29398615
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Scavenger Receptor-A deficiency impairs immune response of microglia and astrocytes potentiating Alzheimer's disease pathophysiology.
    Cornejo F; Vruwink M; Metz C; Muñoz P; Salgado N; Poblete J; Andrés ME; Eugenín J; von Bernhardi R
    Brain Behav Immun; 2018 Mar; 69():336-350. PubMed ID: 29246456
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity.
    Fu W; Shi D; Westaway D; Jhamandas JH
    J Biol Chem; 2015 May; 290(20):12504-13. PubMed ID: 25814669
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
    Sakae N; Liu CC; Shinohara M; Frisch-Daiello J; Ma L; Yamazaki Y; Tachibana M; Younkin L; Kurti A; Carrasquillo MM; Zou F; Sevlever D; Bisceglio G; Gan M; Fol R; Knight P; Wang M; Han X; Fryer JD; Fitzgerald ML; Ohyagi Y; Younkin SG; Bu G; Kanekiyo T
    J Neurosci; 2016 Mar; 36(13):3848-59. PubMed ID: 27030769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. P38K and JNK pathways are induced by amyloid-β in astrocyte: Implication of MAPK pathways in astrogliosis in Alzheimer's disease.
    Saha P; Guha S; Biswas SC
    Mol Cell Neurosci; 2020 Oct; 108():103551. PubMed ID: 32896578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.