BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 34251884)

  • 1. MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival.
    Bacher S; Stekman H; Farah CM; Karger A; Kracht M; Schmitz ML
    Mol Cell Biol; 2021 Sep; 41(10):e0008121. PubMed ID: 34251884
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.
    Benamar M; Guessous F; Du K; Corbett P; Obeid J; Gioeli D; Slingluff CL; Abbas T
    EBioMedicine; 2016 Aug; 10():85-100. PubMed ID: 27333051
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.
    Shibata E; Abbas T; Huang X; Wohlschlegel JA; Dutta A
    Mol Cell Biol; 2011 Aug; 31(15):3136-45. PubMed ID: 21628527
    [TBL] [Abstract][Full Text] [Related]  

  • 4. C/EBPα regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G1/S checkpoint.
    Hall JR; Bereman MS; Nepomuceno AI; Thompson EA; Muddiman DC; Smart RC
    Cell Cycle; 2014; 13(22):3602-10. PubMed ID: 25483090
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.
    Yang Y; He S; Wang Q; Li F; Kwak MJ; Chen S; O'Connell D; Zhang T; Pirooz SD; Jeon YH; Chimge NO; Frenkel B; Choi Y; Aldrovandi GM; Oh BH; Yuan Z; Liang C
    Mol Cell; 2016 May; 62(4):507-19. PubMed ID: 27203177
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis.
    Rizzardi LF; Coleman KE; Varma D; Matson JP; Oh S; Cook JG
    J Biol Chem; 2015 Jan; 290(1):556-67. PubMed ID: 25411249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancer.
    Pan WW; Zhou JJ; Yu C; Xu Y; Guo LJ; Zhang HY; Zhou D; Song FZ; Fan HY
    J Biol Chem; 2013 Oct; 288(41):29680-91. PubMed ID: 23995842
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity.
    Li J; Wang QE; Zhu Q; El-Mahdy MA; Wani G; Praetorius-Ibba M; Wani AA
    Cancer Res; 2006 Sep; 66(17):8590-7. PubMed ID: 16951172
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A.
    Guerrero-Santoro J; Kapetanaki MG; Hsieh CL; Gorbachinsky I; Levine AS; Rapić-Otrin V
    Cancer Res; 2008 Jul; 68(13):5014-22. PubMed ID: 18593899
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DDB2 (damaged-DNA binding protein 2) in nucleotide excision repair and DNA damage response.
    Stoyanova T; Roy N; Kopanja D; Raychaudhuri P; Bagchi S
    Cell Cycle; 2009 Dec; 8(24):4067-71. PubMed ID: 19923893
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factor.
    Chandrasekaran S; Tan TX; Hall JR; Cook JG
    Mol Cell Biol; 2011 Nov; 31(22):4405-16. PubMed ID: 21930785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.
    Abbas T; Sivaprasad U; Terai K; Amador V; Pagano M; Dutta A
    Genes Dev; 2008 Sep; 22(18):2496-506. PubMed ID: 18794347
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.
    Fischer ES; Scrima A; Böhm K; Matsumoto S; Lingaraju GM; Faty M; Yasuda T; Cavadini S; Wakasugi M; Hanaoka F; Iwai S; Gut H; Sugasawa K; Thomä NH
    Cell; 2011 Nov; 147(5):1024-39. PubMed ID: 22118460
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair.
    van Cuijk L; van Belle GJ; Turkyilmaz Y; Poulsen SL; Janssens RC; Theil AF; Sabatella M; Lans H; Mailand N; Houtsmuller AB; Vermeulen W; Marteijn JA
    Nat Commun; 2015 Jul; 6():7499. PubMed ID: 26151477
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule?
    Soria G; Gottifredi V
    DNA Repair (Amst); 2010 Apr; 9(4):358-64. PubMed ID: 20060369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The xeroderma pigmentosum group E gene product DDB2 activates nucleotide excision repair by regulating the level of p21Waf1/Cip1.
    Stoyanova T; Yoon T; Kopanja D; Mokyr MB; Raychaudhuri P
    Mol Cell Biol; 2008 Jan; 28(1):177-87. PubMed ID: 17967871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair.
    Han C; Wani G; Zhao R; Qian J; Sharma N; He J; Zhu Q; Wang QE; Wani AA
    Cell Cycle; 2015; 14(7):1103-15. PubMed ID: 25483071
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) triggers MSH2 and Cdt2 protein-dependent degradation of the cell cycle and mismatch repair (MMR) inhibitor protein p21Waf1/Cip1.
    Jascur T; Fotedar R; Greene S; Hotchkiss E; Boland CR
    J Biol Chem; 2011 Aug; 286(34):29531-9. PubMed ID: 21725088
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase.
    Gao S; Geng C; Song T; Lin X; Liu J; Cai Z; Cang Y
    J Biol Chem; 2017 Mar; 292(9):3683-3691. PubMed ID: 28087699
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CRL4 Ubiquitin Pathway and DNA Damage Response.
    Zhou P; Yan F
    Adv Exp Med Biol; 2020; 1217():225-239. PubMed ID: 31898231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.