These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 34252514)

  • 1. Mycobacterial crypto-AcpM as a tool to investigate the consequence of drug binding on its key FAS II partner enzyme HadAB.
    Singh BK; Biswas R; Basak A; Das AK
    Biochim Biophys Acta Gen Subj; 2021 Oct; 1865(10):129964. PubMed ID: 34252514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The C-terminal end of mycobacterial HadBC regulates AcpM interaction during the FAS-II pathway: a structural perspective.
    Singh BK; Biswas R; Bhattacharyya S; Basak A; Das AK
    FEBS J; 2022 Aug; 289(16):4963-4980. PubMed ID: 35175661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fluorescently labelled thioacetazone for detecting the interaction with
    Singh BK; Singha M; Basak S; Biswas R; Das AK; Basak A
    Org Biomol Chem; 2022 Feb; 20(7):1444-1452. PubMed ID: 35084426
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in
    Singh V; Grzegorzewicz AE; Fienberg S; Müller R; Khonde LP; Sanz O; Alfonso S; Urones B; Drewes G; Bantscheff M; Ghidelli-Disse S; Ioerger TR; Angala B; Liu J; Lee RE; Sacchettini JC; Krieger IV; Jackson M; Chibale K; Ghorpade SR
    ACS Infect Dis; 2022 Nov; 8(11):2315-2326. PubMed ID: 36325756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
    Dong Y; Qiu X; Shaw N; Xu Y; Sun Y; Li X; Li J; Rao Z
    Protein Cell; 2015 Jul; 6(7):504-17. PubMed ID: 26081470
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Covalent modification of the
    Grzegorzewicz AE; Eynard N; Quémard A; North EJ; Margolis A; Lindenberger JJ; Jones V; Korduláková J; Brennan PJ; Lee RE; Ronning DR; McNeil MR; Jackson M
    ACS Infect Dis; 2015 Feb; 1(2):91-97. PubMed ID: 25897434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.
    Sacco E; Covarrubias AS; O'Hare HM; Carroll P; Eynard N; Jones TA; Parish T; Daffé M; Bäckbro K; Quémard A
    Proc Natl Acad Sci U S A; 2007 Sep; 104(37):14628-33. PubMed ID: 17804795
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis.
    Biswas R; Singh BK; Dutta D; Das PK; Maiti MK; Basak A; Das AK
    FEBS Lett; 2019 Mar; 593(6):622-633. PubMed ID: 30847903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of dehydratase component HadAB complex of mycobacterial FAS-II pathway.
    Biswas R; Dutta A; Dutta D; Hazra D; Banerjee DR; Basak A; Das AK
    Biochem Biophys Res Commun; 2015 Mar; 458(2):369-74. PubMed ID: 25656575
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flavonoid inhibitors as novel antimycobacterial agents targeting Rv0636, a putative dehydratase enzyme involved in Mycobacterium tuberculosis fatty acid synthase II.
    Brown AK; Papaemmanouil A; Bhowruth V; Bhatt A; Dover LG; Besra GS
    Microbiology (Reading); 2007 Oct; 153(Pt 10):3314-3322. PubMed ID: 17906131
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB.
    Schaeffer ML; Agnihotri G; Volker C; Kallender H; Brennan PJ; Lonsdale JT
    J Biol Chem; 2001 Dec; 276(50):47029-37. PubMed ID: 11600501
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AcpM, the meromycolate extension acyl carrier protein of Mycobacterium tuberculosis, is activated by the 4'-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.
    Zimhony O; Schwarz A; Raitses-Gurevich M; Peleg Y; Dym O; Albeck S; Burstein Y; Shakked Z
    Biochemistry; 2015 Apr; 54(14):2360-71. PubMed ID: 25785780
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in
    Grzegorzewicz AE; Gee C; Das S; Liu J; Belardinelli JM; Jones V; McNeil MR; Lee RE; Jackson M
    ACS Infect Dis; 2020 Feb; 6(2):195-204. PubMed ID: 31775512
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.
    Kremer L; Nampoothiri KM; Lesjean S; Dover LG; Graham S; Betts J; Brennan PJ; Minnikin DE; Locht C; Besra GS
    J Biol Chem; 2001 Jul; 276(30):27967-74. PubMed ID: 11373295
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression, purification and crystallization of the (3R)-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis.
    Dong Y; Li J; Qiu X; Yan C; Li X
    Protein Expr Purif; 2015 Oct; 114():115-20. PubMed ID: 26118698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis.
    Dym O; Albeck S; Peleg Y; Schwarz A; Shakked Z; Burstein Y; Zimhony O
    J Mol Biol; 2009 Nov; 393(4):937-50. PubMed ID: 19733180
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors.
    Doğan ŞD; Gündüz MG; Doğan H; Krishna VS; Lherbet C; Sriram D
    Eur J Med Chem; 2020 Aug; 199():112402. PubMed ID: 32417538
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression, purification, and characterization of the Mycobacterium tuberculosis acyl carrier protein, AcpM.
    Schaeffer ML; Agnihotri G; Kallender H; Brennan PJ; Lonsdale JT
    Biochim Biophys Acta; 2001 May; 1532(1-2):67-78. PubMed ID: 11420175
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Heterologous expression of mycobacterial proteins in Saccharomyces cerevisiae reveals two physiologically functional 3-hydroxyacyl-thioester dehydratases, HtdX and HtdY, in addition to HadABC and HtdZ.
    Gurvitz A; Hiltunen JK; Kastaniotis AJ
    J Bacteriol; 2009 Apr; 191(8):2683-90. PubMed ID: 19136596
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of isoflavonoids as inhibitors of β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Moraxella catarrhalis: Kinetics, spectroscopic, thermodynamics and in silico studies.
    Kumar V; Sharma A; Pratap S; Kumar P
    Biochim Biophys Acta Gen Subj; 2018 Mar; 1862(3):726-744. PubMed ID: 29092780
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.