BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 34259310)

  • 1. Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965.
    Ahwazi D; Neopane K; Markby GR; Kopietz F; Ovens AJ; Dall M; Hassing AS; Gräsle P; Alshuweishi Y; Treebak JT; Salt IP; Göransson O; Zeqiraj E; Scott JW; Sakamoto K
    Biochem J; 2021 Aug; 478(15):2977-2997. PubMed ID: 34259310
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ULK1/2 and AMPK Inhibitor SBI-0206965 Blocks AICAR and Insulin-Stimulated Glucose Transport.
    Knudsen JR; Madsen AB; Persson KW; Henríquez-Olguín C; Li Z; Jensen TE
    Int J Mol Sci; 2020 Mar; 21(7):. PubMed ID: 32231045
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.
    Dite TA; Langendorf CG; Hoque A; Galic S; Rebello RJ; Ovens AJ; Lindqvist LM; Ngoei KRW; Ling NXY; Furic L; Kemp BE; Scott JW; Oakhill JS
    J Biol Chem; 2018 Jun; 293(23):8874-8885. PubMed ID: 29695504
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of ULK1 Represents a Potential Diagnostic Marker for Clear Cell Renal Carcinoma and the Antitumor Effects of SBI-0206965.
    Lu J; Zhu L; Zheng LP; Cui Q; Zhu HH; Zhao H; Shen ZJ; Dong HY; Chen SS; Wu WZ; Tan JM
    EBioMedicine; 2018 Aug; 34():85-93. PubMed ID: 30078736
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner.
    Kopietz F; Alshuweishi Y; Bijland S; Alghamdi F; Degerman E; Sakamoto K; Salt IP; Göransson O
    Biochem J; 2021 Feb; 478(3):633-646. PubMed ID: 33493298
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.
    Egan DF; Chun MG; Vamos M; Zou H; Rong J; Miller CJ; Lou HJ; Raveendra-Panickar D; Yang CC; Sheffler DJ; Teriete P; Asara JM; Turk BE; Cosford ND; Shaw RJ
    Mol Cell; 2015 Jul; 59(2):285-97. PubMed ID: 26118643
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Irisin alleviates pressure overload-induced cardiac hypertrophy by inducing protective autophagy via mTOR-independent activation of the AMPK-ULK1 pathway.
    Li RL; Wu SS; Wu Y; Wang XX; Chen HY; Xin JJ; Li H; Lan J; Xue KY; Li X; Zhuo CL; Cai YY; He JH; Zhang HY; Tang CS; Wang W; Jiang W
    J Mol Cell Cardiol; 2018 Aug; 121():242-255. PubMed ID: 30053525
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Digitoxin Suppresses Human Cytomegalovirus Replication via Na
    Mukhopadhyay R; Venkatadri R; Katsnelson J; Arav-Boger R
    J Virol; 2018 Mar; 92(6):. PubMed ID: 29321306
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The association of AMPK with ULK1 regulates autophagy.
    Lee JW; Park S; Takahashi Y; Wang HG
    PLoS One; 2010 Nov; 5(11):e15394. PubMed ID: 21072212
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Autophagy-Initiating Protein Kinase ULK1 Phosphorylates Human Cytomegalovirus Tegument Protein pp28 and Regulates Efficient Virus Release.
    König P; Svrlanska A; Read C; Feichtinger S; Stamminger T
    J Virol; 2021 Feb; 95(6):. PubMed ID: 33328309
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AMPK Inhibits ULK1-Dependent Autophagosome Formation and Lysosomal Acidification via Distinct Mechanisms.
    Nwadike C; Williamson LE; Gallagher LE; Guan JL; Chan EYW
    Mol Cell Biol; 2018 May; 38(10):. PubMed ID: 29507183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer.
    Ren H; Bakas NA; Vamos M; Chaikuad A; Limpert AS; Wimer CD; Brun SN; Lambert LJ; Tautz L; Celeridad M; Sheffler DJ; Knapp S; Shaw RJ; Cosford NDP
    J Med Chem; 2020 Dec; 63(23):14609-14625. PubMed ID: 33200929
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.
    Bach M; Larance M; James DE; Ramm G
    Biochem J; 2011 Dec; 440(2):283-91. PubMed ID: 21819378
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Effect of electroacupuncture on hepatocyte autophagy and oxidative stress in SAMP8 mice by regulating AMPK/mTOR/ULK1 signaling pathway].
    Yang YH; Tao CH; Pang F; Yang ZX; Zhu ZW; Guo X; Liao DM; Dai P; Tang CL
    Zhen Ci Yan Jiu; 2022 Jan; 47(1):7-14. PubMed ID: 35128864
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aconitine induces autophagy via activating oxidative DNA damage-mediated AMPK/ULK1 signaling pathway in H9c2 cells.
    Wang W; Jiang J; Huang Y; Peng F; Hu T; Wu J; Pan X; Rao C
    J Ethnopharmacol; 2022 Jan; 282():114631. PubMed ID: 34520828
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Brain Permeable AMP-Activated Protein Kinase Activator R481 Raises Glycaemia by Autonomic Nervous System Activation and Amplifies the Counterregulatory Response to Hypoglycaemia in Rats.
    Cruz AM; Partridge KM; Malekizadeh Y; Vlachaki Walker JM; Weightman Potter PG; Pye KR; Shaw SJ; Ellacott KLJ; Beall C
    Front Endocrinol (Lausanne); 2021; 12():697445. PubMed ID: 34975743
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Excessive ROS production and enhanced autophagy contribute to myocardial injury induced by branched-chain amino acids: Roles for the AMPK-ULK1 signaling pathway and α7nAChR.
    Jiang YJ; Sun SJ; Cao WX; Lan XT; Ni M; Fu H; Li DJ; Wang P; Shen FM
    Biochim Biophys Acta Mol Basis Dis; 2021 Jan; 1867(1):165980. PubMed ID: 32980459
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma.
    Dower CM; Bhat N; Gebru MT; Chen L; Wills CA; Miller BA; Wang HG
    Mol Cancer Ther; 2018 Nov; 17(11):2365-2376. PubMed ID: 30166400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NPM1 mutant maintains ULK1 protein stability via TRAF6-dependent ubiquitination to promote autophagic cell survival in leukemia.
    Tang Y; Tao Y; Wang L; Yang L; Jing Y; Jiang X; Lei L; Yang Z; Wang X; Peng M; Xiao Q; Ren J; Zhang L
    FASEB J; 2021 Feb; 35(2):e21192. PubMed ID: 33201521
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.
    Dite TA; Ling NXY; Scott JW; Hoque A; Galic S; Parker BL; Ngoei KRW; Langendorf CG; O'Brien MT; Kundu M; Viollet B; Steinberg GR; Sakamoto K; Kemp BE; Oakhill JS
    Nat Commun; 2017 Sep; 8(1):571. PubMed ID: 28924239
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.