335 related articles for article (PubMed ID: 34260721)
1. Inhibition of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme of the nicotinamide adenine dinucleotide (NAD) salvage pathway, to target glioma heterogeneity through mitochondrial oxidative stress.
Sharma P; Xu J; Williams K; Easley M; Elder JB; Lonser R; Lang FF; Lapalombella R; Sampath D; Puduvalli VK
Neuro Oncol; 2022 Feb; 24(2):229-244. PubMed ID: 34260721
[TBL] [Abstract][Full Text] [Related]
2. NAMPT: A critical driver and therapeutic target for cancer.
Gasparrini M; Audrito V
Int J Biochem Cell Biol; 2022 Apr; 145():106189. PubMed ID: 35219878
[TBL] [Abstract][Full Text] [Related]
3. Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models.
O'Brien T; Oeh J; Xiao Y; Liang X; Vanderbilt A; Qin A; Yang L; Lee LB; Ly J; Cosino E; LaCap JA; Ogasawara A; Williams S; Nannini M; Liederer BM; Jackson P; Dragovich PS; Sampath D
Neoplasia; 2013 Dec; 15(12):1314-29. PubMed ID: 24403854
[TBL] [Abstract][Full Text] [Related]
4. Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer.
Ju HQ; Zhuang ZN; Li H; Tian T; Lu YX; Fan XQ; Zhou HJ; Mo HY; Sheng H; Chiao PJ; Xu RH
Cancer Lett; 2016 Aug; 379(1):1-11. PubMed ID: 27233476
[TBL] [Abstract][Full Text] [Related]
5. Targeting the NAD
Ye C; Qi L; Li X; Wang J; Yu J; Zhou B; Guo C; Chen J; Zheng S
Cell Commun Signal; 2020 Jan; 18(1):16. PubMed ID: 32005247
[TBL] [Abstract][Full Text] [Related]
6. Both gain and loss of Nampt function promote pressure overload-induced heart failure.
Byun J; Oka SI; Imai N; Huang CY; Ralda G; Zhai P; Ikeda Y; Ikeda S; Sadoshima J
Am J Physiol Heart Circ Physiol; 2019 Oct; 317(4):H711-H725. PubMed ID: 31347918
[TBL] [Abstract][Full Text] [Related]
7. Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer.
Santidrian AF; LeBoeuf SE; Wold ED; Ritland M; Forsyth JS; Felding BH
DNA Repair (Amst); 2014 Nov; 23():79-87. PubMed ID: 25263164
[TBL] [Abstract][Full Text] [Related]
8. Discovery of proqodine A derivatives with antitumor activity targeting NAD(P)H: quinone oxidoreductase 1 and nicotinamide phosphoribosyltransferase.
Song J; Zou G; Zhao Z; Zhu Y; Xue J; Ao L; Sun H; Hao H; Zhang B; Xu X
Chin J Nat Med; 2024 Jan; 22(1):75-88. PubMed ID: 38278561
[TBL] [Abstract][Full Text] [Related]
9. The NAD(+) salvage pathway modulates cancer cell viability via p73.
Sharif T; Ahn DG; Liu RZ; Pringle E; Martell E; Dai C; Nunokawa A; Kwak M; Clements D; Murphy JP; Dean C; Marcato P; McCormick C; Godbout R; Gujar SA; Lee PW
Cell Death Differ; 2016 Apr; 23(4):669-80. PubMed ID: 26586573
[TBL] [Abstract][Full Text] [Related]
10. Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes.
Hsu CP; Oka S; Shao D; Hariharan N; Sadoshima J
Circ Res; 2009 Aug; 105(5):481-91. PubMed ID: 19661458
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells.
Tan B; Dong S; Shepard RL; Kays L; Roth KD; Geeganage S; Kuo MS; Zhao G
J Biol Chem; 2015 Jun; 290(25):15812-15824. PubMed ID: 25944913
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway.
Wang LF; Wang XN; Huang CC; Hu L; Xiao YF; Guan XH; Qian YS; Deng KY; Xin HB
Lipids Health Dis; 2017 Apr; 16(1):82. PubMed ID: 28449683
[TBL] [Abstract][Full Text] [Related]
13. Restoring NAD
Katayoshi T; Nakajo T; Tsuji-Naito K
J Photochem Photobiol B; 2021 Aug; 221():112238. PubMed ID: 34130091
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
Shen Z; Ratia K; Krider I; Ackerman-Berrier M; Penton C; Musku SR; Gordon-Blake JM; Laham MS; Christie N; Ma N; Fu J; Xiong R; Courey JM; Velma GR; Thatcher GRJ
J Med Chem; 2023 Dec; 66(24):16704-16727. PubMed ID: 38096366
[TBL] [Abstract][Full Text] [Related]
15. Effect of Phosphoribosyltransferase Down-regulation on Malignant Glioma Cell Characteristics.
Kamada M; Ikeda K; Manome Y
Anticancer Res; 2020 Sep; 40(9):4895-4905. PubMed ID: 32878777
[TBL] [Abstract][Full Text] [Related]
16. A nicotinamide phosphoribosyltransferase-GAPDH interaction sustains the stress-induced NMN/NAD
Grolla AA; Miggiano R; Di Marino D; Bianchi M; Gori A; Orsomando G; Gaudino F; Galli U; Del Grosso E; Mazzola F; Angeletti C; Guarneri M; Torretta S; Calabrò M; Boumya S; Fan X; Colombo G; Travelli C; Rocchio F; Aronica E; Wohlschlegel JA; Deaglio S; Rizzi M; Genazzani AA; Garavaglia S
J Biol Chem; 2020 Mar; 295(11):3635-3651. PubMed ID: 31988240
[TBL] [Abstract][Full Text] [Related]
17. Different Effects of RNAi-Mediated Downregulation or Chemical Inhibition of NAMPT in an Isogenic IDH Mutant and Wild-Type Glioma Cell Model.
Clausing M; William D; Preussler M; Biedermann J; Grützmann K; Richter S; Buchholz F; Temme A; Schröck E; Klink B
Int J Mol Sci; 2022 May; 23(10):. PubMed ID: 35628596
[TBL] [Abstract][Full Text] [Related]
18. Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.
Zabka TS; Singh J; Dhawan P; Liederer BM; Oeh J; Kauss MA; Xiao Y; Zak M; Lin T; McCray B; La N; Nguyen T; Beyer J; Farman C; Uppal H; Dragovich PS; O'Brien T; Sampath D; Misner DL
Toxicol Sci; 2015 Mar; 144(1):163-72. PubMed ID: 25505128
[TBL] [Abstract][Full Text] [Related]
19. SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.
Sociali G; Grozio A; Caffa I; Schuster S; Becherini P; Damonte P; Sturla L; Fresia C; Passalacqua M; Mazzola F; Raffaelli N; Garten A; Kiess W; Cea M; Nencioni A; Bruzzone S
FASEB J; 2019 Mar; 33(3):3704-3717. PubMed ID: 30514106
[TBL] [Abstract][Full Text] [Related]
20. Nicotinamide Phosphoribosyltransferase-elevated NAD
Zhang Y; Wang Y; Lu S; Zhong R; Liu Z; Zhao Q; Wang C
J Cachexia Sarcopenia Muscle; 2023 Apr; 14(2):1003-1018. PubMed ID: 36864250
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]