BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 34265279)

  • 1. PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1.
    Xu Y; Denning KL; Lu Y
    Biochem Pharmacol; 2021 Oct; 192():114678. PubMed ID: 34265279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alcoholic fatty liver is blunted by rFGF21 administration in mice lacking adipose FGFR1: The role of FGF21 in PPARα-mediated regulation of adipose tissue mass.
    Xu Y; Lu Y
    Biochem Biophys Res Commun; 2022 Sep; 619():84-89. PubMed ID: 35749940
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PPARα agonist WY-14,643 induces the PLA2/COX-2/ACOX1 pathway to enhance peroxisomal lipid metabolism and ameliorate alcoholic fatty liver in mice.
    Xu Y; Denning KL; Lu Y
    Biochem Biophys Res Commun; 2022 Jul; 613():47-52. PubMed ID: 35526488
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis.
    Chen X; Ward SC; Cederbaum AI; Xiong H; Lu Y
    Toxicology; 2017 Mar; 379():12-21. PubMed ID: 28131861
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice.
    Kong L; Ren W; Li W; Zhao S; Mi H; Wang R; Zhang Y; Wu W; Nan Y; Yu J
    Lipids Health Dis; 2011 Dec; 10():246. PubMed ID: 22208561
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis.
    Larter CZ; Yeh MM; Van Rooyen DM; Brooling J; Ghatora K; Farrell GC
    J Gastroenterol Hepatol; 2012 Feb; 27(2):341-50. PubMed ID: 21929649
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase.
    Chen X; Xu Y; Denning KL; Grigore A; Lu Y
    Free Radic Biol Med; 2021 Jun; 169():283-293. PubMed ID: 33892114
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of Myc in hepatocellular proliferation and hepatocarcinogenesis.
    Qu A; Jiang C; Cai Y; Kim JH; Tanaka N; Ward JM; Shah YM; Gonzalez FJ
    J Hepatol; 2014 Feb; 60(2):331-8. PubMed ID: 24096051
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Under peroxisome proliferation acyl-CoA oxidase coordinates with catalase to enhance ethanol metabolism.
    Chen X; Denning KL; Mazur A; Lawrence LM; Wang X; Lu Y
    Free Radic Biol Med; 2023 Nov; 208():221-228. PubMed ID: 37567517
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression.
    Woods CG; Kosyk O; Bradford BU; Ross PK; Burns AM; Cunningham ML; Qu P; Ibrahim JG; Rusyn I
    Toxicol Appl Pharmacol; 2007 Dec; 225(3):267-77. PubMed ID: 17950772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha.
    Pogribny IP; Tryndyak VP; Woods CG; Witt SE; Rusyn I
    Mutat Res; 2007 Dec; 625(1-2):62-71. PubMed ID: 17586532
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha.
    Voss KA; Liu J; Anderson SP; Dunn C; Miller JD; Owen JR; Riley RT; Bacon CW; Corton JC
    Toxicol Sci; 2006 Jan; 89(1):108-19. PubMed ID: 16221962
    [TBL] [Abstract][Full Text] [Related]  

  • 13. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.
    Woods CG; Burns AM; Bradford BU; Ross PK; Kosyk O; Swenberg JA; Cunningham ML; Rusyn I
    Toxicol Sci; 2007 Aug; 98(2):366-74. PubMed ID: 17483499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice.
    Goto T; Hirata M; Aoki Y; Iwase M; Takahashi H; Kim M; Li Y; Jheng HF; Nomura W; Takahashi N; Kim CS; Yu R; Seno S; Matsuda H; Aizawa-Abe M; Ebihara K; Itoh N; Kawada T
    J Biol Chem; 2017 Jun; 292(22):9175-9190. PubMed ID: 28404815
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hepatic Small Ubiquitin-Related Modifier (SUMO)-Specific Protease 2 Controls Systemic Metabolism Through SUMOylation-Dependent Regulation of Liver-Adipose Tissue Crosstalk.
    Liu Y; Dou X; Zhou WY; Ding M; Liu L; Du RQ; Guo L; Qian SW; Tang Y; Yang QQ; Pan DN; Li XY; Lu Y; Cheng JK; Tang QQ
    Hepatology; 2021 Oct; 74(4):1864-1883. PubMed ID: 33934381
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PPARalpha activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes.
    Edvardsson U; Ljungberg A; Lindén D; William-Olsson L; Peilot-Sjögren H; Ahnmark A; Oscarsson J
    J Lipid Res; 2006 Feb; 47(2):329-40. PubMed ID: 16282640
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatic peroxisome proliferator-activated receptor alpha mediates the major metabolic effects of Wy-14643.
    Li G; Brocker CN; Xie C; Yan T; Noguchi A; Krausz KW; Xiang R; Gonzalez FJ
    J Gastroenterol Hepatol; 2018 May; 33(5):1138-1145. PubMed ID: 29141109
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway.
    Xu L; Zhang X; Xin Y; Ma J; Yang C; Zhang X; Hou G; Dong XC; Sun Z; Xiong X; Cao X
    Cell Death Dis; 2021 Jul; 12(7):710. PubMed ID: 34267188
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice.
    Lu Y; Zhuge J; Wang X; Bai J; Cederbaum AI
    Hepatology; 2008 May; 47(5):1483-94. PubMed ID: 18393316
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice.
    Zhao C; Liu Y; Xiao J; Liu L; Chen S; Mohammadi M; McClain CJ; Li X; Feng W
    J Lipid Res; 2015 Aug; 56(8):1481-91. PubMed ID: 26092866
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.