BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 34267186)

  • 21. MEK1-RSK2 contributes to Hedgehog signaling by stabilizing GLI2 transcription factor and inhibiting ubiquitination.
    Liu Z; Li T; Reinhold MI; Naski MC
    Oncogene; 2014 Jan; 33(1):65-73. PubMed ID: 23208494
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction.
    Vaden JH; Bhattacharyya BJ; Chen PC; Watson JA; Marshall AG; Phillips SE; Wilson JA; King GD; Miller RJ; Wilson SM
    Mol Neurodegener; 2015 Jan; 10():3. PubMed ID: 25575639
    [TBL] [Abstract][Full Text] [Related]  

  • 23. GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
    Tolosa EJ; Fernandez-Barrena MG; Iguchi E; McCleary-Wheeler AL; Carr RM; Almada LL; Flores LF; Vera RE; Alfonse GW; Marks DL; Hogenson TL; Vrabel AM; Horn IP; Koenig AN; Safgren SL; Sigafoos AN; Erkan M; Romecin-Duran PA; Sarabia Gonzalez A; Zhou B; Javelaud D; Marsaud V; Graham RP; Mauviel A; Elsawa SF; Fernandez-Zapico ME
    Biochem J; 2020 Sep; 477(17):3131-3145. PubMed ID: 32766732
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Aberrantly activated Gli2-KIF20A axis is crucial for growth of hepatocellular carcinoma and predicts poor prognosis.
    Shi C; Huang D; Lu N; Chen D; Zhang M; Yan Y; Deng L; Lu Q; Lu H; Luo S
    Oncotarget; 2016 May; 7(18):26206-19. PubMed ID: 27036048
    [TBL] [Abstract][Full Text] [Related]  

  • 25. GANT-61 and GDC-0449 induce apoptosis of prostate cancer stem cells through a GLI-dependent mechanism.
    Tong W; Qiu L; Qi M; Liu J; Hu K; Lin W; Huang Y; Fu J
    J Cell Biochem; 2018 Apr; 119(4):3641-3652. PubMed ID: 29231999
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Gli2 Mediated Activation of Hedgehog Signaling Attenuates Acute Pancreatitis via Balancing Inflammatory Cytokines in Mice.
    Liu Z; Lai K; Xie Y; He X; Zhou X
    Cell Physiol Biochem; 2018; 48(1):120-130. PubMed ID: 30001532
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mitogen-activated protein kinases and Hedgehog-GLI signaling in cancer: A crosstalk providing therapeutic opportunities?
    Rovida E; Stecca B
    Semin Cancer Biol; 2015 Dec; 35():154-67. PubMed ID: 26292171
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.
    Bhatia N; Thiyagarajan S; Elcheva I; Saleem M; Dlugosz A; Mukhtar H; Spiegelman VS
    J Biol Chem; 2006 Jul; 281(28):19320-6. PubMed ID: 16651270
    [TBL] [Abstract][Full Text] [Related]  

  • 29.
    Yan J; Hu B; Shi W; Wang X; Shen J; Chen Y; Huang H; Jin L
    Am J Physiol Gastrointest Liver Physiol; 2021 May; 320(5):G720-G728. PubMed ID: 33728992
    [TBL] [Abstract][Full Text] [Related]  

  • 30. DKK1 suppresses WWP2 to enhance bortezomib resistance in multiple myeloma via regulating GLI2 ubiquitination.
    Zhang Q; Gong W; Wu H; Wang J; Jin Q; Lin C; Xu S; Bao W; Wang Y; Wu J; Feng S; Zhao C; Chen B; Liu Z
    Carcinogenesis; 2021 Oct; 42(10):1223-1231. PubMed ID: 34546340
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway.
    Kim EJ; Juhnn YS
    J Biol Chem; 2015 Apr; 290(15):9604-13. PubMed ID: 25713071
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Suppressive GLI2 fragment enhances liver metastasis in colorectal cancer.
    Ogata R; Mori S; Ohmori H; Kishi S; Fujiwara-Tani R; Sasaki T; Nishiguchi Y; Nakashima C; Goto K; Kawahara I; Luo Y; Kuniyasu H
    Oncotarget; 2022; 13():122-135. PubMed ID: 35047127
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Transcription activation of circ-STAT3 induced by Gli2 promotes the progression of hepatoblastoma via acting as a sponge for miR-29a/b/c-3p to upregulate STAT3/Gli2.
    Liu Y; Song J; Liu Y; Zhou Z; Wang X
    J Exp Clin Cancer Res; 2020 Jun; 39(1):101. PubMed ID: 32493490
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Gli affects the stemness and prognosis of epithelial ovarian cancer via homeobox protein NANOG.
    Zhao H; Li N; Pang Y; Zhao J; Wu X
    Mol Med Rep; 2021 Feb; 23(2):. PubMed ID: 33313950
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
    Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
    Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
    [TBL] [Abstract][Full Text] [Related]  

  • 36. FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway.
    Ji W; Yu Y; Li Z; Wang G; Li F; Xia W; Lu S
    Oncotarget; 2016 Mar; 7(12):15118-34. PubMed ID: 26936993
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.
    Yin WC; Satkunendran T; Mo R; Morrissy S; Zhang X; Huang ES; Uusküla-Reimand L; Hou H; Son JE; Liu W; Liu YC; Zhang J; Parker J; Wang X; Farooq H; Selvadurai H; Chen X; Ngan ES; Cheng SY; Dirks PB; Angers S; Wilson MD; Taylor MD; Hui CC
    Dev Cell; 2019 Jan; 48(2):167-183.e5. PubMed ID: 30554998
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Aldehyde dehydrogenase 1A1 stabilizes transcription factor Gli2 and enhances the activity of Hedgehog signaling in hepatocellular cancer.
    Yan Z; Xu L; Zhang J; Lu Q; Luo S; Xu L
    Biochem Biophys Res Commun; 2016 Mar; 471(4):466-73. PubMed ID: 26896768
    [TBL] [Abstract][Full Text] [Related]  

  • 39. c-Jun N-terminal kinase regulates the nucleoplasmic translocation and stability of nucleolar GLTSCR2 protein.
    Lee S; Cho YE; Kim YJ; Park JH
    Biochem Biophys Res Commun; 2016 Mar; 472(1):95-100. PubMed ID: 26903295
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Silencing speckle-type POZ protein by promoter hypermethylation decreases cell apoptosis through upregulating Hedgehog signaling pathway in colorectal cancer.
    Zhi X; Tao J; Zhang L; Tao R; Ma L; Qin J
    Cell Death Dis; 2016 Dec; 7(12):e2569. PubMed ID: 28032859
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.