BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 34267371)

  • 1. p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models.
    Grow EJ; Weaver BD; Smith CM; Guo J; Stein P; Shadle SC; Hendrickson PG; Johnson NE; Butterfield RJ; Menafra R; Kloet SL; van der Maarel SM; Williams CJ; Cairns BR
    Nat Genet; 2021 Aug; 53(8):1207-1220. PubMed ID: 34267371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program.
    Eckersley-Maslin M; Alda-Catalinas C; Blotenburg M; Kreibich E; Krueger C; Reik W
    Genes Dev; 2019 Feb; 33(3-4):194-208. PubMed ID: 30692203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4.
    Eidahl JO; Giesige CR; Domire JS; Wallace LM; Fowler AM; Guckes SM; Garwick-Coppens SE; Labhart P; Harper SQ
    Hum Mol Genet; 2016 Oct; 25(20):4577-4589. PubMed ID: 28173143
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy.
    Bosnakovski D; Gearhart MD; Toso EA; Recht OO; Cucak A; Jain AK; Barton MC; Kyba M
    Dis Model Mech; 2017 Oct; 10(10):1211-1216. PubMed ID: 28754837
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DUX-family transcription factors regulate zygotic genome activation in placental mammals.
    De Iaco A; Planet E; Coluccio A; Verp S; Duc J; Trono D
    Nat Genet; 2017 Jun; 49(6):941-945. PubMed ID: 28459456
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DUX4 expression in cancer induces a metastable early embryonic totipotent program.
    Smith AA; Nip Y; Bennett SR; Hamm DC; Lemmers RJLF; van der Vliet PJ; Setty M; van der Maarel SM; Tapscott SJ
    Cell Rep; 2023 Sep; 42(9):113114. PubMed ID: 37691147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures.
    Haynes P; Kernan K; Zhou SL; Miller DG
    Skelet Muscle; 2017 Jun; 7(1):13. PubMed ID: 28637492
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
    Bosnakovski D; Toso EA; Ener ET; Gearhart MD; Yin L; Lüttmann FF; Magli A; Shi K; Kim J; Aihara H; Kyba M
    iScience; 2023 Oct; 26(10):107823. PubMed ID: 37744032
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The evolution of DUX4 gene regulation and its implication for facioscapulohumeral muscular dystrophy.
    Jagannathan S
    Biochim Biophys Acta Mol Basis Dis; 2022 May; 1868(5):166367. PubMed ID: 35158020
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct interplay between two candidate genes in FSHD muscular dystrophy.
    Ferri G; Huichalaf CH; Caccia R; Gabellini D
    Hum Mol Genet; 2015 Mar; 24(5):1256-66. PubMed ID: 25326393
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DUX4, a candidate gene for facioscapulohumeral muscular dystrophy, causes p53-dependent myopathy in vivo.
    Wallace LM; Garwick SE; Mei W; Belayew A; Coppee F; Ladner KJ; Guttridge D; Yang J; Harper SQ
    Ann Neurol; 2011 Mar; 69(3):540-52. PubMed ID: 21446026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human DUX4 and porcine DUXC activate similar early embryonic programs in pig muscle cells: implications for preclinical models of FSHD.
    Nip Y; Bennett SR; Smith AA; Jones TI; Jones PL; Tapscott SJ
    Hum Mol Genet; 2023 May; 32(11):1864-1874. PubMed ID: 36728804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis.
    Young JM; Whiddon JL; Yao Z; Kasinathan B; Snider L; Geng LN; Balog J; Tawil R; van der Maarel SM; Tapscott SJ
    PLoS Genet; 2013 Nov; 9(11):e1003947. PubMed ID: 24278031
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Canine DUXC: implications for DUX4 retrotransposition and preclinical models of FSHD.
    Wong CJ; Whiddon JL; Langford AT; Belleville AE; Tapscott SJ
    Hum Mol Genet; 2022 May; 31(10):1694-1704. PubMed ID: 34888646
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction.
    Spens AE; Sutliff NA; Bennett SR; Campbell AE; Tapscott SJ
    Elife; 2023 Apr; 12():. PubMed ID: 37092726
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of DUX causes minor defects in zygotic genome activation and is compatible with mouse development.
    Chen Z; Zhang Y
    Nat Genet; 2019 Jun; 51(6):947-951. PubMed ID: 31133747
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conservation and innovation in the DUX4-family gene network.
    Whiddon JL; Langford AT; Wong CJ; Zhong JW; Tapscott SJ
    Nat Genet; 2017 Jun; 49(6):935-940. PubMed ID: 28459454
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DUX4 Role in Normal Physiology and in FSHD Muscular Dystrophy.
    Mocciaro E; Runfola V; Ghezzi P; Pannese M; Gabellini D
    Cells; 2021 Nov; 10(12):. PubMed ID: 34943834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy.
    Shadle SC; Zhong JW; Campbell AE; Conerly ML; Jagannathan S; Wong CJ; Morello TD; van der Maarel SM; Tapscott SJ
    PLoS Genet; 2017 Mar; 13(3):e1006658. PubMed ID: 28273136
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A patient-derived iPSC model revealed oxidative stress increases facioscapulohumeral muscular dystrophy-causative DUX4.
    Sasaki-Honda M; Jonouchi T; Arai M; Hotta A; Mitsuhashi S; Nishino I; Matsuda R; Sakurai H
    Hum Mol Genet; 2018 Dec; 27(23):4024-4035. PubMed ID: 30107443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.