159 related articles for article (PubMed ID: 34270935)
1. Bifunctional modalities for repurposing protein function.
Modell AE; Lai S; Nguyen TM; Choudhary A
Cell Chem Biol; 2021 Jul; 28(7):1081-1089. PubMed ID: 34270935
[TBL] [Abstract][Full Text] [Related]
2. Proximity-inducing modalities: the past, present, and future.
Singh S; Tian W; Severance ZC; Chaudhary SK; Anokhina V; Mondal B; Pergu R; Singh P; Dhawa U; Singha S; Choudhary A
Chem Soc Rev; 2023 Aug; 52(16):5485-5515. PubMed ID: 37477631
[TBL] [Abstract][Full Text] [Related]
3. Bifunctional chemical probes inducing protein-protein interactions.
Maniaci C; Ciulli A
Curr Opin Chem Biol; 2019 Oct; 52():145-156. PubMed ID: 31419624
[TBL] [Abstract][Full Text] [Related]
4. Molecular glues and bifunctional compounds: Therapeutic modalities based on induced proximity.
Schreiber SL
Cell Chem Biol; 2024 Jun; 31(6):1050-1063. PubMed ID: 38861986
[TBL] [Abstract][Full Text] [Related]
5. Design and Applications of Bifunctional Small Molecules: Why Two Heads Are Better Than One.
Corson TW; Aberle N; Crews CM
ACS Chem Biol; 2008 Nov; 3(11):677-692. PubMed ID: 19112665
[TBL] [Abstract][Full Text] [Related]
6. Phosphorylation-Inducing Chimeric Small Molecules.
Siriwardena SU; Munkanatta Godage DNP; Shoba VM; Lai S; Shi M; Wu P; Chaudhary SK; Schreiber SL; Choudhary A
J Am Chem Soc; 2020 Aug; 142(33):14052-14057. PubMed ID: 32787262
[TBL] [Abstract][Full Text] [Related]
7. PROTACs, molecular glues and bifunctionals from bench to bedside: Unlocking the clinical potential of catalytic drugs.
Maneiro M; De Vita E; Conole D; Kounde CS; Zhang Q; Tate EW
Prog Med Chem; 2021; 60():67-190. PubMed ID: 34147206
[TBL] [Abstract][Full Text] [Related]
8. Targeted protein degradation by PROTACs.
Neklesa TK; Winkler JD; Crews CM
Pharmacol Ther; 2017 Jun; 174():138-144. PubMed ID: 28223226
[TBL] [Abstract][Full Text] [Related]
9. Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs.
Alabi SB; Crews CM
J Biol Chem; 2021; 296():100647. PubMed ID: 33839157
[TBL] [Abstract][Full Text] [Related]
10. PROTACs: An Emerging Targeting Technique for Protein Degradation in Drug Discovery.
Gu S; Cui D; Chen X; Xiong X; Zhao Y
Bioessays; 2018 Apr; 40(4):e1700247. PubMed ID: 29473971
[TBL] [Abstract][Full Text] [Related]
11. PROTACs- a game-changing technology.
Konstantinidou M; Li J; Zhang B; Wang Z; Shaabani S; Ter Brake F; Essa K; Dömling A
Expert Opin Drug Discov; 2019 Dec; 14(12):1255-1268. PubMed ID: 31538491
[No Abstract] [Full Text] [Related]
12. Small molecule PROTACs in targeted therapy: An emerging strategy to induce protein degradation.
Xi M; Chen Y; Yang H; Xu H; Du K; Wu C; Xu Y; Deng L; Luo X; Yu L; Wu Y; Gao X; Cai T; Chen B; Shen R; Sun H
Eur J Med Chem; 2019 Jul; 174():159-180. PubMed ID: 31035238
[TBL] [Abstract][Full Text] [Related]
13. Kinase-targeting small-molecule inhibitors and emerging bifunctional molecules.
Goebel GL; Qiu X; Wu P
Trends Pharmacol Sci; 2022 Oct; 43(10):866-881. PubMed ID: 35589447
[TBL] [Abstract][Full Text] [Related]
14. Chemical-Mediated Targeted Protein Degradation in Neurodegenerative Diseases.
Hyun S; Shin D
Life (Basel); 2021 Jun; 11(7):. PubMed ID: 34202541
[TBL] [Abstract][Full Text] [Related]
15. PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics.
Khan S; He Y; Zhang X; Yuan Y; Pu S; Kong Q; Zheng G; Zhou D
Oncogene; 2020 Jun; 39(26):4909-4924. PubMed ID: 32475992
[TBL] [Abstract][Full Text] [Related]
16. Protein degradation: a validated therapeutic strategy with exciting prospects.
Lebraud H; Heightman TD
Essays Biochem; 2017 Nov; 61(5):517-527. PubMed ID: 28970340
[TBL] [Abstract][Full Text] [Related]
17. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins.
Buckley DL; Raina K; Darricarrere N; Hines J; Gustafson JL; Smith IE; Miah AH; Harling JD; Crews CM
ACS Chem Biol; 2015 Aug; 10(8):1831-7. PubMed ID: 26070106
[TBL] [Abstract][Full Text] [Related]
18. Targeted Protein Degradation by Small Molecules.
Bondeson DP; Crews CM
Annu Rev Pharmacol Toxicol; 2017 Jan; 57():107-123. PubMed ID: 27732798
[TBL] [Abstract][Full Text] [Related]
19. Two in one: the emerging concept of bifunctional antibodies.
Rhee K; Zhou X
Curr Opin Biotechnol; 2024 Feb; 85():103050. PubMed ID: 38142645
[TBL] [Abstract][Full Text] [Related]
20. Induced degradation of protein kinases by bifunctional small molecules: a next-generation strategy.
Groppe JC
Expert Opin Drug Discov; 2019 Dec; 14(12):1237-1253. PubMed ID: 31513432
[No Abstract] [Full Text] [Related]
[Next] [New Search]