BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 34270935)

  • 21. Monitoring and deciphering protein degradation pathways inside cells.
    Daniels DL; Riching KM; Urh M
    Drug Discov Today Technol; 2019 Apr; 31():61-68. PubMed ID: 31200861
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Unifying principles of bifunctional, proximity-inducing small molecules.
    Gerry CJ; Schreiber SL
    Nat Chem Biol; 2020 Apr; 16(4):369-378. PubMed ID: 32198490
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs).
    Tomaselli D; Mautone N; Mai A; Rotili D
    Eur J Med Chem; 2020 Dec; 207():112750. PubMed ID: 32871345
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design and pharmaceutical applications of proteolysis-targeting chimeric molecules.
    Liang Y; Nandakumar KS; Cheng K
    Biochem Pharmacol; 2020 Dec; 182():114211. PubMed ID: 32866456
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Targeted Protein Degradation by Chimeric Small Molecules, PROTACs and SNIPERs.
    Naito M; Ohoka N; Shibata N; Tsukumo Y
    Front Chem; 2019; 7():849. PubMed ID: 31921772
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Understanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical Applications.
    Goracci L; Desantis J; Valeri A; Castellani B; Eleuteri M; Cruciani G
    J Med Chem; 2020 Oct; 63(20):11615-11638. PubMed ID: 33026811
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras.
    Lebraud H; Wright DJ; Johnson CN; Heightman TD
    ACS Cent Sci; 2016 Dec; 2(12):927-934. PubMed ID: 28058282
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation.
    Donoghue C; Cubillos-Rojas M; Gutierrez-Prat N; Sanchez-Zarzalejo C; Verdaguer X; Riera A; Nebreda AR
    Eur J Med Chem; 2020 Sep; 201():112451. PubMed ID: 32634680
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery.
    Dong G; Ding Y; He S; Sheng C
    J Med Chem; 2021 Aug; 64(15):10606-10620. PubMed ID: 34319094
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Haven't got a glue: Protein surface variation for the design of molecular glue degraders.
    Kozicka Z; Thomä NH
    Cell Chem Biol; 2021 Jul; 28(7):1032-1047. PubMed ID: 33930325
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Proteolysis-targeting chimeras for targeting protein for degradation.
    Qi J; Zhang G
    Future Med Chem; 2019 Apr; 11(7):723-741. PubMed ID: 30706727
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation.
    Kannt A; Đikić I
    Cell Chem Biol; 2021 Jul; 28(7):1014-1031. PubMed ID: 33945791
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Acute Pharmacologic Degradation of a Stable Antigen Enhances Its Direct Presentation on MHC Class I Molecules.
    Moser SC; Voerman JSA; Buckley DL; Winter GE; Schliehe C
    Front Immunol; 2017; 8():1920. PubMed ID: 29358938
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Optochemical Control of Protein Degradation.
    Wu P; Manna D
    Chembiochem; 2020 Aug; 21(16):2250-2252. PubMed ID: 32227452
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Controlling PROTACs with Light.
    Verma S; Manna D
    ChemMedChem; 2020 Jul; 15(14):1258-1261. PubMed ID: 32558301
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Chemically induced proximity in biology and medicine.
    Stanton BZ; Chory EJ; Crabtree GR
    Science; 2018 Mar; 359(6380):. PubMed ID: 29590011
    [TBL] [Abstract][Full Text] [Related]  

  • 37. RNA-PROTACs: Degraders of RNA-Binding Proteins.
    Ghidini A; Cléry A; Halloy F; Allain FHT; Hall J
    Angew Chem Int Ed Engl; 2021 Feb; 60(6):3163-3169. PubMed ID: 33108679
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Preclinical Studies of PROTACs in Hematological Malignancies.
    Fuchs O; Bokorova R
    Cardiovasc Hematol Disord Drug Targets; 2021; 21(1):7-22. PubMed ID: 33687890
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.
    Okuhira K; Shoda T; Omura R; Ohoka N; Hattori T; Shibata N; Demizu Y; Sugihara R; Ichino A; Kawahara H; Itoh Y; Ishikawa M; Hashimoto Y; Kurihara M; Itoh S; Saito H; Naito M
    Mol Pharmacol; 2017 Mar; 91(3):159-166. PubMed ID: 27965304
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Molecular glues modulate protein functions by inducing protein aggregation: A promising therapeutic strategy of small molecules for disease treatment.
    Wu H; Yao H; He C; Jia Y; Zhu Z; Xu S; Li D; Xu J
    Acta Pharm Sin B; 2022 Sep; 12(9):3548-3566. PubMed ID: 36176907
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.