133 related articles for article (PubMed ID: 34273619)
1. Modeling a human CLP1 mutation in mouse identifies an accumulation of tyrosine pre-tRNA fragments causing pontocerebellar hypoplasia type 10.
Morisaki I; Shiraishi H; Fujinami H; Shimizu N; Hikida T; Arai Y; Kobayashi T; Hanada R; Penninger JM; Fujiki M; Hanada T
Biochem Biophys Res Commun; 2021 Sep; 570():60-66. PubMed ID: 34273619
[TBL] [Abstract][Full Text] [Related]
2. The
Monaghan CE; Adamson SI; Kapur M; Chuang JH; Ackerman SL
Proc Natl Acad Sci U S A; 2021 Sep; 118(39):. PubMed ID: 34548404
[TBL] [Abstract][Full Text] [Related]
3. 2 new cases of pontocerebellar hypoplasia type 10 identified by whole exome sequencing in a Turkish family.
Wafik M; Taylor J; Lester T; Gibbons RJ; Shears DJ
Eur J Med Genet; 2018 May; 61(5):273-279. PubMed ID: 29307788
[TBL] [Abstract][Full Text] [Related]
4. Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
Sekulovski S; Devant P; Panizza S; Gogakos T; Pitiriciu A; Heitmeier K; Ramsay EP; Barth M; Schmidt C; Tuschl T; Baas F; Weitzer S; Martinez J; Trowitzsch S
Nat Commun; 2021 Sep; 12(1):5610. PubMed ID: 34584079
[TBL] [Abstract][Full Text] [Related]
5. Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.
Karaca E; Weitzer S; Pehlivan D; Shiraishi H; Gogakos T; Hanada T; Jhangiani SN; Wiszniewski W; Withers M; Campbell IM; Erdin S; Isikay S; Franco LM; Gonzaga-Jauregui C; Gambin T; Gelowani V; Hunter JV; Yesil G; Koparir E; Yilmaz S; Brown M; Briskin D; Hafner M; Morozov P; Farazi TA; Bernreuther C; Glatzel M; Trattnig S; Friske J; Kronnerwetter C; Bainbridge MN; Gezdirici A; Seven M; Muzny DM; Boerwinkle E; Ozen M; ; Clausen T; Tuschl T; Yuksel A; Hess A; Gibbs RA; Martinez J; Penninger JM; Lupski JR
Cell; 2014 Apr; 157(3):636-50. PubMed ID: 24766809
[TBL] [Abstract][Full Text] [Related]
6. CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.
Schaffer AE; Eggens VR; Caglayan AO; Reuter MS; Scott E; Coufal NG; Silhavy JL; Xue Y; Kayserili H; Yasuno K; Rosti RO; Abdellateef M; Caglar C; Kasher PR; Cazemier JL; Weterman MA; Cantagrel V; Cai N; Zweier C; Altunoglu U; Satkin NB; Aktar F; Tuysuz B; Yalcinkaya C; Caksen H; Bilguvar K; Fu XD; Trotta CR; Gabriel S; Reis A; Gunel M; Baas F; Gleeson JG
Cell; 2014 Apr; 157(3):651-63. PubMed ID: 24766810
[TBL] [Abstract][Full Text] [Related]
7. CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders.
Weitzer S; Hanada T; Penninger JM; Martinez J
Wiley Interdiscip Rev RNA; 2015; 6(1):47-63. PubMed ID: 25142875
[TBL] [Abstract][Full Text] [Related]
8. What connects splicing of transfer RNA precursor molecules with pontocerebellar hypoplasia?
Sekulovski S; Trowitzsch S
Bioessays; 2023 Feb; 45(2):e2200130. PubMed ID: 36517085
[TBL] [Abstract][Full Text] [Related]
9. Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage.
Hayne CK; Schmidt CA; Haque MI; Matera AG; Stanley RE
Nucleic Acids Res; 2020 Aug; 48(14):7609-7622. PubMed ID: 32476018
[TBL] [Abstract][Full Text] [Related]
10. CLP1 links tRNA metabolism to progressive motor-neuron loss.
Hanada T; Weitzer S; Mair B; Bernreuther C; Wainger BJ; Ichida J; Hanada R; Orthofer M; Cronin SJ; Komnenovic V; Minis A; Sato F; Mimata H; Yoshimura A; Tamir I; Rainer J; Kofler R; Yaron A; Eggan KC; Woolf CJ; Glatzel M; Herbst R; Martinez J; Penninger JM
Nature; 2013 Mar; 495(7442):474-80. PubMed ID: 23474986
[TBL] [Abstract][Full Text] [Related]
11. Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia.
Schmidt CA; Min LY; McVay MH; Giusto JD; Brown JC; Salzler HR; Matera AG
Biol Open; 2022 Mar; 11(3):. PubMed ID: 35132432
[TBL] [Abstract][Full Text] [Related]
12. Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2.
Inoue M; Hada K; Shiraishi H; Yatsuka H; Fujinami H; Morisaki I; Nishida Y; Matsubara E; Ishitani T; Hanada R; Matsumoto M; Penninger JM; Ihara K; Hanada T
Biochem Biophys Res Commun; 2020 May; 525(3):726-732. PubMed ID: 32143824
[TBL] [Abstract][Full Text] [Related]
13. Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components.
Mair B; Popow J; Mechtler K; Weitzer S; Martinez J
Biochem Soc Trans; 2013 Aug; 41(4):831-7. PubMed ID: 23863140
[TBL] [Abstract][Full Text] [Related]
14. Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN.
Sekulovski S; Sušac L; Stelzl LS; Tampé R; Trowitzsch S
Nat Struct Mol Biol; 2023 Jun; 30(6):834-840. PubMed ID: 37231152
[TBL] [Abstract][Full Text] [Related]
15. Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo.
Ramirez A; Shuman S; Schwer B
RNA; 2008 Sep; 14(9):1737-45. PubMed ID: 18648070
[TBL] [Abstract][Full Text] [Related]
16. Recent insights into the structure, function, and regulation of the eukaryotic transfer RNA splicing endonuclease complex.
Hayne CK; Lewis TA; Stanley RE
Wiley Interdiscip Rev RNA; 2022 Sep; 13(5):e1717. PubMed ID: 35156311
[TBL] [Abstract][Full Text] [Related]
17. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.
Chai G; Webb A; Li C; Antaki D; Lee S; Breuss MW; Lang N; Stanley V; Anzenberg P; Yang X; Marshall T; Gaffney P; Wierenga KJ; Chung BH; Tsang MH; Pais LS; Lovgren AK; VanNoy GE; Rehm HL; Mirzaa G; Leon E; Diaz J; Neumann A; Kalverda AP; Manfield IW; Parry DA; Logan CV; Johnson CA; Bonthron DT; Valleley EMA; Issa MY; Abdel-Ghafar SF; Abdel-Hamid MS; Jennings P; Zaki MS; Sheridan E; Gleeson JG
Neuron; 2021 Jan; 109(2):241-256.e9. PubMed ID: 33220177
[TBL] [Abstract][Full Text] [Related]
18. Arabidopsis CLP1-SIMILAR PROTEIN3, an ortholog of human polyadenylation factor CLP1, functions in gametophyte, embryo, and postembryonic development.
Xing D; Zhao H; Li QQ
Plant Physiol; 2008 Dec; 148(4):2059-69. PubMed ID: 18971429
[TBL] [Abstract][Full Text] [Related]
19. Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex.
Hayne CK; Butay KJU; Stewart ZD; Krahn JM; Perera L; Williams JG; Petrovitch RM; Deterding LJ; Matera AG; Borgnia MJ; Stanley RE
Nat Struct Mol Biol; 2023 Jun; 30(6):824-833. PubMed ID: 37231153
[TBL] [Abstract][Full Text] [Related]
20. Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
LaForce GR; Farr JS; Liu J; Akesson C; Gumus E; Pinkard O; Miranda HC; Johnson K; Sweet TJ; Ji P; Lin A; Coller J; Philippidou P; Wagner EJ; Schaffer AE
Neuron; 2022 Apr; 110(8):1340-1357.e7. PubMed ID: 35139363
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]