BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 34275172)

  • 1. PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
    Dasgupta A; Chen KH; Lima PDA; Mewburn J; Wu D; Al-Qazazi R; Jones O; Tian L; Potus F; Bonnet S; Archer SL
    FASEB J; 2021 Aug; 35(8):e21771. PubMed ID: 34275172
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PGC1α-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.
    Ryan JJ; Marsboom G; Fang YH; Toth PT; Morrow E; Luo N; Piao L; Hong Z; Ericson K; Zhang HJ; Han M; Haney CR; Chen CT; Sharp WW; Archer SL
    Am J Respir Crit Care Med; 2013 Apr; 187(8):865-78. PubMed ID: 23449689
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy.
    Xian H; Liou YC
    Autophagy; 2019 Dec; 15(12):2107-2125. PubMed ID: 30894073
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
    Chen KH; Dasgupta A; Lin J; Potus F; Bonnet S; Iremonger J; Fu J; Mewburn J; Wu D; Dunham-Snary K; Theilmann AL; Jing ZC; Hindmarch C; Ormiston ML; Lawrie A; Archer SL
    Circulation; 2018 Jul; 138(3):287-304. PubMed ID: 29431643
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes NRF2-Independent Mitochondrial Fusion through CXCR4/PSMB5-Mediated Drp1 Degradation in Endothelial Cells.
    Zhang S; Feng F; Dai J; Li J; Bu X; Xie X
    Oxid Med Cell Longev; 2021; 2021():9993240. PubMed ID: 34394840
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Upregulated miR-17 Regulates Hypoxia-Mediated Human Pulmonary Artery Smooth Muscle Cell Proliferation and Apoptosis by Targeting Mitofusin 2.
    Lu Z; Li S; Zhao S; Fa X
    Med Sci Monit; 2016 Sep; 22():3301-8. PubMed ID: 27640178
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease.
    Li C; Liu Q; Chang Q; Xie M; Weng J; Wang X; Li M; Chen J; Huang Y; Yang X; Wang K; Zhang N; Chung KF; Adcock IM; Zhang H; Li F
    Respir Res; 2023 Dec; 24(1):319. PubMed ID: 38110986
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease.
    Dagda RK; Gusdon AM; Pien I; Strack S; Green S; Li C; Van Houten B; Cherra SJ; Chu CT
    Cell Death Differ; 2011 Dec; 18(12):1914-23. PubMed ID: 21637291
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.
    Li J; Dang X; Franco A; Dorn GW
    Front Cell Dev Biol; 2022; 10():868465. PubMed ID: 35646911
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial dynamics in pulmonary arterial hypertension.
    Ryan J; Dasgupta A; Huston J; Chen KH; Archer SL
    J Mol Med (Berl); 2015 Mar; 93(3):229-42. PubMed ID: 25672499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutation of the protein kinase A phosphorylation site influences the anti-proliferative activity of mitofusin 2.
    Zhou W; Chen KH; Cao W; Zeng J; Liao H; Zhao L; Guo X
    Atherosclerosis; 2010 Jul; 211(1):216-23. PubMed ID: 20303493
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma.
    Lou Y; Li R; Liu J; Zhang Y; Zhang X; Jin B; Liu Y; Wang Z; Zhong H; Wen S; Han B
    Med Oncol; 2015 Apr; 32(4):132. PubMed ID: 25796500
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis.
    Bhatia D; Chung KP; Nakahira K; Patino E; Rice MC; Torres LK; Muthukumar T; Choi AM; Akchurin OM; Choi ME
    JCI Insight; 2019 Dec; 4(23):. PubMed ID: 31639106
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4.
    Zhang J; Pan L; Zhang Q; Zhao Y; Wang W; Lin N; Zhang S; Wu Q
    FEBS Open Bio; 2023 Jun; 13(6):1107-1124. PubMed ID: 36877954
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.
    Rocha AG; Franco A; Krezel AM; Rumsey JM; Alberti JM; Knight WC; Biris N; Zacharioudakis E; Janetka JW; Baloh RH; Kitsis RN; Mochly-Rosen D; Townsend RR; Gavathiotis E; Dorn GW
    Science; 2018 Apr; 360(6386):336-341. PubMed ID: 29674596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes.
    O'Flanagan CH; Morais VA; Wurst W; De Strooper B; O'Neill C
    Oncogene; 2015 Mar; 34(11):1363-74. PubMed ID: 24681957
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.
    Leboucher GP; Tsai YC; Yang M; Shaw KC; Zhou M; Veenstra TD; Glickman MH; Weissman AM
    Mol Cell; 2012 Aug; 47(4):547-57. PubMed ID: 22748923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
    Chen Y; Dorn GW
    Science; 2013 Apr; 340(6131):471-5. PubMed ID: 23620051
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Skeletal muscle dysfunction in idiopathic pulmonary arterial hypertension.
    Batt J; Ahmed SS; Correa J; Bain A; Granton J
    Am J Respir Cell Mol Biol; 2014 Jan; 50(1):74-86. PubMed ID: 23972212
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitofusin-2 Triggers Cervical Carcinoma Cell Hela Apoptosis via Mitochondrial Pathway in Mouse Model.
    Wang W; Liu X; Guo X; Quan H
    Cell Physiol Biochem; 2018; 46(1):69-81. PubMed ID: 29587277
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.